Timing of treatment for nonneutropenic patients colonized with Candida.

Abstract:

:There has been a continuing evolution of the clinical spectrum of Candida infection in nonneutropenic patients. With better understanding of the predisposing factors for fungemia in critically ill patients, interest now centers on indications for early therapy, prior to the progression of colonization to fungemia. Recent prospective trials have identified persistence of Candida species in repetitive cultures of various sites as an essential if not necessary precursor for fungemia. Treatment for patients requiring prolonged intensive-care-unit residence and demonstrating colonization with Candida is suggested, based on the frequency with which such patients progress to fungemia. The efficacy of such treatment is undocumented, and clinical trials of various regimens of polyene or azole antifungals is needed.

journal_name

Am J Surg

authors

Solomkin JS

doi

10.1016/s0002-9610(96)00350-9

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

44S-48S

issue

6A

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(96)00350-9

journal_volume

172

pub_type

杂志文章,评审
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    更新日期:1988-01-01 00:00:00

  • Metastatic phalangeal osteolysis as an initial presentation of carcinoma colon.

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  • In situ saphenous vein bypass grafting. Experience in 34 extremities over a 2 year period.

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    更新日期:1998-11-01 00:00:00