Thrombocytopenia associated with PF3 antiplatelet activity against the sulfa component of trimethoprim-sulfamethoxazole.

Abstract:

:A 3-year-old white boy had symptomatic thrombocytopenia after receiving trimethoprim-sulfamethoxazole in recommended doses for one week. The platelet count returned to normal soon after the medication was discontinued. In vitro admixing of donor platelets with a sample of the patient's serum demonstrated antiplatelet activity with the sulfamethoxazole component, but not with the trimethoprim component of the drug.

journal_name

South Med J

journal_title

Southern medical journal

authors

Schwartz RH,Rodriguez WJ,Luban NL

doi

10.1097/00007611-198105000-00039

subject

Has Abstract

pub_date

1981-05-01 00:00:00

pages

640-1

issue

5

eissn

0038-4348

issn

1541-8243

journal_volume

74

pub_type

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