ERP indices of auditory selective attention in aging and Parkinson's disease.


:In the present study, we compared the performance of normal subjects in three age groups and of medicated Parkinson's disease patients on auditory selective attention processes. Two tone sequences were dichotically presented. Subjects responded to deviant tones in the attended location. Event-related potentials (ERPs) were recorded from nine scalp electrodes. The old group showed significant decline in hit rate, increase in N1 amplitude, and reduction in P3a, P3b, target negativity, and mismatch negativity amplitude. The amplitude and duration of late Nd increased with age, reflecting modulation of both attended and unattended standard ERPs. Although the middle group showed a similar pattern of ERP changes, the effects were generally nonsignificant. The Parkinson's disease group showed little further disruption of behavioral or ERP measures. However, Parkinson's disease affected late Nd in the direction opposite of that of aging, reflecting differential modulation of unattended standard positivity.






Karayanidis F,Andrews S,Ward PB,Michie PT




Has Abstract


1995-07-01 00:00:00












  • Autonomic cardiac control. III. Psychological stress and cardiac response in autonomic space as revealed by pharmacological blockades.

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Berntson GG,Cacioppo JT,Binkley PF,Uchino BN,Quigley KS,Fieldstone A

    更新日期:1994-11-01 00:00:00

  • The effects of an acute psychological stressor on cardiovascular, endocrine, and cellular immune response: a prospective study of individuals high and low in heart rate reactivity.

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    pub_type: 杂志文章


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    更新日期:1994-05-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 临床试验,杂志文章,随机对照试验


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    更新日期:2002-11-01 00:00:00

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    pub_type: 杂志文章


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