Piperacillin versus clindamycin plus gentamicin for pelvic infections.

Abstract:

:Piperacillin, a new semisynthetic penicillin, has broad spectrum activity against most clinically important aerobic and anaerobic bacteria. In the present study, piperacillin was compared with a combination of clindamycin and gentamicin for the treatment of 83 women with pelvic infection (42 with endometritis, 29 with posthysterectomy cuff infections, 11 with acute salpingitis, and one with a wound infection). There were 179 bacterial isolates, 98 (53%) aerobic and 81 (45%) anaerobic. Of the 42 patients treated with piperacillin, there were three (7.1%) clinical failures compared with one (2.4%) in the 41 patients treated with clindamycin-gentamicin. A single drug, piperacillin, was shown to be as safe and effective as the combined clindamycin plus gentamicin therapy for pelvic infections.

journal_name

Obstet Gynecol

authors

Gilstrap LC 3rd,Maier RC,Gibbs RS,Connor KD,St Clair PJ

subject

Has Abstract

pub_date

1984-12-01 00:00:00

pages

762-6

issue

6

eissn

0029-7844

issn

1873-233X

journal_volume

64

pub_type

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