Abstract:
:The prevalence of iron deficiency was determined in Göteborg, Sweden, in a sample of 15- to 16-y-old girls (n = 220) and boys (n = 207) using serum ferritin (SF). In a recent study in women on the relationship between SF and stainable bone marrow iron, it was established that at a cutoff value for SF of < 16 micrograms/L in 75% of women with no iron stores SF concentration was below this value (sensitivity 75%), whereas in 98% of iron-replete women it was above this cutoff value (specificity 98%). The present study showed that in 40% of the girls and 15% of the boys SF was below this cutoff value, indicating iron deficiency. Low SF concentration was associated with significant decreases in transferrin saturation, Hb concentration, mean corpuscular Hb, and mean corpuscular volume. The results from this cross-sectional study showed that, with decreasing SF, the decrease of values for these parameters occurred already before SF had reached the level 16 micrograms/L, suggesting that SF can be validly used as a single criterion of iron deficiency. Using the cutoff value SF < 16 micrograms/L, the figures for the prevalence of iron deficiency in adolescents in different countries were compared and found to be rather similar in Australia, Canada, the United States, and Sweden. High iron requirements combined with the present low-energy life-style leading to an insufficient supply of dietary iron may be a reasonable main explanation for the paradoxical, high prevalence of iron deficiency in adolescents in affluent societies.
journal_name
Pediatr Resjournal_title
Pediatric researchauthors
Hallberg L,Hultén L,Lindstedt G,Lundberg PA,Mark A,Purens J,Svanberg B,Swolin Bdoi
10.1203/00006450-199311000-00023subject
Has Abstractpub_date
1993-11-01 00:00:00pages
680-7issue
5eissn
0031-3998issn
1530-0447journal_volume
34pub_type
杂志文章abstract::Guinea pig gallbladder smooth muscle contractility undergoes a period of postnatal maturation. Because tissues from adult animals contract more forcefully than tissues from newborn animals when stimulated with agonists that activate the contractile process through different mechanisms (receptor activation, membrane de...
journal_title:Pediatric research
pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
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更新日期:1990-12-01 00:00:00
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更新日期:2001-02-01 00:00:00
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更新日期:2005-09-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198501000-00006
更新日期:1985-01-01 00:00:00
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journal_title:Pediatric research
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更新日期:1993-06-01 00:00:00
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更新日期:2019-09-01 00:00:00
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doi:10.1203/00006450-199506000-00014
更新日期:1995-06-01 00:00:00
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更新日期:2006-07-01 00:00:00
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journal_title:Pediatric research
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doi:10.1203/00006450-199302000-00018
更新日期:1993-02-01 00:00:00
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pub_type: 临床试验,杂志文章
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doi:10.1203/00006450-199102000-00021
更新日期:1991-02-01 00:00:00
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更新日期:1997-07-01 00:00:00
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journal_title:Pediatric research
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更新日期:1999-07-01 00:00:00
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更新日期:1991-07-01 00:00:00
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doi:10.1203/00006450-198408000-00018
更新日期:1984-08-01 00:00:00
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doi:10.1203/00006450-199904010-00017
更新日期:1999-04-01 00:00:00
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journal_title:Pediatric research
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更新日期:2000-12-01 00:00:00
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journal_title:Pediatric research
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更新日期:2013-01-01 00:00:00
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journal_title:Pediatric research
pub_type: 杂志文章
doi:10.1203/00006450-198506000-00019
更新日期:1985-06-01 00:00:00
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更新日期:2006-02-01 00:00:00
abstract::Based on the serum phenylalanine levels under free diet patients with hyperphenylalaninemia are classified as "classical" (>1200 micromol/L), "mild" (600-1200 micromol/L), or "non-phenylketonuria (PKU)-hyperphenylalaninemia" (<600 micromol/L). Recent studies revealed intellectual, neurologic, and neuropsychologic defi...
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更新日期:1997-09-01 00:00:00