Molecular analysis of an XY mare with gonadal dysgenesis.

Abstract:

:In this study, cytogenetic analysis of an infertile mare revealed a 64, XY karyotype. The XY sex-reversed animal had a female phenotype with gonadal dysgenesis. Using Southern blot analysis, we tested for the presence of two Y-specific genes SRY and ZFY by using DNA isolated from peripheral blood leukocytes. The results showed that at least the DNA-binding domain of the SRY gene was deleted from the Y chromosome of the XY mare but that the ZFY gene was present on this chromosome.

journal_name

Hereditas

journal_title

Hereditas

authors

Pailhoux E,Cribiu EP,Parma P,Cotinot C

doi

10.1111/j.1601-5223.1995.00109.x

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

109-12

issue

2

eissn

0018-0661

issn

1601-5223

journal_volume

122

pub_type

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