Abstract:
:The authors review the knowledge accumulated on animal models of diabetes during the last decade. The most commonly used diabetes models and the underlying disease processes are summarized, respectively. The best known diabetogenic substances, Streptozotocin and Alloxan are described, including their usage, dosage dosing intervals, and mechanism of action. The latest results are included in the article which discuss the possible role of free radical-induced injury of beta cells in Streptozotocin and Alloxan diabetes.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Pusztai P,Prechl J,Somogyi A,Szaleczky E,Fehér Jsubject
Has Abstractpub_date
1996-08-25 00:00:00pages
1865-9issue
34eissn
0030-6002issn
1788-6120journal_volume
137pub_type
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