当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Application of a computerized medical decision-making process to the problem of digoxin intoxication.

Application of a computerized medical decision-making process to the problem of digoxin intoxication.

Abstract：

:A computerized medical decision-making system was used to monitor signs and predisposing factors of digoxin intoxication in patients receiving digoxin. This process automatically reviewed the patient's data base nightly for drug interactions, laboratory data and electrocardiographic findings with known association with digoxin intoxication. These decisions were formated into a "digoxin alert report" and sent to line printers in the nursing division to be placed on the individual patients' charts. To assess the effect of these reports on patient management, a randomized double-blind study was undertaken. Patients were assigned to an alert or nonalert group. Alert reports were withheld from charts of patients in the nonalert group. A medical record review was subsequently carried out, wherein the physician's orders were searched to identify actions taken with possible relation to the digoxin alerts. The computer monitored 396 patients over a 3 month period. Of these, 211 (53%) were randomized to the alert group and 185 (47%) to the nonalert group. Seventy-two percent of patients received at least one alert. The most frequently occurring alerts included: hypoxemia, hypokalemia, concurrent use of a beta-adrenergic blocking agent, renal insufficiency and ventricular arrhythmia. Results from the record review demonstrated a 22% increase in physician actions for the alert group. Specifically, patients in the alert group were 2.7 times more likely to have a serum digoxin determination ordered and 2.8 times more likely to have digoxin withheld on the day of a digoxin alert than were patients in the nonalert group.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

White KS,Lindsay A,Pryor TA,Brown WF,Walsh K

doi

10.1016/s0735-1097(84)80104-7

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

571-6

issue

3

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(84)80104-7

journal_volume

4

pub_type

临床试验,杂志文章,随机对照试验

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Recurrent unexplained palpitations (RUP) study comparison of implantable loop recorder versus conventional diagnostic strategy.

    abstract：OBJECTIVES:The aim of the study was to compare the diagnostic yield and the costs of implantable loop recorder (ILR) with those of the conventional strategy in patients with unexplained palpitations. BACKGROUND:In patients with unexplained palpitations, especially in those with infrequent symptoms, the conventional st...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2007.02.036

    authors： Giada F,Gulizia M,Francese M,Croci F,Santangelo L,Santomauro M,Occhetta E,Menozzi C,Raviele A

    更新日期：2007-05-15 00:00:00

  • Electromagnetic interference from welding and motors on implantable cardioverter-defibrillators as tested in the electrically hostile work site.

    abstract：OBJECTIVES:This study was designed to determine the susceptibility of an implanted cardioverter-defibrillator to electromagnetic interference in an electrically hostile work site environment, with the ultimate goal of allowing the patient to return to work. BACKGROUND:Normal operation of an implanted cardioverter-defi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(96)00147-7

    authors： Fetter JG,Benditt DG,Stanton MS

    更新日期：1996-08-01 00:00:00

  • Long-term prognosis of patients with anginalike chest pain and normal coronary angiographic findings.

    abstract：OBJECTIVES:This study analyzes the long-term course of patients with typical angina pectoris or anginalike chest pain and normal coronary angiographic findings. BACKGROUND:In previous studies of such patients the rate of occurrence of typical coronary events during follow-up has differed widely, depending on the durat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)00519-v

    authors： Lichtlen PR,Bargheer K,Wenzlaff P

    更新日期：1995-04-01 00:00:00

  • Public reporting of clinical quality data: an update for cardiovascular specialists.

    abstract：:Public reporting of hospital and individual provider quality of care measures is not a new concept. In the United States, the first national public reports of hospital mortality data occurred in 1986, and detailed physician-level data for cardiac surgery are now reported in 4 states. The development of the "Hospital C...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2013.11.050

    authors： Dehmer GJ,Drozda JP Jr,Brindis RG,Masoudi FA,Rumsfeld JS,Slattery LE,Oetgen WJ

    更新日期：2014-04-08 00:00:00

  • Predictors of inducible sustained ventricular tachyarrhythmias in patients with coronary artery disease.

    abstract：:To determine predictors of inducible sustained ventricular tachycardia or fibrillation by programmed electrical stimulation in patients with coronary artery disease and ventricular tachyarrhythmias, 14 clinical and angiographic variables were analyzed in 60 consecutive patients. All patients had angiographically docum...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(89)90605-0

    authors： Vorperian VR,Gittelsohn AM,Veltri EP

    更新日期：1989-03-01 00:00:00

  • Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-Related Mortality in U.S. Adults.

    abstract：BACKGROUND:Previous studies have revealed inconsistent findings regarding the association of light to moderate alcohol consumption with cardiovascular disease (CVD) and cancer mortality. OBJECTIVES:The aim of this study was to examine the association between alcohol consumption and risk of mortality from all causes, c...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jacc.2017.06.054

    authors： Xi B,Veeranki SP,Zhao M,Ma C,Yan Y,Mi J

    更新日期：2017-08-22 00:00:00

  • 10-year exercise training in chronic heart failure: a randomized controlled trial.

    abstract：OBJECTIVES:This study investigated the effect of a very long-term exercise training program is not known in chronic heart failure (CHF) patients. BACKGROUND:We previously showed that long-term moderate exercise training (ET) improves functional capacity and quality of life in New York Heart Association class II and II...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2012.06.036

    authors： Belardinelli R,Georgiou D,Cianci G,Purcaro A

    更新日期：2012-10-16 00:00:00

  • Transient sinus node dysfunction after the Cox-maze III procedure in patients with organic heart disease and chronic fixed atrial fibrillation.

    abstract：OBJECTIVES:This prospective study examined types, frequency and time dependency of the electrophysiologic manifestation of the sinus node dysfunction after the Cox-maze III procedure--the technique of choice for the management of medically refractory atrial fibrillation-in patients with organic heart disease, chronic f...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00358-1

    authors： Pasic M,Musci M,Siniawski H,Edelmann B,Tedoriya T,Hetzer R

    更新日期：1998-10-01 00:00:00

  • Likelihood of spontaneous conversion of atrial fibrillation to sinus rhythm.

    abstract：OBJECTIVES:We sought to determine the likelihood and predictors of spontaneous conversion to sinus rhythm of recent-onset atrial fibrillation (symptoms <72 h). BACKGROUND:Although spontaneous conversion of recent-onset atrial fibrillation is common, the likelihood and clinical and echocardiographic predictors have not...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(97)00534-2

    authors： Danias PG,Caulfield TA,Weigner MJ,Silverman DI,Manning WJ

    更新日期：1998-03-01 00:00:00

  • Unexpected deviation in circadian variation of ventricular arrhythmias: the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial).

    abstract：OBJECTIVES:This study sought to determine whether circadian patterns in ventricular arrhythmias (VAs) occur in a current primary prevention defibrillator (implantable cardioverter-defibrillator [ICD]) population. BACKGROUND:Cardiovascular events, including VAs, demonstrate biorhythmic periodicity. METHODS:We tested f...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2013.11.072

    authors： Patton KK,Hellkamp AS,Lee KL,Mark DB,Johnson GW,Anderson J,Bardy GH,Poole JE,SCD-HeFT Investigators.

    更新日期：2014-06-24 00:00:00

  • Low energy synchronous transcatheter cardioversion of atrial flutter/fibrillation in the dog.

    abstract：:The feasibility and effectiveness of low energy synchronous transcatheter cardioversion of atrial flutter and fibrillation were examined in dogs with talc-induced pericarditis. A conventional electrode catheter was positioned transvenously in the right atrial appendage. Atrial flutter/fibrillation was induced by using...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(90)90610-2

    authors： Kumagai K,Yamanouchi Y,Tashiro N,Hiroki T,Arakawa K

    更新日期：1990-08-01 00:00:00

  • The World Trade Center attack: increased frequency of defibrillator shocks for ventricular arrhythmias in patients living remotely from New York City.

    abstract：OBJECTIVES:The goal of this study was to determine whether the World Trade Center (WTC) attack on September 11, 2001, had an effect on the occurrence of ventricular arrhythmias among patients with implantable cardioverter-defibrillators (ICDs) living in Florida. BACKGROUND:Increased frequencies of ICD therapies for ve...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2004.04.058

    authors： Shedd OL,Sears SF Jr,Harvill JL,Arshad A,Conti JB,Steinberg JS,Curtis AB

    更新日期：2004-09-15 00:00:00

  • Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial.

    abstract：OBJECTIVES:The purpose of this study is to evaluate the efficacy and safety of ticagrelor and clopidogrel in patients with acute coronary syndrome undergoing coronary artery bypass graft surgery (CABG), as a post-randomization strategy. BACKGROUND:Ticagrelor is a novel, reversibly binding, oral, direct-acting P2Y(12)-...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jacc.2010.10.029

    authors： Held C,Asenblad N,Bassand JP,Becker RC,Cannon CP,Claeys MJ,Harrington RA,Horrow J,Husted S,James SK,Mahaffey KW,Nicolau JC,Scirica BM,Storey RF,Vintila M,Ycas J,Wallentin L

    更新日期：2011-02-08 00:00:00

  • Effect of aspirin on late preconditioning against myocardial stunning in conscious rabbits.

    abstract：OBJECTIVES:The goal of this study was to investigate the effect of three different doses of acetylsalicylic acid (aspirin) (ASA) on the late phase of ischemic preconditioning (PC) against myocardial stunning. BACKGROUND:Although recent evidence indicates that the late phase of ischemic PC is mediated by cyclooxygenase...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(03)00086-x

    authors： Shinmura K,Kodani E,Xuan YT,Dawn B,Tang XL,Bolli R

    更新日期：2003-04-02 00:00:00

  • Pulmonary artery growth after palliation of congenital heart disease with duct-dependent pulmonary circulation: arterial duct stenting versus surgical shunt.

    abstract：OBJECTIVES:The aim of this study was to compare the pulmonary artery (PA) growth after arterial duct (AD) stenting versus modified Blalock-Taussig shunt (MBTS) in neonates with congenital heart disease with duct-dependent pulmonary circulation (CHD-DPC). BACKGROUND:Arterial duct stenting is increasingly deemed a relia...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2009.07.043

    authors： Santoro G,Capozzi G,Caianiello G,Palladino MT,Marrone C,Farina G,Russo MG,Calabrò R

    更新日期：2009-12-01 00:00:00

  • Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.

    abstract：OBJECTIVES:We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study. BACKGROUND:Full adrenergic blockade by carvedilol and additional (e.g., antiox...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2006.10.059

    authors： Remme WJ,Torp-Pedersen C,Cleland JG,Poole-Wilson PA,Metra M,Komajda M,Swedberg K,Di Lenarda A,Spark P,Scherhag A,Moullet C,Lukas MA

    更新日期：2007-03-06 00:00:00

  • Erythropoietin receptor signaling mitigates renal dysfunction-associated heart failure by mechanisms unrelated to relief of anemia.

    abstract：OBJECTIVES:We examined the effect of asialoerythropoietin (asialoEPO), a nonerythrogenic derivative of erythropoietin (EPO), on renal dysfunction-associated heart failure. BACKGROUND:Although EPO is known to exert beneficial effects on cardiac function, the clinical benefits in patients with chronic kidney disease are...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2010.04.068

    authors： Ogino A,Takemura G,Kawasaki M,Tsujimoto A,Kanamori H,Li L,Goto K,Maruyama R,Kawamura I,Takeyama T,Kawaguchi T,Watanabe T,Moriguchi Y,Saito H,Fujiwara T,Fujiwara H,Minatoguchi S

    更新日期：2010-11-30 00:00:00

  • Impact of cardiac resynchronization therapy using hemodynamically optimized pacing on left ventricular remodeling in patients with congestive heart failure and ventricular conduction disturbances.

    abstract：OBJECTIVES:We sought to investigate the impact of six months of cardiac resynchronization therapy (CRT) on echocardiographic variables of left ventricular (LV) function. BACKGROUND:Cardiac resynchronization therapy has recently been introduced as a new therapeutic modality in patients with advanced heart failure (HF) ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(01)01637-0

    authors： Stellbrink C,Breithardt OA,Franke A,Sack S,Bakker P,Auricchio A,Pochet T,Salo R,Kramer A,Spinelli J,PATH-CHF (PAcing THerapies in Congestive Heart Failure) Investigators; CPI Guidant Congestive Heart Failure Research Group.

    更新日期：2001-12-01 00:00:00

  • Nitric oxide inhibition impairs blood flow during exercise in hearts with a collateral-dependent myocardial region.

    abstract：OBJECTIVES:We sought to determine the importance of nitric oxide (NO) production in maintaining coronary blood flow during exercise in hearts with collateral-dependent myocardium. BACKGROUND:Coronary collateral vessels demonstrate endothelium-mediated NO-dependent vasodilation in response to agonists such as acetylcho...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(97)00437-3

    authors： Traverse JH,Kinn JW,Klassen C,Duncker DJ,Bache RJ

    更新日期：1998-01-01 00:00:00

  • Ability of troponin I to predict cardiac events in patients admitted from the emergency department.

    abstract：OBJECTIVES:We sought to determine the predictive ability of troponin I (TnI) in a heterogeneous group of patients with chest pain admitted from the emergency department (ED) for exclusion of myocardial infarction (MI). BACKGROUND:Previous studies in high-risk patients demonstrated that troponin elevations are associat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 评论,杂志文章

    doi：10.1016/s0735-1097(00)00943-8

    authors： Kontos MC,Anderson FP,Alimard R,Ornato JP,Tatum JL,Jesse RL

    更新日期：2000-11-15 00:00:00

  • Oxidative stress and pathological changes after coronary artery interventions.

    abstract：:Oxidative stress greatly influences the pathogenesis of various cardiovascular disorders. Coronary interventions, including balloon angioplasty and coronary stent implantation, are associated with increased vascular levels of reactive oxygen species in conjunction with altered endothelial cell and smooth muscle cell f...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2012.11.068

    authors： Juni RP,Duckers HJ,Vanhoutte PM,Virmani R,Moens AL

    更新日期：2013-04-09 00:00:00

  • Antithrombotics: From Aspirin to DOACs in Coronary Artery Disease and Atrial Fibrillation (Part 3/5).

    abstract：:For secondary prevention of coronary artery disease (CAD), oral antiplatelet therapy is essential. In case of coronary intervention, temporary dual antiplatelet therapy is mandatory as well. Recently, low-dose oral anticoagulation has entered the CAD arena. Atrial fibrillation (AF) is often seen in CAD and vice versa....

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2019.02.080

    authors： Verheugt FWA,Ten Berg JM,Storey RF,Cuisset T,Granger CB

    更新日期：2019-08-06 00:00:00

  • Antithrombotic therapy in patients with valvular heart disease and prosthetic heart valves.

    abstract：:Indications and the type of antithrombotic therapy for the prevention of thromboembolism in patients with valvular heart disease, mechanical prosthetic heart valves and bioprosthetic heart valves are discussed. The evidence for these clinical recommendations is described and graded into five levels. The indications fo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/s0735-1097(86)80006-7

    authors： Chesebro JH,Adams PC,Fuster V

    更新日期：1986-12-01 00:00:00

  • Importance of estimated functional capacity as a predictor of all-cause mortality among patients referred for exercise thallium single-photon emission computed tomography: report of 3,400 patients from a single center.

    abstract：OBJECTIVES:We sought to determine the relative influence of estimated functional capacity and thallium-201 (Tl-201) single-photon emission computed tomographic (SPECT) findings on prediction of short-term all-cause and cardiac-related mortality. BACKGROUND:Decreased functional capacity and abnormal Tl-201 SPECT findin...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(97)00217-9

    authors： Snader CE,Marwick TH,Pashkow FJ,Harvey SA,Thomas JD,Lauer MS

    更新日期：1997-09-01 00:00:00

  • Combined use of warfarin and adjusted subcutaneous heparin during pregnancy in patients with an artificial heart valve.

    abstract：:Adjusted subcutaneous heparin was used for thromboembolism prophylaxis during 18 pregnancies in 16 women with an artificial heart valve. Oral warfarin was replaced by subcutaneous heparin as soon as pregnancy was confirmed. The dosage of heparin was adjusted to maintain a partial thromboplastin time at 1.5 times the c...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(86)80116-4

    authors： Lee PK,Wang RY,Chow JS,Cheung KL,Wong VC,Chan TK

    更新日期：1986-07-01 00:00:00

  • Differential effects of antihypertensive treatment on left ventricular diastolic function: an ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) substudy.

    abstract：OBJECTIVES:We hypothesized that an amlodipine-based regimen would have more favorable effects on left ventricular (LV) diastolic function. BACKGROUND:Different antihypertensive therapies may vary in their effect on LV diastolic function. METHODS:The HACVD (Hypertension Associated Cardiovascular Disease) substudy of A...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2009.11.084

    authors： Tapp RJ,Sharp A,Stanton AV,O'Brien E,Chaturvedi N,Poulter NR,Sever PS,Thom SA,Hughes AD,Mayet J,ASCOT Investigators.

    更新日期：2010-04-27 00:00:00

  • Gender differences in molecular remodeling in pressure overload hypertrophy.

    abstract：OBJECTIVES:The objective of this study was to examine gender differences in left ventricular (LV) function and expression of cardiac genes in response to LV pressure overload due to ascending aortic stenosis in rats. BACKGROUND:Clinical studies have documented gender differences in the pattern of adaptive LV hypertrop...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(99)00165-5

    authors： Weinberg EO,Thienelt CD,Katz SE,Bartunek J,Tajima M,Rohrbach S,Douglas PS,Lorell BH

    更新日期：1999-07-01 00:00:00

  • Triphasic waveforms are superior to biphasic waveforms for transthoracic defibrillation: experimental studies.

    abstract：OBJECTIVES:Our objective was to evaluate the efficacy of triphasic waveforms for transthoracic defibrillation in a swine model. BACKGROUND:Triphasic shocks have been found to cause less post-shock dysfunction than biphasic shocks in chick embryo studies. METHODS:After 30 s of electrically induced ventricular fibrilla...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(03)00656-9

    authors： Zhang Y,Ramabadran RS,Boddicker KA,Bawaney I,Davies LR,Zimmerman MB,Wuthrich S,Jones JL,Kerber RE

    更新日期：2003-08-06 00:00:00

  • Comparison between transcatheter and surgical closure of secundum atrial septal defect in children and adults: results of a multicenter nonrandomized trial.

    abstract：OBJECTIVES:This study sought to compare the safety, efficacy and clinical utility of the Amplatzer septal occluder (ASO) for closure of secundum atrial septal defect (ASD) with surgical closure. BACKGROUND:The clinical utility of a device such as the ASO can only be judged against the results of contemporaneous surger...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/s0735-1097(02)01862-4

    authors： Du ZD,Hijazi ZM,Kleinman CS,Silverman NH,Larntz K,Amplatzer Investigators.

    更新日期：2002-06-05 00:00:00

  • Prospective two-dimensional echocardiographic evaluation of left ventricular thrombus and embolism after acute myocardial infarction.

    abstract：:To determine whether two-dimensional echocardiography can identify patients with left ventricular thrombus after myocardial infarction who are prone to embolism, clinical and echocardiographic variables in 541 patients with a first infarction between 1979 and 1983 were studied prospectively. The first echocardiogram s...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(89)90592-5

    authors： Jugdutt BI,Sivaram CA

    更新日期：1989-03-01 00:00:00