Karyotypic evolution in a human mucoepidermoid carcinoma.

Abstract:

:Chromosomes were studied in cultured material from two different areas of a human mucoepidermoid carcinoma. The detailed banding analyses showed no less than 41 different karyotypes. Comparisons between these revealed (1) that the tumour probably had originated with a normal, diploid stemline; (2) that the progression had mainly proceeded by steps in a hyperdiploid direction, by, as a rule, sequential numerical deviations; and (3) that there existed at least eight further, different, evolutionary products from the original stemline. The complex progressional pattern disclosed in the present case contrasts with cytogenetical data documented for most human benign as well as malignant tumour types.

journal_name

Hereditas

journal_title

Hereditas

authors

Mark J,Sandros J,Wedell B,Dahlenfors R,Stenman G

doi

10.1111/j.1601-5223.1989.tb00420.x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

75-8

issue

1

eissn

0018-0661

issn

1601-5223

journal_volume

110

pub_type

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