Guillain-Barré syndrome as a paraneoplastic manifestation of small-cell carcinoma of lung.

Abstract:

:Guillain-Barré syndrome (GBS) encompasses the variants of acute immune-mediated polyneuropathies usually preceded by an infection. A few case reports have associated GBS to neoplastic diseases. It remains unclear whether these are merely coincidental or represent paraneoplastic phenomena. The clinical features of GBS associated with oncological cases do not appear to differ from post-infectious GBS. We report a 74-year-old man in whom small cell carcinoma of lung (SCLC) was diagnosed during a presentation with GBS. Treatment with chemotherapy for SCLC and intravenous immunoglobulins led to complete neurological recovery and tumor regression.

journal_name

South Med J

journal_title

Southern medical journal

authors

Naveed S,Okoli K,Hollingsworth J,Kasmani R

doi

10.1097/smj.0b013e3181bfd2c0

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

156-8

issue

2

eissn

0038-4348

issn

1541-8243

journal_volume

103

pub_type

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