Abstract:
:Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this study was to investigate the effectiveness of MT in prognostic improvement. We retrospectively analyzed 72 patients with CLI and assessed whether MT improved prognosis. The incidence of amputation-free survival (freedom from major amputation [MA] and death) was significantly different between the MT and conventional groups at 2 years (0% vs 33%; P = .024). After multivariate analysis, transfusion (hazard ratio [HR] 5.778; 95% confidence interval [CI], 2.372-14.073; P < .001), multivessel coronary disease (HR 3.353; 95% CI, 1.309-8.590; P = .012), and C-reactive protein >5 mg/dL (HR 3.958; 95% CI, 1.359-11.531; P = .012) were independent predictors for MA or death. We concluded that MT was effective in improved mortality and limb salvage rate.
journal_name
Angiologyjournal_title
Angiologyauthors
Hioki H,Miyashita Y,Miura T,Ebisawa S,Motoki H,Izawa A,Tomita T,Koyama J,Ikeda Udoi
10.1177/0003319714523113subject
Has Abstractpub_date
2015-02-01 00:00:00pages
187-94issue
2eissn
0003-3197issn
1940-1574pii
0003319714523113journal_volume
66pub_type
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