Prognostic improvement by multidisciplinary therapy in patients with critical limb ischemia.


:Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this study was to investigate the effectiveness of MT in prognostic improvement. We retrospectively analyzed 72 patients with CLI and assessed whether MT improved prognosis. The incidence of amputation-free survival (freedom from major amputation [MA] and death) was significantly different between the MT and conventional groups at 2 years (0% vs 33%; P = .024). After multivariate analysis, transfusion (hazard ratio [HR] 5.778; 95% confidence interval [CI], 2.372-14.073; P < .001), multivessel coronary disease (HR 3.353; 95% CI, 1.309-8.590; P = .012), and C-reactive protein >5 mg/dL (HR 3.958; 95% CI, 1.359-11.531; P = .012) were independent predictors for MA or death. We concluded that MT was effective in improved mortality and limb salvage rate.






Hioki H,Miyashita Y,Miura T,Ebisawa S,Motoki H,Izawa A,Tomita T,Koyama J,Ikeda U




Has Abstract


2015-02-01 00:00:00














  • Graphic findings in acute aortic regurgitation caused by destruction of aortic cusp. The origin of first heart sound.

    abstract::The diagnosis of ruptured aortic cusp leading to acute aortic insufficiency was made by echophonocardiographic techniques in a patient with nonvegetative aortic valvular endocarditis and a negative clinical history. Early closure of the mitral valve, weak first heart sound, tall A wave of apexcardiogram, and early dia...


    pub_type: 杂志文章


    authors: Zoneraich S,Zoneraich O,Rhee JJ,Gupta MP

    更新日期:1977-01-01 00:00:00

  • Sinus node suppression in acute strokes--case reports.

    abstract::The authors report on 5 patients, 4 of them observed over a period of only two months in one community hospital, who developed profound sinus node suppression in the early phase following acute strokes. This complication resulted in the death of 2; in the remaining 3, it was controlled by electrical cardiac pacing or ...


    pub_type: 杂志文章


    authors: Bashour TT,Cohen MS,Ryan C,Antonini C Sr

    更新日期:1988-12-01 00:00:00

  • Right coronary arteriocameral fistula into the right ventricle. An inspiratory accentuation of continuous murmur: a case report.

    abstract::A case of a right coronary artery fistula into the right ventricle is presented. The clinical diagnosis was based on the presence of a continuous murmur best heard in the epigastrium, which increased in intensity and duration on inspiration . This report stresses the importance of this sign in the localization of the ...


    pub_type: 杂志文章


    authors: Munsi SC,Dalal JJ,Nair KG

    更新日期:1979-03-01 00:00:00

  • Venous plethysmography applied in pathologic conditions.

    abstract::The correlation between venography and SGP in 41 patients was studied. Fourteen normal subjects were used as a reference. SGP was shown to be very sensitive (97.5%), including proximal and distal DVT, and highly specific (96.4%). After some recommendations for patient positioning and technical use, it will enhance bot...


    pub_type: 杂志文章


    authors: Baccalon H,Chikhany G,Lozes A,Vaislic C,Puel P,Enjalbert A

    更新日期:1981-12-01 00:00:00

  • Prognostic Factors and Outcomes in Young Patients With Presented of Different Types Acute Coronary Syndrome.

    abstract::The prevalence of coronary artery disease is increasing in young adults. We evaluated the outcomes of different types of acute coronary syndrome in 917 patients undergoing coronary angiography aged ≤45 years. Male sex, smoking, dyslipidemia were the most important risk factors. ST-elevation myocardial infarction (STEM...


    pub_type: 杂志文章


    authors: Yılmaz S,Coşansu K

    更新日期:2020-11-01 00:00:00

  • Finger systolic pressures and skin temperatures in severe Raynaud's syndrome: the relationship to healing of skin lesions and the use of oral phenoxybenzamine.

    abstract::Systolic pressures and skin temperatures were studied in 23 patients with severe Raynaud's syndrome who were given oral phenoxybenzamine. There was a relationship between the measurements and the severity of the disease. Statistically significant correlation was found between the measurements and the time for healing ...


    pub_type: 杂志文章


    authors: Carter SA

    更新日期:1981-05-01 00:00:00

  • Physical activity and cardiovascular disease prevention: current recommendations.

    abstract::Epidemiologic studies support an inverse and robust relationship between physical activity (PA) and mortality risk, even after adjusting for potential confounding factors. The authors have reported 13% lower mortality risk for every 1-MET (metabolic equivalent) increase in exercise capacity. For those with an exercise...


    pub_type: 杂志文章,评审


    authors: Kokkinos P

    更新日期:2008-04-01 00:00:00

  • Pulmonary tuberculosis with multiple saccular aneurysms of the aorta--a case report.

    abstract::A forty-eight-year-old man presented with cavitary pulmonary tuberculosis and widening of the mediastinum. Mediastinal widening was due to multiple saccular aneurysms of the ascending aorta and the arch of the aorta. The various presentations of tubercular aortitis and the reasons for considering alternative etiology ...


    pub_type: 杂志文章


    authors: Mally A,D'Souza C,Dwivedi S,Shatapathi P

    更新日期:1990-04-01 00:00:00

  • Acute diastolic dysfunction due to pneumomediastinum following positive end-expiratory pressure--a case report.

    abstract::A 78-year-old woman was admitted for pulmonary embolism requiring orotracheal intubation and positive end-expiratory pressure. The pulmonary angiography confirmed a massive pulmonary embolism as suggested by echocardiography. Heparin and recombinant tissue plasminogen activator were successfully administrated; neverth...


    pub_type: 杂志文章


    authors: Rigatelli G,Zanchetta M,Pedon L,Zennaro M,Maiolino P

    更新日期:2004-07-01 00:00:00

  • Ranolazine enhances the antiarrhythmic activity of amiodarone by accelerating conversion of new-onset atrial fibrillation after cardiac surgery.

    abstract::Ranolazine is a relatively novel antiischemic/antianginal compound with antiarrhythmic properties. We investigated its ability to shorten the time to conversion of postoperative atrial fibrillation (POAF) when added to amiodarone after coronary artery bypass graft (CABG) surgery. In this prospective, randomized, alloc...


    pub_type: 杂志文章,随机对照试验


    authors: Simopoulos V,Tagarakis GI,Daskalopoulou SS,Daskalopoulos ME,Lenos A,Chryssagis K,Skoularingis I,Molyvdas PA,Tsilimingas NB,Aidonidis I

    更新日期:2014-04-01 00:00:00

  • Dietary treatment of lymphedema by restriction of long-chain triglycerides.

    abstract::Two patients suffering from idiopathic unilateral lower limb lymphedema were treated with a diet in which long-chain triglycerides (LCT) were drastically restricted. From the beginning of the treatment, a distinct improvement was observed in both patients, with reduction of the affected limb perimeters, decrease of ed...


    pub_type: 杂志文章


    authors: Soria P,Cuesta A,Romero H,Martínez FJ,Sastre A

    更新日期:1994-08-01 00:00:00

  • Atherosclerosis vascular damage in elderly athletes and sedentary people.

    abstract::The objective of this study was to determine the degree of vascular atherosclerotic damage at the carotid and femoral levels in a group of subjects over sixty years old practicing endurance sports. Using high-resolution Doppler-color flow ultrasonography the authors carried out a vascular screening, comparing two dist...


    pub_type: 杂志文章


    authors: Galetta F,Rossi M,Franzoni F,Credidio L,Vagheggini G

    更新日期:1997-07-01 00:00:00

  • Do vasospasms provoke ocular diseases?

    abstract::Vasospasms in the eye are often combined with digital vasospasms, as can be diagnosed with a nailfold capillaroscopic local cooling test. In 16 patients with a history of cold hands and feet the presence of peripheral vasospasms without any underlying disease was demonstrated by means of nailfold video-capillaroscopy....


    pub_type: 杂志文章


    authors: Gasser P,Flammer J,Guthauser U,Mahler F

    更新日期:1990-03-01 00:00:00

  • A non-invasive index of leg arterial perfusion pressure during walking, derived from cutaneous toe temperature.

    abstract::This article describes and evaluates a non-invasive technique for continuous monitoring of hemodynamic changes in the legs during walking. The method involves monitoring of cutaneous toe temperature. In six normal subjects we have shown that, during exercise under carefully controlled conditions, a unique steady-state...


    pub_type: 杂志文章


    authors: Baccelli G,Corbellini E,Walsh JT,Busca S,Boccaccini U,Zanchetti A

    更新日期:1985-08-01 00:00:00

  • Lymphangiomyomatosis--newer concepts in pathogenesis and management--case reports.

    abstract::Lymphangiomyomatosis was first reported more than forty years ago. Although its incidence is rare, its occurrence is being increasingly recognized and has been the subject of a growing number of cases reports in recent years. This study adds 2 more cases to the file. Both cases involved young women with the characteri...


    pub_type: 杂志文章


    authors: Naegeli CD,Cordasco EM,Meden G,O'Donnell JK,MacIntyre WJ,Dishner W

    更新日期:1990-11-01 00:00:00

  • Accelerated wound healing: multidisciplinary advances in the care of venous leg ulcers.

    abstract::The etiologies of venous leg ulcers have been well known for millennia, and yet there remains no simple solution to this very common problem. Achieving closure of venous leg ulcers is often a lengthy process that is further complicated by the presence of significant comorbidities. The authors present data on healing v...


    pub_type: 杂志文章


    authors: Bongiovanni CM,Hughes MD,Bomengen RW

    更新日期:2006-03-01 00:00:00

  • Outcomes in Patients Fully Covered With Coronary Artery Aneurysm and Stenosis Lesion by Second Generation Drug-Eluting Stents After 1 Year.

    abstract::We evaluated the safety and efficacy of second-generation drug-eluting stents (DES) fully covering a coronary artery aneurysm (CAA) and stenosis lesion. Patients (n = 33) with CAA and stenosis lesion (>60%) were enrolled between January 2014 and December 2017. Baseline characteristics and biochemical variables were re...


    pub_type: 杂志文章


    authors: Wu Z,Xu C,You W,Ye F,Wu X

    更新日期:2020-11-01 00:00:00

  • Pulmonary edema of environmental origin--newer concepts.

    abstract::Pulmonary edema of non-cardiac origin is usually an urgent clinical problem, which has recently increased in frequency throughout the world in the past few years. This is partly due to sociological factors and to pre-eminent advances in industrial technology. Recent severe massive toxic gas explosions have had nationa...


    pub_type: 杂志文章


    authors: Cordasco EM,Demeter SR,Kester L,Cordasco MA,Lammert G,Beerel F

    更新日期:1986-06-01 00:00:00

  • Collaterals that regressed after angioplasty can be recruited to protect the left ventricle in case of an acute occlusion.

    abstract::A considerable fraction of collaterals has been shown to regress immediately after percutaneous transluminal coronary angioplasty (PTCA), but the fate of these well-developed collaterals is unknown. The authors aimed to show the protective role of these recruitable collaterals in case of an acute myocardial infarction...


    pub_type: 杂志文章


    authors: Ozdemir O,Soylu M,Demir AD,Alyan O,Topaloglu S,Geyik B,Kütük E

    更新日期:2005-09-01 00:00:00

  • A young girl with vasospastic angina associated with mutation in endothelial nitric oxide synthase gene--a case report.

    abstract::A 13-year-old girl was successfully recuperated from cardiopulmonary arrest shortly after running 80 m in a competition. The electrocardiogram, echocardiogram and 123I-MIBG myocardial scintigraphic imaging indicated myocardial ischemia in the anteroseptal wall of the left ventricle. Coronary angiography during the rec...


    pub_type: 杂志文章


    authors: Fukuda N,Kurokawa S,Maeda K,Iseki S,Takahasi M,Niwano H,Nakazato K,Niwano S,Kurosawa T,Izumi T

    更新日期:2003-03-01 00:00:00

  • Association of remodeling with endothelial shear stress, plaque elasticity, and volume in coronary arteries: a pilot coronary computed tomography angiography study.

    abstract::We sought to noninvasively assess the relationship between arterial remodeling, endothelial shear stress (ESS), and wall stiffness in coronary arteries. We studied 28 coronary arteries from 22 patients undergoing coronary computed tomography angiography (CCTA). The ESS was calculated in 2-mm long segments using comput...


    pub_type: 杂志文章


    authors: Katranas SA,Kelekis AL,Antoniadis AP,Chatzizisis YS,Giannoglou GD

    更新日期:2014-05-01 00:00:00

  • Clinical efficacy of micronized purified flavonoid fraction (MPFF) in edema.

    abstract::Swelling is one of the most frequent complaints of patients in daily clinical practice; leg edema is its objective confirmation. It can be associated with several diseases. Micronized purified flavonoid fraction (MPFF) is a phlebotropic drug commonly used to treat the signs and symptoms associated with chronic venous ...


    pub_type: 杂志文章


    authors: Olszewski W

    更新日期:2000-01-01 00:00:00

  • Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel on transcutaneous PO2 in venous insufficiency.

    abstract::A gel including aescin, essential phospholipids (EPL), and heparin (EG) has been used for many years for local treatment of venous, microcirculatory alterations (varicose veins, chronic venous insufficiency). Bruises, swelling, thrombophlebitis, and contusions are effectively treated with this compound. The aim of thi...


    pub_type: 杂志文章


    authors: Cesarone MR,Belcaro G,Ippolito E,Ricci A,Ruffini M,Dugall M

    更新日期:2004-05-01 00:00:00

  • Duplex ultrasound scanning (DUS) versus computed tomography angiography (CTA) in the follow-up after EVAR.

    abstract:INTRODUCTION:Computed tomography angiography (CTA) is the gold standard follow-up modality after endovascular aneurysm repair (EVAR). A potential alternative noninvasive and less expensive modality is duplex ultrasound scanning (DUS). METHODS:We studied 314 follow-up paired scans (DUS and CTA) in 59 patients with EVAR...


    pub_type: 杂志文章


    authors: Badri H,El Haddad M,Ashour H,Nice C,Timmons G,Bhattacharya V

    更新日期:2010-02-01 00:00:00

  • Heparin and prostacyclin.

    abstract::Hemodialysis performed with prostacyclin (5 ng/kg/min) as a substitute for heparin was studied in 10 patients. The subjects were studied during heparin perfusion alone and during heparin perfusion together with prostacyclin. The authors investigated the effect of two heparin regimens (regimen I: 2,000 U/hr and regimen...


    pub_type: 杂志文章


    authors: Camici M,Evangelisti L

    更新日期:1989-04-01 00:00:00

  • Anomalous chordae tendinae. A source of echocardiographic confusion.

    abstract::A unique instance of an anomalous chorda tendinae visualized in the left ventricular outflow tract during M-Mode and two-dimensional echocardiography, and subsequently confirmed during surgery for concomitant severe rheumatic valvular disease, is described. The M-Mode appearance can be confused with more serious forms...


    pub_type: 杂志文章


    authors: Choo MH,Chia BL,Wu DC,Tan AT,Ee BK

    更新日期:1982-11-01 00:00:00

  • Classification of Aortic Stenosis by Flow and Gradient Patterns Provides Insights into the Pathophysiology of Disease.

    abstract::Different patterns of flow and valve gradients can lead to diagnostic uncertainty about the severity of aortic stenosis (AS). Consecutive patients with severe AS (valve area <1 cm(2)) underwent echocardiography and computed tomography. Patients were classified into 4 groups (high-gradient/normal flow [HGNF], high-grad...


    pub_type: 杂志文章


    authors: Bhattacharyya S,Mittal T,Abayalingam M,Kabir T,Dalby M,Cleland JG,Baltabaeva A,Rahman Haley S

    更新日期:2016-08-01 00:00:00

  • Primary stenting of the superior mesenteric artery for treatment of chronic mesenteric ischemia--a case report.

    abstract::Percutaneous transluminal angioplasty (PTA) has been well described in the treatment of mesenteric artery stenoses but has met with limited success in ostial lesions. The authors describe a case of a 79-year-old woman diagnosed with chronic mesenteric ischemia associated with a 22-pound weight loss and postprandial pa...


    pub_type: 杂志文章


    authors: Forauer AR,McLean GK

    更新日期:1999-01-01 00:00:00

  • Effect of long-term administration of buflomedil on regional cerebral blood flow in chronic cerebral infarction.

    abstract::The influence of long-term oral administration of buflomedil on regional cerebral blood flow was investigated in 10 patients with chronic cerebral infarction and mild to moderate mental deterioration. Patients were given 150 mg buflomedil three times daily for a period of eight weeks. Regional cerebral blood flow (rCB...


    pub_type: 杂志文章


    authors: Kobayashi S,Yamaguchi S,Okada K,Kitani M,Yamashita K,Shimote K,Tsunematsu T

    更新日期:1988-11-01 00:00:00

  • Errors of computer electrocardiography.

    abstract::A review of 6938 computer-generated electrocardiogram interpretations was undertaken by a single cardiologist. The computer-assisted program correctly interpreted 51.6% of the tracings. One or more corrections were necessary in 48.4%. The greatest number of incorrect interpretations involved repolarization (T wave) ab...


    pub_type: 杂志文章


    authors: RuDusky BM

    更新日期:1997-12-01 00:00:00