当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > A sensitive method for the detection and quantification of conduction deficits in nerve.

A sensitive method for the detection and quantification of conduction deficits in nerve.

Abstract：

:A method is described which characterises the conduction deficit of a nerve in terms of the distribution of the refractory periods of transmission (RPTs) of its constituent fibres. The RPT is a particularly sensitive index of conduction deficit and measures the ability of a nerve fibre to conduct pairs of closely spaced impulses. The distribution of RPT in the nerve is represented as a graph, the RPT spectrum. Although the RPT spectrum is derived from recordings of the monophasic compound action potential, it is independent of changes in the conduction velocity of the constituent nerve fibres. The method is a particular value in the investigation lf lesions which are short or in which only a small proportion of the fibres present are affected. An investigation is described which examines the similarity between the RPT spectrum, derived from recordings of the compound action potential, and the frequency distribution histogram of RPT derived from a study of individual fibres from the same nerve. A recent study (Smith and Hall 1980) has shown that when the conduction deficit resulting from a lesion is described in terms of the RPT spectrum, a close correlation can be drawn between the physiological properties of the nerve, its histological appearance at the lesion, and the severity of the resulting behavioural deficit.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Smith KJ

doi

10.1016/0022-510x(80)90200-2

subject

Has Abstract

pub_date

1980-11-01 00:00:00

pages

191-9

issue

2

eissn

0022-510X

issn

1878-5883

pii

0022-510X(80)90200-2

journal_volume

48

pub_type

杂志文章

相关文献

JOURNAL OF THE NEUROLOGICAL SCIENCES文献大全
  • Accelerometer cut-points derived during over-ground walking in persons with mild, moderate, and severe multiple sclerosis.

    abstract：BACKGROUND:There has been increased interest in objectively quantifying time spent in moderate-to-vigorous physical activity (MVPA) using accelerometry as an outcome among persons with multiple sclerosis (MS). This requires development of a cut-point for interpreting the rate of accelerometer output based on its associ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.02.024

    authors： Sandroff BM,Riskin BJ,Agiovlasitis S,Motl RW

    更新日期：2014-05-15 00:00:00

  • Anoxia in vitro does not induce neuronal swelling or death.

    abstract：:To improve the understanding of neuronal cell swelling in cerebral ischemia, cell volume regulation, viability, intracellular electrolytes, and lactate production of Neuro-2A neuroblastoma cells were studied using an in vitro model. The volume regulatory capacity of Neuro-2A cells was assessed after incubation in hypo...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：

    authors： Mackert BM,Staub F,Peters J,Baethmann A,Kempski O

    更新日期：1996-07-01 00:00:00

  • Recovery of thalamic microstructural damage after Shiga toxin 2-associated hemolytic-uremic syndrome.

    abstract：INTRODUCTION:The underlying pathophysiology of neurological complications in patients with hemolytic-uremic syndrome (HUS) remains unclear. It was recently attributed to a direct cytotoxic effect of Shiga toxin 2 (Stx2) in the thalamus. Conventional MRI of patients with Stx2-caused HUS revealed - despite severe neurolo...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.06.045

    authors： Krämer J,Deppe M,Göbel K,Tabelow K,Wiendl H,Meuth SG

    更新日期：2015-09-15 00:00:00

  • Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.

    abstract：:The mitochondria have several important functions in the cell. A mitochondrial dysfunction causes an abatement in ATP production, oxidative damage and the induction of apoptosis, all of which are involved in the pathogenesis of numerous disorders. This review focuses on mitochondrial dysfunctions and discusses their c...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2007.01.033

    authors： Sas K,Robotka H,Toldi J,Vécsei L

    更新日期：2007-06-15 00:00:00

  • Paradoxical brain embolism in an acute stroke.

    abstract：:Paradoxical embolism to the cerebral circulation is often difficult to diagnose clinically. We report a case that illustrates the usefulness of transesophageal echocardiography in the detection of paradoxical embolism. An 84-year-old woman presented with bilateral hemispheric strokes. Despite the presence of atrial fi...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2007.01.006

    authors： Iwanaga T,Iguchi Y,Shibazaki K,Inoue T,Kimura K

    更新日期：2007-03-15 00:00:00

  • Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: results from 1-year outcomes in the Japanese REACH Registry.

    abstract：:The REduction of Atherothrombosis for Continued Health (REACH) Registry is a large, international, prospective cohort of patients with atherothrombosis or multiple (>or=3) risk factors (MRFs) for atherothrombosis. Japanese patients (n=5193) were enrolled into the REACH registry between August and December 2004. One-ye...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jns.2009.09.011

    authors： Uchiyama S,Goto S,Matsumoto M,Nagai R,Origasa H,Yamazaki T,Shigematsu H,Shimada K,Yamada N,Bhatt DL,Steg PG,Ikeda Y,REduction of Atherothrombosis for Continued Health Registry Investigators.

    更新日期：2009-12-15 00:00:00

  • Phenomenology and anatomy of abnormal behaviours in primary progressive aphasia.

    abstract：:Primary progressive aphasia (PPA) is a group of disorders with progressive language impairment. Abnormal behaviour may develop in PPA as the disease evolves, but the clinical features and brain basis of behavioural change in PPA have not been fully defined. 33 PPA patients (9 semantic dementia, SD, 14 progressive nonf...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.03.012

    authors： Rohrer JD,Warren JD

    更新日期：2010-06-15 00:00:00

  • Zika virus infection and risk of Guillain-Barré syndrome: A meta-analysis.

    abstract：OBJECTIVE:Findings from studies of the association between Zika virus (ZIKV) infection and Guillain-Barré syndrome (GBS) are inconsistent. I conducted a systematic review and meta-analysis to clarify the nature of this association. METHODS:I searched PubMed, Scopus, Cochrane, CINAHL, Web of Science, Scielo, and DOAJ f...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jns.2019.06.019

    authors： Bautista LE

    更新日期：2019-08-15 00:00:00

  • Diagnostic value of MR imaging in the Lewis-Sumner syndrome: a case series.

    abstract：:Lewis-Sumner syndrome (LSS) is considered a variant of chronic inflammatory demyelinating polyneuropathy (CIDP), which is more frequently described with exclusive upper limb involvement. The diagnosis of LSS is clinical and electrophysiological. However, these are not always obvious and in view of its rarity, the diag...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.04.033

    authors： Rajabally YA,Knopp MJ,Martin-Lamb D,Morlese J

    更新日期：2014-07-15 00:00:00

  • Leigh-like syndrome with the T8993G mutation in the mitochondrial ATPase 6 gene: long-term follow-up discloses a slowly progressive course.

    abstract：:We describe the long-term clinical outcome of a patient with Leigh-like syndrome presenting as an early onset encephalopathy and peripheral neuropathy caused by the T8993G mutation in the mitochondrial DNA (mtDNA). Clinical follow-up for 20 years revealed a peculiar pattern of slow disease progression, characterized b...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2008.11.023

    authors： Sobreira C,Marques W Jr,Pontes Neto OM,Santos AC,Pina Neto JM,Barreira AA

    更新日期：2009-03-15 00:00:00

  • Clinical trials for preventing post stroke cognitive impairment.

    abstract：:Post stroke dementia (PSD) develops in up to 40% of patients and often co-exists with Alzheimer's disease in the elderly. Unsurprisingly, the combination of stroke and dementia is associated with considerable morbidity and mortality, and is devastating to patients and carers. Limited trial evidence suggests that lower...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.08.052

    authors： Ankolekar S,Geeganage C,Anderton P,Hogg C,Bath PM

    更新日期：2010-12-15 00:00:00

  • Usefulness of combining 123I-FP-CIT-SPECT striatal asymmetry index and cardiac 123I-metaiodobenzylguanidine scintigraphy examinations for diagnosis of parkinsonisms.

    abstract：BACKGROUND:Although single-photon emission computerized tomography of the dopamine transporter (DAT-SPECT) is useful for diagnosing parkinsonian syndrome, its applicability toward the early phase of Parkinson's disease remains unknown. METHODS:We enrolled 32 patients showing parkinsonism with normal cardiac 123I-metai...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.04.026

    authors： Niimi Y,Ito S,Murate K,Hirota S,Hikichi C,Ishikawa T,Maeda T,Nagao R,Shima S,Mizutani Y,Ueda A,Mutoh T

    更新日期：2017-06-15 00:00:00

  • Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis.

    abstract：:In recent years it has become clear that multiple sclerosis (MS) patients benefit from physical exercise as performed in aerobic training but little is known about the effect on functional domains and physiological factors mediating these effects. We studied immunological, endocrine and neurotrophic factors as well as...

    journal_title：Journal of the neurological sciences

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jns.2004.06.009

    authors： Schulz KH,Gold SM,Witte J,Bartsch K,Lang UE,Hellweg R,Reer R,Braumann KM,Heesen C

    更新日期：2004-10-15 00:00:00

  • Perampanel as adjunctive therapy in highly refractory epilepsies: Real-world data from an Italian tertiary care epilepsy centre.

    abstract：:Perampanel (PER) is a selective non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonist, licensed as adjunctive therapy in focal epilepsy and primary generalized tonic-clonic seizures (pGTCSs). We performed a retrospective study on highly refractory adult patients taking PER, w...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2018.04.017

    authors： Morano A,Fattouch J,Albini M,Casciato S,Fanella M,Basili LM,Viganò A,Manfredi M,Giallonardo AT,Di Bonaventura C

    更新日期：2018-07-15 00:00:00

  • Gray matter atrophy and disability progression in patients with early relapsing-remitting multiple sclerosis: a 5-year longitudinal study.

    abstract：:We assessed the relationship between gray matter (GM) and white matter (WM) atrophy and clinical status in early relapsing-remitting multiple sclerosis (MS) patients over 5 years. A group of 181 patients who participated in the ASA (Avonex-Steroid-Azathioprine) study and had complete clinical and MRI assessments over ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jns.2008.12.005

    authors： Horakova D,Dwyer MG,Havrdova E,Cox JL,Dolezal O,Bergsland N,Rimes B,Seidl Z,Vaneckova M,Zivadinov R

    更新日期：2009-07-15 00:00:00

  • Investigation and clinical applications of muscle strength change in cerebrospinal fluid tap test in cases of idiopathic normal pressure hydrocephalus: A retrospective study.

    abstract：:The cerebrospinal fluid tap test (CSFTT) is widely used to diagnose idiopathic normal pressure hydrocephalus (iNPH) and predict the therapeutic effectiveness of shunting. However, the ability to walk cannot be quantified for patients who are unable to walk. Therefore, we examined whether the iNPH diagnostic aid is pos...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.10.009

    authors： Matsuoka T,Iida JI,Kawahara M,Uchiyama Y

    更新日期：2016-12-15 00:00:00

  • The characteristics of spinal imaging in different types of demyelinating diseases.

    abstract：BACKGROUND:Transverse myelitis is the common presentation in demyelinating conditions. OBJECTIVE:To determine the characteristics of spinal lesions among each type of demyelinating diseases. METHODS:Medical records and spinal imaging of patients who were [1] older than 18years, [2] had at least one attack of TM, [3] ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.11.035

    authors： Dumrikarnlert C,Siritho S,Chulapimphan P,Ngamsombat C,Satukijchai C,Prayoonwiwat N

    更新日期：2017-01-15 00:00:00

  • Neuropathology of sporadic amyotrophic lateral sclerosis of long duration.

    abstract：:We performed post-mortem examinations of three patients with progressive neurogenic amyotrophy of long duration. One patient had been clinically diagnosed as having sporadic amyotrophic lateral sclerosis (ALS) and two had been diagnosed with progressive spinal muscular atrophy (PSMA). The disease durations were 10, 17...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(96)00297-3

    authors： Iwanaga K,Hayashi S,Oyake M,Horikawa Y,Hayashi T,Wakabayashi M,Kondo H,Tsuji S,Takahashi H

    更新日期：1997-03-10 00:00:00

  • Epstein-Barr virus and multiple sclerosis.

    abstract：:Epstein-Barr virus (EBV) is a human DNA herpesvirus infecting more than 90% of the world's population. EBV is the etiological agent of infectious mononucleosis (Pfeiffer's disease). Furthermore, diverse malignancies such as Burkitt and Hodgkin lymphoma have been associated with EBV. More recently, a possible role for ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2009.03.028

    authors： Pohl D

    更新日期：2009-11-15 00:00:00

  • Occurrence of multiple Cerebral Cavernous Malformations in a patient with Neurofibromatosis type 1.

    abstract：BACKGROUND:Neurofibromatosis 1 (NF1) belongs to the autosomal dominant neurocutaneous disorders' group, which mainly includes NF1 and NF2, tuberous sclerosis, von Hippel-Lindau disease and Cerebral Cavernous Malformations (CCMs). NF1 has a major impact on the nervous system, eye, skin, bone or cardiovascular system. Ce...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.02.023

    authors： Rerat K,Parker F,Nasser G,Vidaud D,Riant F,Tournier-Lasserve E,Denier C

    更新日期：2015-03-15 00:00:00

  • Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model.

    abstract：:The rat double-SAH model is one of the standard models to simulate delayed cerebral vasospasm (CVS) in humans. However, the proof of delayed ischemic brain damage is missing so far. Our objective was, therefore, to determine histological changes in correlation with the development of symptomatic and perfusion weighted...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.03.023

    authors： Güresir E,Raabe A,Jaiimsin A,Dias S,Raab P,Seifert V,Vatter H

    更新日期：2010-06-15 00:00:00

  • Early-onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.

    abstract：:Familial hemiplegic migraine type 1, spinocerebellar ataxia type 6 (SCA6) and episodic ataxia type 2 (EA2) are allelic disorders associated with mutations in the CACNA1A gene, which encodes the alpha1 subunit of the P/Q-type calcium channel (Ca(V)2.1). SCA6 and EA2 share a number of clinical features, such as prominen...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2007.01.008

    authors： Cricchi F,Di Lorenzo C,Grieco GS,Rengo C,Cardinale A,Racaniello M,Santorelli FM,Nappi G,Pierelli F,Casali C

    更新日期：2007-03-15 00:00:00

  • Prevalence of migraine headache and its weight on neurological burden in Africa: a 43-year systematic review and meta-analysis of community-based studies.

    abstract：BACKGROUND:Headache burden is not adequately explored in Africa. Here, we measured weighted migraine prevalence from community-based studies in Africa. METHODS:PubMed search was employed using terms 'headache in Africa' AND/OR 'migraine in Africa' for published literature from 1970 until January 31, 2014. PRISMA was a...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jns.2014.04.019

    authors： Woldeamanuel YW,Andreou AP,Cowan RP

    更新日期：2014-07-15 00:00:00

  • Dynamic changes of focal hypometabolism in relation to epileptic activity.

    abstract：:The interictal hypometabolism in patients with focal epilepsy is usually regarded as stationary. In this study we investigated to which extent the hypometabolism may depend on the activity of the epileptic focus. In focal penicillin-induced epilepsy in rats the epileptic focus is hypermetabolic. This focus is accompan...

    journal_title：Journal of the neurological sciences

    pub_type： 临床试验,杂志文章

    doi：10.1016/0022-510x(94)90325-5

    authors： Witte OW,Bruehl C,Schlaug G,Tuxhorn I,Lahl R,Villagran R,Seitz RJ

    更新日期：1994-07-01 00:00:00

  • COVID-19 in multiple sclerosis patients and risk factors for severe infection.

    abstract：:Multiple sclerosis (MS) patients have been considered a higher-risk population for COVID-19 due to the high prevalence of disability and disease-modifying therapy use; however, there is little data identifying clinical characteristics of MS associated with worse COVID-19 outcomes. Therefore, we conducted a multicenter...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jns.2020.117147

    authors： Chaudhry F,Bulka H,Rathnam AS,Said OM,Lin J,Lorigan H,Bernitsas E,Rube J,Korzeniewski SJ,Memon AB,Levy PD,Schultz L,Javed A,Lisak R,Cerghet M

    更新日期：2020-11-15 00:00:00

  • Poor recovery after the first two attacks of multiple sclerosis is associated with poor outcome five years later.

    abstract：OBJECTIVE:Examine the relative importance of several risk factors for progression, in a large sample of MS patients. METHODS:Using a retrospective design in a single university-based MS treatment center, we studied 207 patients with relapsing remitting MS diagnosed, treated at our center, evaluated within one year of ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.02.008

    authors： Scott TF,Schramke CJ

    更新日期：2010-05-15 00:00:00

  • LINGO1 and risk for essential tremor: results of a meta-analysis of rs9652490 and rs11856808.

    abstract：BACKGROUND/OBJECTIVES:Recently, a genome-wide association study revealed a significant statistical association between LINGO1 rs9652490 and rs11856808 polymorphisms and the risk of developing essential tremor (ET) in Icelandic people. Because the results of further association studies were controversial, we conducted a...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jns.2012.02.030

    authors： Jiménez-Jiménez FJ,García-Martín E,Lorenzo-Betancor O,Pastor P,Alonso-Navarro H,Agúndez JA

    更新日期：2012-06-15 00:00:00

  • Inclusion body myositis: peripheral nerve involvement. Combined morphological and electrophysiological studies on peripheral nerves.

    abstract：:The occurrence of neuropathy in 5 cases of inclusion body myositis (IBM) was studied. The intramuscular nerve branches showed variable ultrastructural changes in all cases. The observed changes were loss of axons, wallerian degeneration and axon terminal atrophy. EMG with concentric needles showed myopathic motor unit...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(90)90167-l

    authors： Lindberg C,Oldfors A,Hedström A

    更新日期：1990-11-01 00:00:00

  • Enhanced inflammatory response via activation of NF-kappaB in acute experimental diabetic neuropathy subjected to ischemia-reperfusion injury.

    abstract：:Reperfusion following ischemia increases ischemic fiber degeneration (IFD) in diabetic nerves compared to control normoglycemic nerves. The mechanism of this excessive susceptibility is unclear. Since reperfusion injury results in an inflammatory response, we tested the hypothesis that the diabetic state increases the...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2006.03.011

    authors： Wang Y,Schmeichel AM,Iida H,Schmelzer JD,Low PA

    更新日期：2006-08-15 00:00:00

  • Cerebrovascular reactivity after treatment of unruptured intracranial aneurysms--A transcranial Doppler sonography and acetazolamide study.

    abstract：BACKGROUND:Cerebrovascular reactivity (CVR) is defined as the change in cerebral blood flow, or blood velocity, in response to a vasoactive stimulus. There is a possible association between impaired CVR and vasospasm after aneurysmal subarachnoid hemorrhage. Most studies on CVR and vasospasm have used healthy subjects ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.12.024

    authors： Bøthun ML,Haaland ØA,Logallo N,Svendsen F,Thomassen L,Helland CA

    更新日期：2016-04-15 00:00:00