Adaptation to lateral displacement of vision in patients with lesions of the central nervous system.

abstract：BACKGROUND:The APOE epsilon4 allele has emerged as a major genetic factor for Alzheimer disease (AD), and its presence has been associated with an increase in beta-amyloid senile plaques (SPs) and neuritic plaques (NPs). Whether it affects neurofibrillary tangle (NFT) accumulation or cholinergic losses in AD remains co...

journal_title：Neurology

authors： Tiraboschi P,Hansen LA,Masliah E,Alford M,Thal LJ,Corey-Bloom J

更新日期：2004-06-08 00:00:00

abstract：:Butyrylcholinesterase is implicated in the pathology of AD. Selective inhibitors increase acetylcholine and improve cognitive function in animal models. In dementia with Lewy bodies, cholinergic activities are more affected than in AD. The authors report a highly significant association between temporal cortex butyryl...

journal_title：Neurology

authors： Perry E,McKeith I,Ballard C

更新日期：2003-06-10 00:00:00

abstract：OBJECTIVE:To describe neural autoantibody profiles and outcomes in patients with neurologic autoimmunity associated with immune checkpoint inhibitor (ICI) cancer immunotherapy. METHODS:In this retrospective descriptive study, 63 patients with ICI-related neurologic autoimmunity were included: 39 seen at the Mayo Clini...

journal_title：Neurology

authors： Sechi E,Markovic SN,McKeon A,Dubey D,Liewluck T,Lennon VA,Lopez-Chiriboga AS,Klein CJ,Mauermann M,Pittock SJ,Flanagan EP,Zekeridou A

更新日期：2020-10-27 00:00:00

abstract：OBJECTIVES:To assess the therapeutic efficacy, required dose, and tolerability of pregabalin in patients with idiopathic restless legs syndrome (RLS). METHODS:This was a double-blind, placebo-controlled trial with polysomnographic control, providing Class II evidence. Ninety-eight patients underwent a 2-week single-bl...

journal_title：Neurology

authors： Garcia-Borreguero D,Larrosa O,Williams AM,Albares J,Pascual M,Palacios JC,Fernandez C

更新日期：2010-06-08 00:00:00

abstract：OBJECTIVE:This study aimed to determine the frequency of CNS infection by dengue virus (DENV) in individuals with fatal outcomes. METHODS:Samples of 150 individuals suspect of an infection disease and with fatal outcomes were investigated for evidence of the presence of DENV. The sampling was made up of 150 CSF, 120 t...

journal_title：Neurology

authors： Araújo FM,Araújo MS,Nogueira RM,Brilhante RS,Oliveira DN,Rocha MF,Cordeiro RA,Araújo RM,Sidrim JJ

更新日期：2012-03-06 00:00:00

abstract：:A group of 204 muscular dystrophy patients were screened for immunohistochemical and biochemical alpha-sarcoglycan defect and their DNA was analyzed for pathogenetic mutation in the four sarcoglycan genes. We identified 21 patients with alpha-, beta-, or gamma-sarcoglycan gene mutations. Patients with alpha-sarcoglyca...

journal_title：Neurology

authors： Angelini C,Fanin M,Freda MP,Duggan DJ,Siciliano G,Hoffman EP

更新日期：1999-01-01 00:00:00

abstract：:A 3-year old, previously well child developed paroxysms of left thigh pain. Evaluation was unremarkable except for interictal and postictal EEG epileptiform activity in the right parietal and posterior temporal regions. The painful spells were controlled with anticonvulsant medication. Episodes of paroxysmal, unexplai...

journal_title：Neurology

authors： Trevathan E,Cascino GD

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested a variety of factors that may be associated with the presence of hippocampal formation (HF) atrophy in patients with complex partial seizures (CPS), including a history of complex or prolonged febrile seizures (FS), age at seizure onset, and epilepsy duration. OBJECTIVE:To de...

journal_title：Neurology

authors： Theodore WH,Bhatia S,Hatta J,Fazilat S,DeCarli C,Bookheimer SY,Gaillard WD

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To assess the effect of patient and drug characteristics on medication adherence in people with epilepsy (PWE) in a large cohort representative of the German population. METHODS:Information was obtained from the Disease Analyzer database that collects anonymous demographic and medical data from practice comp...

journal_title：Neurology

authors： Gollwitzer S,Kostev K,Hagge M,Lang J,Graf W,Hamer HM

更新日期：2016-08-02 00:00:00

abstract：OBJECTIVE:To investigate whether plasma interleukin-6 (IL-6) is cross-sectionally related to poorer cognitive function and whether a baseline plasma IL-6 measurement can predict risk for decline in cognitive function in longitudinal follow-up of a population-based sample of nondisabled elderly people. METHODS:A prospe...

journal_title：Neurology

authors： Weaver JD,Huang MH,Albert M,Harris T,Rowe JW,Seeman TE

更新日期：2002-08-13 00:00:00

abstract：:We examined six patients with an abrupt change in behavior after infarction involving the inferior genu of the internal capsule. The acute syndrome featured fluctuating alertness, inattention, memory loss, apathy, abulia, and psychomotor retardation, suggesting frontal lobe dysfunction. Contralateral hemiparesis and d...

journal_title：Neurology

authors： Tatemichi TK,Desmond DW,Prohovnik I,Cross DT,Gropen TI,Mohr JP,Stern Y

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To describe a new familial association of late-onset dementia, patchy leukoencephalopathy, intracerebral hemorrhages, bilateral occipital calcifications (BOC), and external carotid artery dysplasia (ECAD). METHODS:At age 62, the proband, who was of Spanish descent, had left temporal hemorrhage in a backgroun...

journal_title：Neurology

authors： Iglesias S,Chapon F,Baron JC

更新日期：2000-12-12 00:00:00

abstract：:We report a family with Machado-Joseph disease (MJD) that was previously diagnosed with dentatorubral-pallidoluysian atrophy (DRPLA), on the basis of the neuropathologic findings. Because the clinical and pathologic reevaluation strongly suggested a diagnosis of MJD, we conducted a genetic study in the family. Two pat...

journal_title：Neurology

authors： Sakai T,Antoku Y,Kawakami H,Maruyama H,Nakamura S,Tanaka K

更新日期：1996-04-01 00:00:00

abstract：:We prospectively evaluated the relationship between a common psychological stressor and relapses in multiple sclerosis (MS) in a group of 32 MS patients exposed to the threat of missile attacks during the Persian Gulf War of 1991. The number of relapses during the war and the following 2 months was significantly lower...

journal_title：Neurology

authors： Nisipeanu P,Korczyn AD

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of ocular motor information in the early diagnosis of corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP). METHODS:Seven PSP patients, six CBD patients, and three atypical CBD patients were followed longitudinally with repeated electrooculographic (EOG) recordi...

journal_title：Neurology

authors： Rivaud-Péchoux S,Vidailhet M,Gallouedec G,Litvan I,Gaymard B,Pierrot-Deseilligny C

更新日期：2000-03-14 00:00:00

abstract：:Three children with cerebral oligodendrogliomas causing partial complex or generalized seizures presented with completely normal neurologic examinations. CT showed low-density, nonenhancing surface lesions. Although these CT features are usually associated with infarcts or cysts, neoplasm was suspected because of irre...

journal_title：Neurology

authors： Varma RR,Crumrine PK,Bergman I,Latchaw RE,Price RA,Vries J,Painter MJ

更新日期：1983-06-01 00:00:00

abstract：:Human cytomegalovirus and herpes simplex virus DNA probes were labeled in vitro and hybridized to the DNA extracted from brains of patients with multiple sclerosis (MS) to detect the presence of genetic information related to these viruses. We were unable to detect any virus-related genetic information complementary t...

journal_title：Neurology

authors： Aulakh GS,Albrecht P,Tourtellotte WW

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:To evaluate the time course of major vessel recanalization under IV thrombolysis in relation to functional outcome in acute ischemic stroke. METHODS:A total of 99 patients with an acute anterior circulation vessel occlusion who underwent IV thrombolysis were included. All patients had a standardized admissi...

journal_title：Neurology

authors： Wunderlich MT,Goertler M,Postert T,Schmitt E,Seidel G,Gahn G,Samii C,Stolz E,Duplex Sonography in Acute Stroke (DIAS) Study Group.,Competence Network Stroke.

更新日期：2007-04-24 00:00:00

abstract：OBJECTIVE:The gradual development of cutaneous allodynia during the course of a migraine attack is commonly detected by quantitative sensory testing (QST) in migraineurs seeking secondary and tertiary medical help. In this study, the authors developed a questionnaire that tested the recollection of the patients on thei...

journal_title：Neurology

authors： Jakubowski M,Silberstein S,Ashkenazi A,Burstein R

更新日期：2005-11-08 00:00:00

abstract：OBJECTIVE:To assess the role of CHCHD2 variants in patients with Parkinson disease (PD) and Lewy body disease (LBD) in Caucasian populations. METHODS:All exons of the CHCHD2 gene were sequenced in a US Caucasian patient-control series (878 PD, 610 LBD, and 717 controls). Subsequently, exons 1 and 2 were sequenced in a...

journal_title：Neurology

authors： Ogaki K,Koga S,Heckman MG,Fiesel FC,Ando M,Labbé C,Lorenzo-Betancor O,Moussaud-Lamodière EL,Soto-Ortolaza AI,Walton RL,Strongosky AJ,Uitti RJ,McCarthy A,Lynch T,Siuda J,Opala G,Rudzinska M,Krygowska-Wajs A,Barcikowska

更新日期：2015-12-08 00:00:00

abstract：OBJECTIVE:The authors investigated chronic cerebellar reorganization following unilateral cortical lesions in children and adults using PET to measure benzodiazepine receptor (BZR) binding with [11C]flumazenil (FMZ) and glucose metabolism with 2-deoxy-2[18F]fluoro-D-glucose (FDG). BACKGROUND:Crossed cerebellar diaschi...

journal_title：Neurology

authors： Niimura K,Chugani DC,Muzik O,Chugani HT

更新日期：1999-03-10 00:00:00

abstract：:Extracranial and intracranial angioplasty and stenting of the cerebral vessels are being performed more frequently. One clinical trial demonstrated equivalent outcomes between extracranial carotid angioplasty and carotid endarterectomy, but the results in both groups were suboptimal. Concerns remain about the iatrogen...

journal_title：Neurology

authors： Chaturvedi S,Fessler R

更新日期：2002-09-10 00:00:00

abstract：OBJECTIVE:To describe the results of a multicenter study that validated two new patient-reported measures of neurologic impairment and disability for use in MS clinical research. BACKGROUND:Self-reported data can provide a cost-effective means to assess patient functioning, and can be useful for screening patients who...

journal_title：Neurology

authors： Schwartz CE,Vollmer T,Lee H

更新日期：1999-01-01 00:00:00

abstract：:We performed a multicenter prospective study on the incidence and prognosis of Guillain-Barré syndrome (GBS) in the Emilia-Romagna region (3,909,512 inhabitants), Italy, over a 2-year period (1992-1993). The case finding method was based on a surveillance system including neurologic departments, all private and public...

journal_title：Neurology

authors：

更新日期：1997-01-01 00:00:00

abstract：:From 536 patients with the CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasis), seven were identified as having peripheral neuropathy not attributable to another cause. Peripheral neuropathy developed 0 to 25 years after their first symptoms of scleroderma. Unex...

journal_title：Neurology

authors： Dyck PJ,Hunder GG,Dyck PJ

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:The objective of the present work is to examine images of the brain dissection by Flemish-born anatomist Andreas Vesalius (1514-1564) as originally represented in the Fabrica (1543), and later copied without Vesalius' permission by Spanish anatomist Juan Valverde de Hamusco (c1525-c1587) in Historia de la com...

journal_title：Neurology

authors： Lanska DJ,Lanska JR

更新日期：2013-02-26 00:00:00

abstract：:Twenty-nine untreated patients diagnosed with probable AD and 15 control patients underwent two or more clinical and volumetric MRI assessments with intervals ranging from 5 months to 6 years. The change in global cerebral volume for an individual was calculated by a novel method of registration and subtraction of ser...

journal_title：Neurology

authors： Fox NC,Scahill RI,Crum WR,Rossor MN

更新日期：1999-05-12 00:00:00

abstract：:We describe an atypical neurologic presentation of Wegener's granulomatosis (WG) with striking meningeal and cerebral involvement, responding to immunosuppressive therapy. WG may cause treatable intracranial complications in the absence of nasal or renal disease and without cerebral angiographic abnormalities, CSF ple...

journal_title：Neurology

authors： Weinberger LM,Cohen ML,Remler BF,Naheedy MH,Leigh RJ

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To discuss the indications and timing for resective surgery in patients with Sturge-Weber syndrome (SWS) and medication-resistant epilepsy. BACKGROUND:SWS that causes epilepsy severe enough to merit surgery is rare. Because of the variable natural history of the disease, it is difficult to establish clear-cu...

journal_title：Neurology

authors： Arzimanoglou AA,Andermann F,Aicardi J,Sainte-Rose C,Beaulieu MA,Villemure JG,Olivier A,Rasmussen T

更新日期：2000-11-28 00:00:00

abstract：OBJECTIVE:Current prehospital scales used to detect large vessel occlusion reveal very low endovascular thrombectomy (EVT) rates among selected patients. We developed a novel prehospital scale, the Madrid-Direct Referral to Endovascular Center (M-DIRECT), to identify EVT candidates for direct transfer to EVT-capable ce...

journal_title：Neurology

authors： Rodríguez-Pardo J,Riera-López N,Fuentes B,Alonso de Leciñana M,Secades-García S,Álvarez-Fraga J,Busca-Ostolaza P,Carneado-Ruiz J,Díaz-Guzmán J,Egido-Herrero J,Gil-Núñez A,Masjuan-Vallejo J,Real-Martínez V,Vivancos-Mora J,Díez

更新日期：2020-02-25 00:00:00