Dependence between apolipoprotein E phenotypes and temperament in children, adolescents, and young adults.

Abstract:

:The association of apolipoprotein E (apoE) polymorphism with temperament and Type A behavior was studied in 1577 randomly selected healthy children, adolescents, and young adults during a follow-up period of 9 years. Temperament was correlated with apoE phenotypes. Motor activity, even hyperactivity, in childhood and mental vitality in adolescence and young adulthood increased significantly with the apoE phenotypes in the order of E2/2, E3/2, E4/2, E3/3, E4/3, and E4/4. However, global Type A behavior was not associated with the order of apoE phenotypes. The findings suggest the importance of additional studies on genetic factor and temperament.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Keltikangas-Järvinen L,Räikkönen K,Lehtimäki T

doi

10.1097/00006842-199303000-00004

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

155-63

issue

2

eissn

0033-3174

issn

1534-7796

journal_volume

55

pub_type

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