Abstract：
:Anatomically, diaphragmatic agenesis (DA) is the most extreme form of congenital diaphragmatic defect, but clinically it has not been defined separately from Bochdalek's hernia (BH). Between 1986 and 1992, the authors treated 55 neonates who had diaphragmatic defects. Forty-eight of these cases presented within 24 hours of birth. Seventeen of these neonates (35.4%) were found to have DA; the other 31 (64.6%) had BH. There were no significant differences in maternal age, gestational age, gender ratio, birth weight, and incidence of coexisting congenital anomalies between the two groups. However, neonates with DA differed significantly from those with BH with respect to incidence of antenatal diagnosis (76.4% v 12.5%, P = .0004), mean Apgar scores at 1 (4.1 +/- 2.0 v 5.7 +/- 2.3; P = .034) and 5 (5.5 +/- 2.7 v 7.6 +/- 2.2; P = .016) minutes, mean duration of preoperative stabilization (2.8 +/- 2.0 v 2.1 +/- 1.9 days; P = .044), and postoperative respiratory support (27.7 +/- 13.6 v 9.3 +/- 8.0 days; P = .002). Complications occurred in all seven DA survivors (100%) and in only four (19.0%) of the 21 BH survivors (P = .0008). The long-term survival rate was significantly lower for neonates with DA (29.4% v 64.5%; P = .04). Diaphragmatic agenesis is a distinct clinical entity; its unique short- and long-term problems require careful management.
journal_name
J Pediatr Surgjournal_title
Journal of pediatric surgeryauthors
Tsang TM,Tam PK,Dudley NE,Stevens Jdoi
10.1016/0022-3468(95)90599-5subject
Has Abstractpub_date
1995-01-01 00:00:00pages
16-8issue
1eissn
0022-3468issn
1531-5037pii
0022-3468(95)90599-5journal_volume
30pub_type
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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doi：10.1016/0022-3468(95)90329-1
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doi：10.1016/j.jpedsurg.2020.06.025
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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doi：10.1016/j.jpedsurg.2014.05.017
更新日期：2014-10-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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更新日期：1998-02-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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doi：10.1016/j.jpedsurg.2008.06.011
更新日期：2009-03-01 00:00:00
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journal_title：Journal of pediatric surgery
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doi：10.1016/s0022-3468(80)80133-3
更新日期：1980-06-01 00:00:00
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journal_title：Journal of pediatric surgery
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doi：10.1016/s0022-3468(98)90465-1
更新日期：1998-02-01 00:00:00
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doi：10.1016/s0022-3468(99)90765-0
更新日期：1999-06-01 00:00:00
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更新日期：1986-07-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2004.02.008
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journal_title：Journal of pediatric surgery
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doi：10.1016/s0022-3468(97)90640-0
更新日期：1997-06-01 00:00:00
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journal_title：Journal of pediatric surgery
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更新日期：2003-03-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2015-10-01 00:00:00
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journal_title：Journal of pediatric surgery
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doi：10.1016/j.jpedsurg.2012.10.024
更新日期：2013-01-01 00:00:00
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更新日期：2009-11-01 00:00:00
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journal_title：Journal of pediatric surgery
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