Changes in corneal sensitivity following cross-linking for progressive early-stage keratoconus.

Abstract:

PURPOSE:To evaluate changes in corneal sensitivity following corneal cross-linking (CXL) in patients with progressive earlier stage keratoconus. METHODS:Thirty-eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. The mean patient age was 22 years (range, 18-26 years). Inclusion criteria were early stage bilateral progressive keratoconus, a transparent cornea, and a thickness of ≥440 µm in the thinnest area of the cornea. Using the Cochet-Bonnet esthesiometer, central corneal sensitivity was measured before surgery, 7 days after surgery, and once a month thereafter until recovery of baseline preoperative levels. Central corneal sensitivity >40 mm was considered normal. RESULTS:Corneal sensitivity gradually returned to preoperative levels in all treated eyes. The mean central corneal sensitivity was 52.2, 24.0, 38.2, 42.5, 50.0, and 52.5 mm before surgery, 7 days after surgery, and at 1, 2, 3, and 4 months after surgery, respectively. Normal levels of corneal sensation, but not baseline (preoperative) levels, were observed 2 months after surgery. The preoperative levels were observed 3 months after surgery. CONCLUSIONS:Our results suggest that central corneal sensitivity can be decreased for as long as 3 months after CXL for progressive earlier stage keratoconus.

journal_name

Arq Bras Oftalmol

authors

Lago Ade M,Nassaralla BR,Stival LR,Nassaralla Junior JJ

doi

10.5935/0004-2749.20140021

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

84-7

issue

2

eissn

0004-2749

issn

1678-2925

pii

S0004-27492014000200084

journal_volume

77

pub_type

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