解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:The Aedes aegypti mosquito is a threat to human health across the globe. The A. aegypti genome was recently re-sequenced and re-assembled. Due to a combination of long-read PacBio and Hi-C sequencing, the AaegL5 assembly is chromosome complete and significantly improves the assembly in key areas such as the ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-021-00172-2
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:The molecular out of Africa hypothesis, OOAH, has been considered as an established fact amid population geneticists for some 25-30 years despite the early concern with it among phylogeneticists with experience beyond that of Homo. The palaeontological support for the hypothesis is also questionable, a circu...
journal_title:Hereditas
pub_type: 杂志文章,评审
doi:10.1186/s41065-020-00163-9
更新日期:2020-12-19 00:00:00
abstract:BACKGROUND:The Drosophila hindgut is commonly used model for studying various aspects of organogenesis like primordium establishment, further specification, patterning, and morphogenesis. During embryonic development of Drosophila, many transcriptional activators are involved in the formation of the hindgut. The transc...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-020-00160-y
更新日期:2020-11-19 00:00:00
abstract:BACKGROUND:The methylenetetrahydrofolate reductase (MTHFR) rs1801131 A/C variant results in a decrease in MTHFR enzymatic activity, which may play an important role in folate metabolism and is also an important source of DNA methylation and DNA synthesis. Several case-control studies have been conducted to assess the a...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-020-00129-x
更新日期:2020-04-27 00:00:00
abstract:BACKGROUND:Seven in absentia homolog 1 (SIAH1) is an E3 ubiquitin ligase containing a RING-finger domain and a key regulator of normal development. Skin and hair follicle development is a complex and special process of morphogenesis involving multiple signaling pathways. SIAH1 is enriched in the Wnt signaling pathway a...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-020-00126-0
更新日期:2020-04-06 00:00:00
abstract::Here, the pathogenesis of an IFIH1 gene mutation is discussed through the analysis of a sporadic case of hereditary spastic paraplegia. Next-generation sequencing was performed for the patient and his family members to detect mutations at the IFIH1 locus. The patient and his father were found to carry the same heteroz...
journal_title:Hereditas
pub_type: 杂志文章,评审
doi:10.1186/s41065-019-0104-x
更新日期:2019-08-13 00:00:00
abstract:Background:Rice planthoppers (main brown planthopper, Nilaparvata lugens Stål; BPH) was one of substantial threats to Asia rice production as its serious destruction and difficulties in control under field conditions. Notably, host-plant resistance was proved to be one of the effective ways to manage the pest. And stro...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-019-0098-4
更新日期:2019-06-26 00:00:00
abstract:Background:Cervical cancer is a malignancy that's common in female with high incidence and mortality worldwide. MicroRNAs (miRNAs) act a pivotal part in human cancer development. Our aim was to investigate the effect of miR-126 on cervical cancer and its underlying molecular mechanism. Results:Firstly, RT-qPCR assay r...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-019-0087-7
更新日期:2019-04-09 00:00:00
abstract:Background:Jerusalem artichoke (Helianthus tuberosus L.) is a characteristic crop in the Qinghai-Tibet Plateau which has rapidly developed and gained socioeconomic importance in recent years. Fructans are abundant in tubers and represent the foundation for their formation, processing and utilization of yield; and are a...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-019-0086-8
更新日期:2019-02-06 00:00:00
abstract:Background:Bladder cancer was a malignant disease in patients, our research aimed at discovering the possible biomarkers for the diseases. Results:The gene chip GSE31684, including 93samples, was downloaded from the GEO datasets and co-expression network was constructed by the data. Molecular complex detection(MCODE) ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-019-0083-y
更新日期:2019-01-28 00:00:00
abstract:Background:Recent large-scale genome-wide association studies (GWAS) have showed that the neuronal calcium signaling has pivotal roles in schizophrenia (SCZ) in populations of European of ancestry. However, it is not known if calcium signaling pathway genes are also associated with SCZ in Han Chinese population. Metho...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0054-0
更新日期:2018-01-02 00:00:00
abstract:Background:Genealogy and molecular genetic studies of a Swedish river valley population resulted in a large pedigree, showing that the hereditary hemochromatosis (HH) HFE/p.C282Y mutation is inherited with other recessive disorders such as Wilson´s disease (WND), a rare recessive disorder of copper overload. The popula...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0052-2
更新日期:2017-12-19 00:00:00
abstract:Background:Elymus sibiricus is an important native grass in Qinghai-Tibetan Plateau. Seed shattering is a serious problem for E. sibiricus, especially at harvest time. Cross breeding is an effective way to create new varieties with beneficial characteristic or improved traits, and to broaden genetic base. Results:In t...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0053-1
更新日期:2017-12-12 00:00:00
abstract:BACKGROUND:Chromosome microdissection is one of the most important techniques in molecular cytogenetic research. Cotton (Gossypium Linnaeus, 1753) is the main natural fiber crop in the world. The resistance gene analog (RGA) cloning after its single chromosome microdissection can greatly promote cotton genome research ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0035-3
更新日期:2017-05-18 00:00:00
abstract:BACKGROUND:Until recently, mechanisms of segmentation established for Drosophila served as a paradigm for arthropod segmentation. However, with the discovery of gene expression waves in vertebrate segmentation, another paradigm based on oscillations linked to axial growth was established. The Notch pathway and hairy de...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0029-1
更新日期:2017-04-27 00:00:00
abstract:BACKGROUND:While orchardgrass (Dactylis glomerata L.) is a well-known perennial forage species, rust diseases cause serious reductions in the yield and quality of orchardgrass; however, genetic mechanisms of rust resistance are not well understood in orchardgrass. RESULTS:In this study, a genome-wide association study...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-017-0027-3
更新日期:2017-02-23 00:00:00
abstract:BACKGROUND:Tomatoes provide a significant dietary source of the carotenoids, lycopene and β-carotene. During ripening, carotenoid accumulation determines the fruit colors while chlorophyll degradation. These traits have been, and continue to be, a significant focus for plant breeding efforts. Previous work has found st...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-016-0023-z
更新日期:2017-01-11 00:00:00
abstract:BACKGROUND:The Mount Huang eastern honey bees (Apis cerana) are an endemic population, which is well adapted to the local agricultural and ecological environment. In this study, the genetic structure of seven eastern honey bees (A. cerana) populations from Mount Huang in China were analyzed by SSR (simple sequence repe...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-016-0010-4
更新日期:2016-07-06 00:00:00
abstract:BACKGROUND:The common fig (Ficus carica L.) is a gynodioecious species with two sexual forms: male trees (caprifigs) with male and female flowers and female trees that produce only female flowers that will result in the edible fig syconium. In this study the genetic diversity of 20 Tunisian accessions of caprifig is an...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1186/s41065-015-0002-9
更新日期:2015-10-22 00:00:00
abstract::In 1921 Hereditas published an article on the fall of Rome written by the famous classical scholar Martin P:son Nilsson. Why was a paper on this unexpected topic printed in the newly founded journal? To Nilsson, the demise of the Roman Empire was explained by the "bastardization" occurring between "races" from differe...
journal_title:Hereditas
pub_type: 传,历史文章,杂志文章
doi:10.1111/hrd2.00080
更新日期:2014-12-01 00:00:00
abstract::A recombinant inbred line (RIL) population from a cross between 'HH1B' and 'RSB02' (a deep-water rice variety with resistance to sheath blight) was planted in two locations for four different growing seasons. Seven traits were used to evaluate the disease severity, namely disease rating (DR), lesion length (LL), lesio...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/hrd2.00026
更新日期:2014-06-01 00:00:00
abstract::Maize is the third important major food crop. Breeding for low phytate maize genotypes is an effective strategy for decreasing the content of kernel phytic acid (a chelator of cations such as Ca(2+) and Fe(3+) ) and thereby increasing the bioavailability of nutritive minerals in human diet and animal feed. Previous st...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2013.00030.x
更新日期:2014-02-01 00:00:00
abstract::In general, cyclins control the cell cycle. Not so the atypical cyclins, which are required for diverse cellular functions such as for genome stability or for the regulation of transcription and translation. The atypical Cyclin G (CycG) gene of Drosophila has been involved in the epigenetic regulation of abdominal seg...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2012.02273.x
更新日期:2012-10-01 00:00:00
abstract::To further understand the relationships between the SS genome of Sinapis arvensis and the AA, BB genomes in Brassica, genomic DNA of Sinapis arvensis was hybridized to the metaphase chromosomes of Brassica nigra (BB genome), and the metaphase chromosomes and interphase nucleus of Brassica rapa (AA genome) by comparati...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2012.02248.x
更新日期:2012-06-01 00:00:00
abstract::The highly invasive Chinese mitten crabs (Eriocheir sinensis) was studied to reveal the genetic relationship between three none self-sustainable population within the Polish Oder and Vistula River and Lake Vänern in Sweden. Crabs from self-sustainable populations were collected from the Elbe River (Germany), San Franc...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2012.02246.x
更新日期:2012-04-01 00:00:00
abstract::Two x-type high molecular weight glutenin subunits (HMW-GS) in Aegilops tauschii, 1Dx3(t) and 1Dx4(t) were identified by SDS-PAGE and MALDI-TOF-MS. Their complete coding sequences were isolated by AS-PCR. 1Dx3(t) and 1Dx4(t) genes consist of 2535 bp and 2508 bp and encode 845 and 836 amino acid residues, respectively....
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2011.02215.x
更新日期:2012-02-01 00:00:00
abstract::The association between recombination rate and diversity, but not divergence is considered to be driven mainly by natural selection: fixation of positively selected variants and associated hitchhiking effects and/or background selection eliminating deleterious alleles. In the present study, we investigated the relatio...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2010.02210.x
更新日期:2011-04-01 00:00:00
abstract::Anhidrotic ectodermal dysplasia (EDA) is a genetic disease characterized by the absence or hypoplasia of hair, teeth and eccrine sweat glands that has been reported in humans, the tabby mouse mutants, cattle and dogs. The EDA gene on the X chromosome encodes a protein, ectodysplasin-A (EDA), which is responsible for E...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2010.02202.x
更新日期:2011-02-01 00:00:00
abstract::Partial amphiploids between wheat (Triticum aestivum L.) and Thinopyrum species play an important role in the transfer and use of traits from alien species. A wheat-Thinopyrum intermedium partial amphiploid, TAI8335, and its alien parent were characterized by a combination of genomic in situ hybridization (GISH) and c...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2010.02156.x
更新日期:2010-12-01 00:00:00
abstract::The mammalian protein kinase D family is involved in manifold cellular processes including cell migration and motility. Recently it was shown that human PKD1 and PKD2 phosphorylate and thereby inhibit Slingshot 1 Like (SSH1L), a phosphatase which is central to the regulation of actin cytoskeletal dynamics. We noted be...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2010.02200.x
更新日期:2010-10-01 00:00:00
abstract::Low polymorphism in cultivated watermelon has been reported in previous studies, based mainly on US Plant Introductions and watermelon cultivars, most of which were linked to breeding programmes associated with disease resistance. Since germplasm sampled in a putative centre of origin in southern Africa may harbour co...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2010.02165.x
更新日期:2010-08-01 00:00:00
abstract::Ur1 enhances secondary rachis-branching, resulting in more spikelets per panicle. This genic effect can increase grain yield by enlarging sink size. We conducted mapping of Ur1 using SSR markers, and detected markers usable for the MAS (marker-assisted selection) for Ur1. Three Ur1 isogenic lines of recurrent parents ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2009.02108.x
更新日期:2009-12-01 00:00:00
abstract::Chromosomal rearrangements have played a key role in the speciation of the New World sexual Artemia species (Crustacea, Anostraca) A. franciscana and A. persimilis. The species differ by a chromosome duplication (2n+2=44 in A. persimilis vs 2n=42 in A. franciscana), and a greater amount of heterochromatin (HCH) in A. ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2009.02109.x
更新日期:2009-05-01 00:00:00
abstract::It has been reported that oxidative stress is a factor in cerebral infarction (CI). Extracellular superoxide dismutase (EC-SOD) is important in preventing oxidative stress, and the cerebral infarct size of EC-SOD knockout mice is significantly larger than that in wild-type controls. The aim of this study was to invest...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2008.02086.x
更新日期:2008-12-01 00:00:00
abstract::Selection on endosperm traits among individual kernels is very important in maize because the characteristics of the kernel, especially the endosperm, are directly related to quality and yield. However the accuracy of the selection according to endosperm phenotype may be affected by heterofertilization. The objective ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.1601-5223.2008.02056.x
更新日期:2008-10-01 00:00:00
abstract::Trees of 68 apple cultivars, aimed for preservation by the 'National Program for diversity of cultivated plants' as mandate cultivars, were analysed using a set of 10 SSR (simple sequence repeat) primer pairs and the self-incompatibility (S-)locus to evaluate genetic diversity and reveal inter-cultivar relationships. ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.0018-0661.2008.02042.x
更新日期:2008-06-01 00:00:00
abstract::Within and among populations genetic variance of twelve Hemarthria compressa populations and one Hemarthria japonica population from China were analyzed using inter simple sequence repeat (ISSR). Twelve primers amplified a total of 165 genomic DNA fragments across a total of 148 individuals of which 156 were polymorph...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.0018-0661.2008.02031.x
更新日期:2008-04-01 00:00:00
abstract::Heredity can be followed in persons or in genes. Persons can be identified only a few generations back, but simplified models indicate that universal ancestors to all now living persons have occurred in the past. Genetic variability can be characterized as variants of DNA sequences. Data are available only from living...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.0018-0661.2008.2041.x
更新日期:2008-02-01 00:00:00
abstract::The northern Swedish population has a history of admixture of three ethnic groups and a dramatic population growth from a relatively small founder population. This has resulted in founder effects that together with unique resources for genealogical analyses provide excellent conditions for genetic mapping of monogenic...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.2007.0018-0661.02007.x
更新日期:2007-11-01 00:00:00
abstract::Seventeen Danish accessions of five taxa of Barbarea, i.e. B. stricta, B. verna, B. intermedia and B. vulgaris ssp. vulgaris and ssp. arcuata including the two morphologically and biochemically differentiated P(pubescent)- and G(glabrous)-types, and 4 P-xG-type hybrids were analysed cytologically using fluorescent in ...
journal_title:Hereditas
pub_type: 杂志文章
doi:10.1111/j.2007.0018-0661.01987.x
更新日期:2007-09-01 00:00:00