Reward acts on the pFC to enhance distractor resistance of working memory representations.

Abstract:

:Working memory and reward processing are often thought to be separate, unrelated processes. However, most daily activities involve integrating these two types of information, and the two processes rarely, if ever, occur in isolation. Here, we show that working memory and reward interact in a task-dependent manner and that this task-dependent interaction involves modulation of the pFC by the ventral striatum. Specifically, BOLD signal during gains relative to losses in the ventral striatum and pFC was associated not only with enhanced distractor resistance but also with impairment in the ability to update working memory representations. Furthermore, the effect of reward on working memory was accompanied by differential coupling between the ventral striatum and ignore-related regions in the pFC. Together, these data demonstrate that reward-related signals modulate the balance between cognitive stability and cognitive flexibility by altering functional coupling between the ventral striatum and the pFC.

journal_name

J Cogn Neurosci

authors

Fallon SJ,Cools R

doi

10.1162/jocn_a_00676

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

2812-26

issue

12

eissn

0898-929X

issn

1530-8898

journal_volume

26

pub_type

杂志文章
  • A role for cortical crosstalk in the binding problem: stimulus-driven correlations that link color, form, and motion.

    abstract::The putative independence of cortical mechanisms for color, form, and motion raises the binding problem-how is neural activity coordinated to create unified and correctly segmented percepts? Binding could be guided by stimulus-driven correlations between mechanisms, but the nature of these correlations is largely unex...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,评审

    doi:10.1162/0898929041502742

    authors: Billock VA,Tsou BH

    更新日期:2004-07-01 00:00:00

  • Dorsal striatal-midbrain connectivity in humans predicts how reinforcements are used to guide decisions.

    abstract::It has been suggested that the target areas of dopaminergic midbrain neurons, the dorsal (DS) and ventral striatum (VS), are differently involved in reinforcement learning especially as actor and critic. Whereas the critic learns to predict rewards, the actor maintains action values to guide future decisions. The diff...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21092

    authors: Kahnt T,Park SQ,Cohen MX,Beck A,Heinz A,Wrase J

    更新日期:2009-07-01 00:00:00

  • Perceptual fusion tendency of speech sounds.

    abstract::To discriminate and to recognize sound sources in a noisy, reverberant environment, listeners need to perceptually integrate the direct wave with the reflections of each sound source. It has been confirmed that perceptual fusion between direct and reflected waves of a speech sound helps listeners recognize this speech...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2010.21470

    authors: Huang Y,Li J,Zou X,Qu T,Wu X,Mao L,Wu Y,Li L

    更新日期:2011-04-01 00:00:00

  • Tracking the Emergence of Location-based Spatial Representations in Human Scene-Selective Cortex.

    abstract::Scene-selective regions of the human brain form allocentric representations of locations in our environment. These representations are independent of heading direction and allow us to know where we are regardless of our direction of travel. However, we know little about how these location-based representations are for...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01654

    authors: Berens SC,Joensen BH,Horner AJ

    更新日期:2020-12-07 00:00:00

  • The default network distinguishes construals of proximal versus distal events.

    abstract::Humans enjoy a singular capacity to imagine events that differ from the "here-and-now." Recent cognitive neuroscience research has linked such simulation processes to the brain's "default network." However, extant cognitive theories suggest that perceivers reliably simulate only relatively proximal experiences-those t...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00009

    authors: Tamir DI,Mitchell JP

    更新日期:2011-10-01 00:00:00

  • A cortical mechanism for triggering top-down facilitation in visual object recognition.

    abstract::The majority of the research related to visual recognition has so far focused on bottom-up analysis, where the input is processed in a cascade of cortical regions that analyze increasingly complex information. Gradually more studies emphasize the role of top-down facilitation in cortical analysis, but it remains somet...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,评审

    doi:10.1162/089892903321662976

    authors: Bar M

    更新日期:2003-05-15 00:00:00

  • fMRI activity patterns in human LOC carry information about object exemplars within category.

    abstract::Abstract The lateral occipital complex (LOC) is a set of areas in the human occipito-temporal cortex responding to objects as opposed to low-level control stimuli. Conventional functional magnetic resonance imaging (fMRI) analysis methods based on regional averages could not detect signals discriminative of different ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.20019

    authors: Eger E,Ashburner J,Haynes JD,Dolan RJ,Rees G

    更新日期:2008-02-01 00:00:00

  • Using Event-related Potentials to Inform the Neurocognitive Processes Underlying Knowledge Extension through Memory Integration.

    abstract::To build a general knowledge base, it is imperative that individuals acquire, integrate, and further extend knowledge across experiences. For instance, in one episode an individual may learn that George Washington was the first president. In a separate episode they may then learn that Washington was the commander of t...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01168

    authors: Varga NL,Bauer PJ

    更新日期:2017-11-01 00:00:00

  • Neurophysiological correlates of comprehending emotional meaning in context.

    abstract::Although the neurocognitive mechanisms of nonaffective language comprehension have been studied extensively, relatively less is known about how the emotional meaning of language is processed. In this study, electrophysiological responses to affectively positive, negative, and neutral words, presented within nonconstra...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.21151

    authors: Holt DJ,Lynn SK,Kuperberg GR

    更新日期:2009-11-01 00:00:00

  • The timing of action-monitoring processes in the anterior cingulate cortex.

    abstract::The anterior cingulate cortex (ACC) has been shown to respond to conflict between simultaneously active, incompatible response tendencies. This area is active during high-conflict correct trials and also when participants make errors. Here, we use the temporal resolution of high-density event-related potentials (ERPs)...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/08989290260045837

    authors: Van Veen V,Carter CS

    更新日期:2002-05-15 00:00:00

  • Hippocampal Context Processing during Acquisition of a Predictive Learning Task Is Associated with Renewal in Extinction Recall.

    abstract::Renewal is defined as the recovery of an extinguished response if extinction and retrieval contexts differ. The context dependency of extinction, as demonstrated by renewal, has important implications for extinction-based therapies. Persons showing renewal (REN) exhibit higher hippocampal activation during extinction ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00928

    authors: Lissek S,Glaubitz B,Schmidt-Wilcke T,Tegenthoff M

    更新日期:2016-05-01 00:00:00

  • Combining Multiple Functional Connectivity Methods to Improve Causal Inferences.

    abstract::Cognition and behavior emerge from brain network interactions, suggesting that causal interactions should be central to the study of brain function. Yet, approaches that characterize relationships among neural time series-functional connectivity (FC) methods-are dominated by methods that assess bivariate statistical a...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01580

    authors: Sanchez-Romero R,Cole MW

    更新日期:2021-02-01 00:00:00

  • Numerical values leave a semantic imprint on associated signs in monkeys.

    abstract::Animals and humans share an evolutionary ancient quantity representation which is characterized by analog magnitude features: Discriminating magnitudes becomes more difficult with increasing set sizes (size effect) and with decreasing distance between two numerosities (distance effect). Humans show these effects even ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21193

    authors: Diester I,Nieder A

    更新日期:2010-01-01 00:00:00

  • Moving mirrors: a high-density EEG study investigating the effect of camera movements on motor cortex activation during action observation.

    abstract::Action execution-perception links (mirror mechanism) have been repeatedly suggested to play crucial roles in social cognition. Remarkably, the designs of most studies exploring this topic so far excluded even the simplest traces of social interaction, such as a movement of the observer toward another individual. This ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00602

    authors: Heimann K,Umiltà MA,Guerra M,Gallese V

    更新日期:2014-09-01 00:00:00

  • Speech and span: working memory capacity impacts the use of animacy but not of world knowledge during spoken sentence comprehension.

    abstract::We present results from a study demonstrating that high- and low-span listeners show qualitatively different brain responses when comprehending simple active sentences. Participants listened to naturally produced sentences in three conditions in which the plausibility of thematic relations was manipulated, for instanc...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21400

    authors: Nakano H,Saron C,Swaab TY

    更新日期:2010-12-01 00:00:00

  • The White Matter Module-Hub Network of Semantics Revealed by Semantic Dementia.

    abstract::Cognitive neuroscience exploring the architecture of semantics has shown that coherent supramodal concepts are computed in the anterior temporal lobes (ATL), but it is unknown how/where modular information implemented by posterior cortices (word/object/face forms) is conveyed to the ATL hub. We investigated the semant...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01549

    authors: Sundqvist M,Routier A,Dubois B,Colliot O,Teichmann M

    更新日期:2020-07-01 00:00:00

  • Dynamic oscillatory processes governing cued orienting and allocation of auditory attention.

    abstract::In everyday listening situations, we need to constantly switch between alternative sound sources and engage attention according to cues that match our goals and expectations. The exact neuronal bases of these processes are poorly understood. We investigated oscillatory brain networks controlling auditory attention usi...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00452

    authors: Ahveninen J,Huang S,Belliveau JW,Chang WT,Hämäläinen M

    更新日期:2013-11-01 00:00:00

  • Who comes first? The role of the prefrontal and parietal cortex in cognitive control.

    abstract::Cognitive control processes enable us to adjust our behavior to changing environmental demands. Although neuropsychological studies suggest that the critical cortical region for cognitive control is the prefrontal cortex, neuro-imaging studies have emphasized the interplay of prefrontal and parietal cortices. This rai...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/0898929054985400

    authors: Brass M,Ullsperger M,Knoesche TR,von Cramon DY,Phillips NA

    更新日期:2005-09-01 00:00:00

  • Role of the right and left hemispheres in recovery of function during treatment of intention in aphasia.

    abstract::Two patients with residual nonfluent aphasia after ischemic stroke received an intention treatment that was designed to shift intention and language production mechanisms from the frontal lobe of the damaged left hemisphere to the right frontal lobe. Consistent with experimental hypotheses, the first patient showed im...

    journal_title:Journal of cognitive neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1162/0898929053279487

    authors: Crosson B,Moore AB,Gopinath K,White KD,Wierenga CE,Gaiefsky ME,Fabrizio KS,Peck KK,Soltysik D,Milsted C,Briggs RW,Conway TW,Gonzalez Rothi LJ

    更新日期:2005-03-01 00:00:00

  • Brain dynamics sustaining rapid rule extraction from speech.

    abstract::Language acquisition is a complex process that requires the synergic involvement of different cognitive functions, which include extracting and storing the words of the language and their embedded rules for progressive acquisition of grammatical information. As has been shown in other fields that study learning proces...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2011.21636

    authors: de Diego-Balaguer R,Fuentemilla L,Rodriguez-Fornells A

    更新日期:2011-10-01 00:00:00

  • Human frontal eye fields and spatial priming of pop-out.

    abstract::"Priming of pop-out" is a form of implicit memory that facilitates detection of a recently inspected search target. Repeated presentation of a target's features or its spatial position improves detection speed (feature/spatial priming). This study investigated a role for the human frontal eye fields (FEFs) in the prim...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2007.19.7.1140

    authors: O'Shea J,Muggleton NG,Cowey A,Walsh V

    更新日期:2007-07-01 00:00:00

  • Morphosyntactic processing in late second-language learners.

    abstract::The goal of the present study was to investigate the electrophysiological correlates of second-language (L2) morphosyntactic processing in highly proficient late learners of an L2 with long exposure to the L2 environment. ERPs were collected from 22 English-Spanish late learners while they read sentences in which morp...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21304

    authors: Dowens MG,Vergara M,Barber HA,Carreiras M

    更新日期:2010-08-01 00:00:00

  • Cortical representations sensitive to the number of perceived auditory objects emerge between 2 and 4 months of age: electrophysiological evidence.

    abstract::Sound waves emitted by two or more simultaneous sources reach the ear as one complex waveform. Auditory scene analysis involves parsing a complex waveform into separate perceptual representations of the sound sources [Bregman, A. S. Auditory scene analysis: The perceptual organization of sounds. London: MIT Press, 199...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00764

    authors: Folland NA,Butler BE,Payne JE,Trainor LJ

    更新日期:2015-05-01 00:00:00

  • The constraints functional neuroimaging places on classical models of auditory word processing.

    abstract::Several previous functional imaging experiments have demonstrated that auditory presentation of speech, relative to tones or scrambled speech, activate the superior temporal sulci (STS) bilaterally. In this study, we attempted to segregate the neural responses to phonological, lexical, and semantic input by contrastin...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/08989290152541421

    authors: Giraud AL,Price CJ

    更新日期:2001-08-15 00:00:00

  • In the eye of the beholder: individual differences in perceived social isolation predict regional brain activation to social stimuli.

    abstract::Prior research has shown that perceived social isolation (loneliness) motivates people to attend to and connect with others but to do so in a self-protective and paradoxically self-defeating fashion. Although recent research has shed light on the neural correlates of social perception, cooperation, empathy, rejection,...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21007

    authors: Cacioppo JT,Norris CJ,Decety J,Monteleone G,Nusbaum H

    更新日期:2009-01-01 00:00:00

  • The neural correlates of cognitive control: successful remembering and intentional forgetting.

    abstract::The ability to control how we process information by remembering that which is important and forgetting that which is irrelevant is essential to maintain accurate, up-to-date memories. As such, memory success is predicated on both successful intentional encoding and successful intentional forgetting. The current study...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00310

    authors: Rizio AA,Dennis NA

    更新日期:2013-02-01 00:00:00

  • Reward associations magnify memory-based biases on perception.

    abstract::Long-term spatial contextual memories are a rich source of predictions about the likely locations of relevant objects in the environment and should enable tuning of neural processing of unfolding events to optimize perception and action. Of particular importance is whether and how the reward outcome of past events can...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00314

    authors: Doallo S,Patai EZ,Nobre AC

    更新日期:2013-02-01 00:00:00

  • Electrophysiological evidence for reversed lexical repetition effects in language processing.

    abstract::Effects of word repetition are extremely robust, but can these effects be modulated by discourse context? We examined this in an ERP experiment that tested coreferential processing (when two expressions refer to the same person) with repeated names. ERPs were measured to repeated names and pronoun controls in two cond...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/089892904970744

    authors: Swaab TY,Camblin CC,Gordon PC

    更新日期:2004-06-01 00:00:00

  • Flexible information coding in human auditory cortex during perception, imagery, and STM of complex sounds.

    abstract::Auditory cortex is the first cortical region of the human brain to process sounds. However, it has recently been shown that its neurons also fire in the absence of direct sensory input, during memory maintenance and imagery. This has commonly been taken to reflect neural coding of the same acoustic information as duri...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00780

    authors: Linke AC,Cusack R

    更新日期:2015-07-01 00:00:00

  • Behavioral and electrophysiological evidence for early and automatic detection of phonological equivalence in variable speech inputs.

    abstract::Speech sounds are not always perceived in accordance with their acoustic-phonetic content. For example, an early and automatic process of perceptual repair, which ensures conformity of speech inputs to the listener's native language phonology, applies to individual input segments that do not exist in the native invent...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2011.21606

    authors: Kharlamov V,Campbell K,Kazanina N

    更新日期:2011-11-01 00:00:00