The relationship between topical anti-glaucoma medications and the development of lacrimal drainage system obstruction.

Abstract:

PURPOSE:To evaluate whether any topical anti-glaucoma medications increase the risk of lacrimal drainage system obstruction or whether the presence of preservatives alone is sufficient to generate obstruction. METHODS:This nested case-control study compared a group of patients with lacrimal duct obstruction who received topical anti-glaucoma medications to a control group of patients without obstruction. RESULTS:The medical records of 255 patients with glaucoma who consulted the Oculoplastic Section with complaints of watery eyes were reviewed. Among these patients, 59 exhibited lacrimal drainage obstruction. Ninety-four percent of patients with lacrimal drainage obstruction used beta-blockers, and 41% used prostaglandin analogs. A logistic regression model was used to adjust for age, sex, and the use of other medications. No significant differences were observed regarding the topical anti-glaucoma medications used between groups. CONCLUSION:No single topical anti-glaucoma medication demonstrated a stronger association with the development of lacrimal duct obstruction.

journal_name

Arq Bras Oftalmol

authors

Ortiz-Basso T,Galmarini A,Vigo RL,Gonzalez-Barlatay JM,Premoli EJ

doi

10.5935/0004-2749.20180095

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

490-493

issue

6

eissn

0004-2749

issn

1678-2925

pii

S0004-27492018005002103

journal_volume

81

pub_type

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