Abstract:
:Autoimmune polyglandular syndrome (APS) is a disorder which is associated with multiple endocrine gland insufficiency and also with non-endocrine manifestations. The pathophysiology of APS is poorly understood, but the hallmark evidence of APS is development of autoantibodies against multiple endocrine and non-endocrine organs. These autoantibodies are responsible for the dysfunction of the affected organs and sometimes may also cause non-endocrine organ dysfunction. The hemolytic-uremic syndrome (HUS) is a serious and life-threatening disease which develops due to many etiological factors including autoimmune disorders. Here, we present an unusual case of APS. Ectodermal dysplasia with immune deficiency and HUS occurred concomitantly in the same patient with APS type 3c. Once the autoantibody generation was initiated in the human body, development of multiple disorders due to organ dysfunction and also autoantibody-related diseases may have occurred.
journal_name
J Clin Res Pediatr Endocrinoljournal_title
Journal of clinical research in pediatric endocrinologyauthors
Büyükçelik M,Keskin M,Keskin Ö,Bay A,Kılıç BD,Kor Y,Kılınç MA,Balat Adoi
10.4274/Jcrpe.1128subject
Has Abstractpub_date
2014-01-01 00:00:00pages
47-50issue
1eissn
1308-5727issn
1308-5735journal_volume
6pub_type
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journal_title:Journal of clinical research in pediatric endocrinology
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journal_title:Journal of clinical research in pediatric endocrinology
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更新日期:2019-05-28 00:00:00
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journal_title:Journal of clinical research in pediatric endocrinology
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doi:10.4274/jcrpe.v1i6.278
更新日期:2009-01-01 00:00:00
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journal_title:Journal of clinical research in pediatric endocrinology
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journal_title:Journal of clinical research in pediatric endocrinology
pub_type: 杂志文章
doi:10.4274/jcrpe.galenos.2019.2019.0080
更新日期:2020-03-19 00:00:00
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更新日期:2015-12-01 00:00:00
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更新日期:2013-01-01 00:00:00
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journal_title:Journal of clinical research in pediatric endocrinology
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journal_title:Journal of clinical research in pediatric endocrinology
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