Repetitive transcranial magnetic stimulation reduces cigarette consumption in schizophrenia patients.

Abstract:

INTRODUCTION:High-frequency repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) seemed to decrease tobacco consumption and craving in nicotine-dependent people without psychiatric disorder or otherwise healthy people. Even if the prevalence of cigarette smoking in schizophrenia patients is high and estimated to be between 45% and 88%, this technique has not been systematically studied in this indication in schizophrenia yet. THE AIM OF THE STUDY:The aim of this study was to test the ability of high-frequency (10Hz) rTMS over the left DLPFC to decrease cigarette consumption in schizophrenia patients. METHODS:The study included 35 male schizophrenia patients on stable antipsychotic medication. The patients were divided into two groups: the first (18 patients) were actively stimulated and the second (17 patients) underwent sham (placebo) stimulation. The sham rTMS was administered using a purpose-built sham coil that was identical in appearance to the real coil and made the same noise but did not deliver a substantial stimulus. The rTMS was administered at the stimulation parameters: location (left dorsolateral prefrontal cortex: DLPFC), intensity of magnetic stimulation in % of motor threshold (110%), stimulation frequency (10Hz), number of trains (20), single train duration (10s), inter-train interval (30s), and total number of stimulation sessions (21). In each stimulation session, 2000TMSpulses were given, with a total of 42,000pulses per treatment course. Patients noted the number of cigarettes smoked in the 7days before treatment, during the whole stimulation treatment (21days), and again for a 7-day period after treatment. RESULTS:Cigarette consumption was statistically significantly lower in the actively stimulated patients than in the sham rTMS group as early as the first week of stimulation. No statistically relevant correlations were found in the changes of ongoing negative or depressive schizophrenia symptoms and the number of cigarettes smoked. CONCLUSION:High-frequency rTMS over the left DLPFC has the ability to decrease the number of cigarettes smoked in schizophrenia patients.

authors

Prikryl R,Ustohal L,Kucerova HP,Kasparek T,Jarkovsky J,Hublova V,Vrzalova M,Ceskova E

doi

10.1016/j.pnpbp.2013.10.019

subject

Has Abstract

pub_date

2014-03-03 00:00:00

pages

30-5

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(13)00241-8

journal_volume

49

pub_type

杂志文章,随机对照试验
  • Using model fish to study the biological mechanisms of cooperative behaviour: A future for translational research concerning social anxiety disorders?

    abstract::Human societies demand of its composing members the development of a wide array of social tools and strategies. A notable example is human outstanding ability to cooperate with others, in all its complex forms, depicting the reality of a highly demanding social framework in which humans need to be integrated as to att...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.pnpbp.2017.11.014

    authors: Soares MC,Cardoso SC,Carvalho TDS,Maximino C

    更新日期:2018-03-02 00:00:00

  • Prospective strategies for cholinergic interventions in Alzheimer's disease.

    abstract::The cholinergic hypothesis of memory dysfunction has guided most of the recent proposals for treating the primary symptoms of AD. The efficacy of these treatments has been severely limited. This review examines two major lines of evidence which suggest that the cholinergic hypothesis may have to be expanded and revise...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/0278-5846(86)90025-4

    authors: Pomara N,Bagne CA,Stanley M,Yarbrough GG

    更新日期:1986-01-01 00:00:00

  • DRD4 gene and obsessive compulsive disorder: do symptom dimensions have specific genetic correlates?

    abstract:INTRODUCTION:The dopamine D4 receptor (DRD4) is a promising candidate gene in obsessive compulsive disorder (OCD). A 48-bp variable number of tandem repeats (VNTR) sequence in exon 3 has been studied previously, and alleles containing 2-11 repeats (2R-11R) have been identified. We investigated the association of DRD4 V...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2012.10.023

    authors: Taj M J RJ,Viswanath B,Purushottam M,Kandavel T,Janardhan Reddy YC,Jain S

    更新日期:2013-03-05 00:00:00

  • Disrupted dynamic local brain functional connectivity patterns in generalized anxiety disorder.

    abstract::Previous studies have reported abnormalities in static brain activity and connectivity in patients with generalized anxiety disorder (GAD). However, the dynamic patterns of brain connectivity in patients with GAD have not been fully explored. In this study, we aimed to investigate the dynamic local brain functional co...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2019.109833

    authors: Cui Q,Chen Y,Tang Q,Han S,Hu S,Pang Y,Lu F,Nan X,Sheng W,Shen Q,Wang Y,He Z,Chen H

    更新日期:2020-04-20 00:00:00

  • A proton spectroscopy study of white matter in children with autism.

    abstract::White matter abnormalities have been described in autism spectrum disorder (ASD) with mounting evidence implicating these alterations in the pathophysiology of the aberrant connectivity reported in this disorder. The goal of this investigation is to further examine white matter structure in ASD using proton magnetic r...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2015.11.005

    authors: Hardan AY,Fung LK,Frazier T,Berquist SW,Minshew NJ,Keshavan MS,Stanley JA

    更新日期:2016-04-03 00:00:00

  • Effect of R-(-)-alpha-methylhistamine and thioperamide on in vivo release of norepinephrine in the rat hippocampus.

    abstract::1. The modifications of hippocampal release of norepinephrine following the administration of R-(-)-alpha-methylhistamine and thioperamide, respectively agonist and antagonist of histamine H3 receptors, were assessed in freely moving rats by microdialysis. 2. Both the systemic (2 mg/kg i.p.) and local (100 microM via ...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/s0278-5846(99)00093-7

    authors: Di Carlo G,Ghi P,Orsetti M

    更新日期:2000-02-01 00:00:00

  • Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables.

    abstract:BACKGROUND:Intent-to-treat analyses from a randomized controlled trial showed significant between-group differences favouring micronutrient treatment on the Clinical Global Impression-Improvement, but no group differences on clinician, parent and teacher ratings of overall ADHD symptoms. There was an advantage of micro...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pnpbp.2018.09.007

    authors: Rucklidge JJ,Eggleston MJF,Darling KA,Stevens AJ,Kennedy MA,Frampton CM

    更新日期:2019-03-08 00:00:00

  • Citalopram for social phobia: a clinical case series.

    abstract::Social anxiety disorder is a common illness with significant associated disability. Serotonin selective reuptake inhibitors (SSRIs) have become first-line treatment given their improved tolerability; however, there are few reports on the use of citalopram. Nine consecutive patients with a primary diagnosis of DSM-IV g...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/s0278-5846(01)00189-0

    authors: Simon NM,Sharma SG,Worthington JJ,Marzol PC,Pollack MH

    更新日期:2001-10-01 00:00:00

  • Neurocognitive deficits and quality of life in outpatients with schizophrenia.

    abstract::The purpose of this cross-sectional study was to examine the relationships between neurocognitive deficits and quality of life for patient with schizophrenia. Fifty-seven schizophrenic outpatients (38 men and 19 women) were assessed for neurocognitive deficits using the Wisconsin Card Sorting Test (WCST) and all patie...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0278-5846(02)00217-8

    authors: Aksaray G,Oflu S,Kaptanoğlu C,Bal C

    更新日期:2002-10-01 00:00:00

  • Accelerated apoptosis of blood leukocytes and oxidative stress in blood of patients with major depression.

    abstract::Acceleration of blood leukocyte apoptosis in major depression has been described. The present studies have been undertaken to estimate the level of apoptosis of blood leukocytes in patients with depression and to examine the mechanisms leading to apoptosis. Blood was taken from 29 patients with depression (age 48.2+/-...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2007.11.012

    authors: Szuster-Ciesielska A,Słotwińska M,Stachura A,Marmurowska-Michałowska H,Dubas-Slemp H,Bojarska-Junak A,Kandefer-Szerszeń M

    更新日期:2008-04-01 00:00:00

  • Early life social experience affects adulthood fear extinction deficit and associated dopamine profile abnormalities in a rat model of PTSD.

    abstract::Individuals may develop fear extinction deficits after life-threatening traumatic events; such deficits indicate posttraumatic stress disorder (PTSD). Because the occurrence of this disorder differs among people who have experienced trauma, hidden underlying factors should be determined. Increasing evidence suggests t...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2020.109914

    authors: Lin CC,Chen TY,Cheng PY,Liu YP

    更新日期:2020-07-13 00:00:00

  • Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.

    abstract::Sildenafil, a selective phosphodiesterase 5 (PDE5) inhibitor, has recently been reported to affect convulsant activity in some animal models of seizures and epilepsy. Moreover, its influence on the protective activity of some antiepileptic drugs (AEDs) was also noted. The aim of the present study was to investigate th...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2012.05.020

    authors: Nieoczym D,Socała K,Luszczki JJ,Czuczwar SJ,Wlaź P

    更新日期:2012-10-01 00:00:00

  • Anxiety and beta-adrenergic receptor function in a normal population.

    abstract::Many studies have shown a close relationship between anxiety and beta-adrenergic receptor function in patients with anxiety disorders. This study examined the relationship between beta-adrenergic receptor function and anxiety levels in a normal population. Subjects for this study included 36 men and 44 women between t...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.pnpbp.2005.04.027

    authors: Kang EH,Yu BH

    更新日期:2005-06-01 00:00:00

  • Neural correlates of negative emotion processing in bipolar disorder.

    abstract:INTRODUCTION:Bipolar disorder type I (BD-I) is characterized by a severe impairment in emotional processing during both acute and euthymic phases of the illness. The aim of the present study was to investigate negative emotion processing in both euthymic patients and non-affected first-degree relatives, looking for sta...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2015.01.016

    authors: Sepede G,De Berardis D,Campanella D,Perrucci MG,Ferretti A,Salerno RM,Di Giannantonio M,Romani GL,Gambi F

    更新日期:2015-07-03 00:00:00

  • A common polymorphism in the 3'-UTR of the NOS1 gene was associated with completed suicides in Japanese male population.

    abstract:BACKGROUND:Suicidal behavior has been widely accepted as familial. Its transmission cannot be explained by the transmission of psychiatric disorder alone and seems to be partly explained by the transmission of impulsive-aggressive behavior. Studies in laboratory animal have shown that mice lacking NOS1 manifest signifi...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2010.04.028

    authors: Cui H,Supriyanto I,Asano M,Ueno Y,Nagasaki Y,Nishiguchi N,Shirakawa O,Hishimoto A

    更新日期:2010-08-16 00:00:00

  • Abnormal long- and short-range functional connectivity in adolescent-onset schizophrenia patients: A resting-state fMRI study.

    abstract:BACKGROUND:Human brain is a topologically complex network embedded in anatomical space, and anatomical distance may affect functional connectivity (FC) in schizophrenia. However, little is known if and how this effect occurs in adolescent-onset schizophrenia (AOS). METHODS:We explored long- and short-range FC through ...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2017.08.012

    authors: Wang S,Zhan Y,Zhang Y,Lyu L,Lyu H,Wang G,Wu R,Zhao J,Guo W

    更新日期:2018-02-02 00:00:00

  • Methadone is substantially less effective than morphine in modifying locomotor and brain Fos responses to subsequent methadone challenge in rats.

    abstract::Heroin addicts can benefit from methadone substitution therapy. However, little is known about the significance of pre-exposure to opioids for psychoactive effects of methadone. We modeled some behavioral and neurobiological aspects of the opioid abuse-related phenomena in Sprague-Dawley rats, using morphine (10 mg/kg...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2009.05.015

    authors: Taracha E,Chrapusta SJ,Lehner M,Skórzewska A,Płaźnik A

    更新日期:2009-08-31 00:00:00

  • Limbic control of aggression in the cat.

    abstract::Over a decade of work by Flynn and colleagues has delineated a network of limbic circuits which function to modulate the expression of predatory aggression and defence in the cat, and aspects of this work are reviewed. In particular, Flynn's work revealed a circuit involving the basomedial amygdala which functions to ...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/0278-5846(83)90017-9

    authors: Adamec RE,Stark-Adamec CI

    更新日期:1983-01-01 00:00:00

  • Staging and profiling for schizophrenia spectrum disorders: Inter-rater reliability after a short training course.

    abstract:OBJECTIVE:Clinical staging and profiling have been proposed as a new approach in order to refine the diagnostic assessment of schizophrenia spectrum disorders. However, only limited evidence is available for the inter-rater reliability of the clinical staging and profiling model. The aim of the present study was theref...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2019.109856

    authors: Berendsen S,van der Paardt JW,Van HL,van Bruggen M,Nusselder H,Jalink M,de Peuter OR,Peen J,van Tricht MJ,de Haan L

    更新日期:2020-04-20 00:00:00

  • Neurocognitive function in borderline personality disorder.

    abstract::A battery of neuropsychological measures considered sensitive to dysfunction in prefrontal or temporal cortices was administered to patients with borderline personality disorder (BPD) and healthy controls. BPD patients exhibited striking deficits on measures of nonverbal executive function and nonverbal memory but wer...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2003.10.012

    authors: Dinn WM,Harris CL,Aycicegi A,Greene PB,Kirkley SM,Reilly C

    更新日期:2004-03-01 00:00:00

  • Prevalence of anxiety in health care professionals during the COVID-19 pandemic: A rapid systematic review (on published articles in Medline) with meta-analysis.

    abstract::During the COVID-19, healthcare workers are exposed to a higher risk of mental health problems, especially anxiety symptoms. The current work aims at contributing to an update of anxiety prevalence in this population by conducting a rapid systematic review and meta-analysis. Medline and Pubmed were searched for studie...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2021.110244

    authors: Santabárbara J,Bueno-Notivol J,Lipnicki DM,Olaya B,Pérez-Moreno M,Gracia-García P,Idoiaga-Mondragon N,Ozamiz-Etxebarria N

    更新日期:2021-01-14 00:00:00

  • The treatment and management of neuroleptic malignant syndrome.

    abstract::1. The neuroleptic malignant syndrome was initially described as a disorder specifically related to neuroleptic usage with frequent fatal outcome. The observations of variant or mild cases of this syndrome as well as case reports on neuroleptic-malignant-like syndromes in the absence of neuroleptics raises the issue o...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/0278-5846(92)90051-f

    authors: Gratz SS,Levinson DF,Simpson GM

    更新日期:1992-07-01 00:00:00

  • Gamma-aminobutyric acid and mefloquine-induced seizures in mice.

    abstract::The role of GABAergic mechanism in the convulsant effect of mefloquine was investigated in mice. Mefloquine dose dependently induced tonic seizures in mice. Aminooxyacetic acid, diaminobutyric acid and muscimol significantly protected mice against mefloquine-induced seizures by significantly delaying the onset and dec...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2005.04.030

    authors: Amabeoku GJ,Farmer CC

    更新日期:2005-07-01 00:00:00

  • Pathophysiology in the comorbidity of Bipolar Disorder and Alzheimer's Disease: pharmacological and stem cell approaches.

    abstract::Neuropsychiatric disorders involve various pathological mechanisms, resulting in neurodegeneration and brain atrophy. Neurodevelopmental processes have shown to be critical for the progression of those disorders, which are based on genetic and epigenetic mechanisms as well as on extrinsic factors. We review here commo...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.pnpbp.2017.04.033

    authors: Corrêa-Velloso JC,Gonçalves MC,Naaldijk Y,Oliveira-Giacomelli Á,Pillat MM,Ulrich H

    更新日期:2018-01-03 00:00:00

  • Epigenetic and genetic variants in the HTR1B gene and clinical improvement in children and adolescents treated with fluoxetine.

    abstract::The serotonin 1B receptor (5-HT1B) is important to both the pathogenesis of major depressive disorder and the antidepressant effects of selective serotonin reuptake inhibitors. Although fluoxetine has been shown to be effective and safe in children and adolescents, not all patients experience a proper clinical respons...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2016.12.003

    authors: Gassó P,Rodríguez N,Blázquez A,Monteagudo A,Boloc D,Plana MT,Lafuente A,Lázaro L,Arnaiz JA,Mas S

    更新日期:2017-04-03 00:00:00

  • A new risk locus in the ZEB2 gene for schizophrenia in the Han Chinese population.

    abstract::The ZEB2 gene encodes the Zinc Finger E-box binding protein. As a key regulator of epithelial mesenchymal differentiation, ZEB2 plays an important role in the pathogenesis of cancer, and its high level expression has been observed in glioma patients. Different mutations in this gene have been identified in patients wi...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2015.12.001

    authors: Khan RAW,Chen J,Wang M,Li Z,Shen J,Wen Z,Song Z,Li W,Xu Y,Wang L,Shi Y

    更新日期:2016-04-03 00:00:00

  • Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression.

    abstract::Aggressive behavior is one of the most challenging symptoms in psychiatry, and biological markers for aggression lack of large sample validations. Serotonin (5-HT) and other neuroactive compounds deriving from Tryptophan (Trp), including kynurenine (Kyn), have not yet been investigated in large cohorts of aggressive i...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.pnpbp.2016.04.012

    authors: Comai S,Bertazzo A,Vachon J,Daigle M,Toupin J,Côté G,Turecki G,Gobbi G

    更新日期:2016-10-03 00:00:00

  • Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association.

    abstract::The aim of the present study was to develop an animal model for the study of depressive symptoms associated with Parkinson's disease (PD). Mice treated intraperitoneally with reserpine (RES), 2.0 and 1.0 mg/kg, or its vehicle (VEHIC) were submitted to the sucrose solution (2%) consumption test (a model employed to mim...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/s0278-5846(01)00333-5

    authors: Skalisz LL,Beijamini V,Joca SL,Vital MA,Da Cunha C,Andreatini R

    更新日期:2002-06-01 00:00:00

  • Monoamine neurocircuitry in depression and strategies for new treatments.

    abstract::Extensive studies showed that monoaminergic neurotransmission that involves serotonin (5-HT), norepinephrine (NE) and dopamine (DA) exerts major influence on brain circuits concerned by the regulation of mood, reactivity to psychological stress, self-control, motivation, drive, and cognitive performance. Antidepressan...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.pnpbp.2013.04.009

    authors: Hamon M,Blier P

    更新日期:2013-08-01 00:00:00

  • Impact of blue vs red light on retinal response of patients with seasonal affective disorder and healthy controls.

    abstract:OBJECTIVES:Seasonal affective disorder (SAD) is characterized by a mood lowering in autumn and/or winter followed by spontaneous remission in spring or summer. Bright light (BL) is recognized as the treatment of choice for individuals affected with this disease. It was speculated that BL acts on photosensitive retinal ...

    journal_title:Progress in neuro-psychopharmacology & biological psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pnpbp.2010.11.009

    authors: Gagné AM,Lévesque F,Gagné P,Hébert M

    更新日期:2011-01-15 00:00:00