Smaller pelvic volume is associated with postoperative infection after pelvic salvage surgery for recurrent malignancy.

Abstract:

BACKGROUND:Patients with recurrent pelvic malignancy have few treatment options, and surgery is fraught with complications. We sought to characterize the relationship between radiographic pelvic volume and postoperative complications after pelvic salvage surgery. METHODS:A retrospective chart review of all patients undergoing pelvic exenteration or abdominoperineal resection for recurrent malignancy between 1998 and 2013 was performed. Preoperative computed tomography was used to determine pelvic volume. RESULTS:Forty-two patients underwent surgery for recurrent rectal (26, 62%), prostate (8, 19%), or anal squamous cell cancer (8, 19%). Thirty-eight patients (90%) suffered complications and there was one (2%) perioperative death. Decreasing pelvic volume was associated with deep or organ space infections (P = .01), sepsis (P = .03), and fistula (P = .05) on univariate analysis. Infections remained significant on multivariate analysis (odds ratio, 1.01; P = .02). CONCLUSIONS:Pelvic salvage surgery for recurrent malignancy is associated with a high complication rate yet low mortality. Decreasing pelvic volume is associated with increasing risk of deep or organ space infections.

journal_name

Am J Surg

authors

Jones EL,Jones TS,Paniccia A,Merkow JS,Wells DM,Pearlman NW,McCarter MD

doi

10.1016/j.amjsurg.2014.08.015

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

1016-22; discussion 1021-2

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(14)00451-6

journal_volume

208

pub_type

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