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Clofibrate-induced muscular syndrome. Report of a case with clinical, electromyographic and pathologic observations.

Abstract：

:In this report the clinical features of a case of clofibrate-induced muscular syndrome, as well as the electromyographic, histochemical, light- and electron-microscopic findings are described. The clinical features are similar to those of previously reported cases. Electromyography was consistent with a myopathy. Histochemical profile was normal. The myopathology included breakdown of contractile material, deranged mitochondria, dilated sarcoplasmic reticulum profiles, accumulation of membrane bound dense bodies, discontinuities in sarcolemma and thickening of capillary basement membrane. Macrophages invaded severely affected fibers.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Abourizk N,Khalil BA,Bahuth N,Afifi AK

doi

10.1016/0022-510x(79)90149-7

subject

Has Abstract

pub_date

1979-06-01 00:00:00

pages

1-9

issue

1

eissn

0022-510X

issn

1878-5883

pii

0022-510X(79)90149-7

journal_volume

42

pub_type

杂志文章

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