Abstract：
BACKGROUND:Neoadjuvant therapy has improved outcomes for patients with locally advanced rectal cancer. AIM AUTHORS: We studied the degree of histopathological regression after radiotherapy regimens commonly used in their clinical practice, and its effect on the pathology of by clinically founded T3-T4 rectal cancer. PATIENT AND METHODS:A total of 57 patients were investigated who underwent neoadjuvant radiotherapy or chemoradiotherapy--commonly used at our institute--for biopsy proven primary mid or lower third rectum adenocarcinoma between January and December 2004. The standard surgical treatment was anterior resection sec Dixon, Lloyd-Davies--and Hartmann's procedure, all with total mesorectal excision. RESULTS:The surgical specimens were examined by selected pathologists and a modified pathologic staging system the Rectal Cancer Regression Grade (RCRG) was used. (I) "good" response (n=12, 21%), (II) "median" response (n=25, 44%), (III) "poor" response (n=20, 35%). Significant tumor regression (RCRG I-II.) was seen in 37 patients (65%). Six patients (10.5%) have had complete pathological regression and 6 patients (10.5%) have had only microscopic foci of adenocarcinoma. CONCLUSION:Comparing of pretreatment and pathologic staging revealed that the depth of invasion was significantly downstaged. The authors also reviewed the literature of neoadjuvant therapy, total mesorectal excision, prognostic and predictive factors of rectal cancer.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Mátrai Z,Lövey J,Hitre E,Orosz Z,Gödény M,Péley G,Sulyok Z,Rényi Vámos F,Farkas E,Köves Isubject
Has Abstractpub_date
2006-10-22 00:00:00pages
2011-20issue
42eissn
0030-6002issn
1788-6120journal_volume
147pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract：:The authors report about the elimination of foreign bodies fixed in the oesophagus and aspirated into the right main bronchus. They discuss the diagnostic work and the ways of its elimination. They emphasize the importance of cooperation between the endoscopist and the surgeon. ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1992-07-12 00:00:00
abstract：:No effective medical therapies have been developed sofar to enhance blood flow in the legs of patients with peripheral arterial disease (PAD). For patients with limb threatening ischaemia the only option for relief of rest pain or gangraena is amputation. There is evidence in experimental and clinical studies that adu...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2006-06-25 00:00:00
abstract：:This paper describes a case of an epidermoid cyst arising in the anterior wall of the coecum. Epidermoid and dermoid cysts of the coecum are exceptionally rare. These cysts arise by the sequestration of squamous epithelium during embryological development, or following trauma or surgery. The true cysts are the result ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2001-07-22 00:00:00
abstract：INTRODUCTION:The mortality rate from sepsis is high and the risk of sepsis increases in prematurity in proportion to the decrease in birth weight. MATERIAL AND METHOD:The authors report the assessment of serum interleukin-6 levels in 12 term, at-risk newborn infants after birth and 60 VLBW neonates after detection of ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2007.27991
更新日期：2007-08-26 00:00:00
abstract：:Ulcerative colitis seldom associated with nutritive and/or salicylate allergy. Authors present a case of both allergic events at the course of the disease. In 1996 a 19-year-old girl was referred with a history of blood in stool as well as diarrhoea, suggesting ulcerative proctitis. Biopsy revealed ulcerative colitis ...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2004-10-31 00:00:00
abstract：:Endoscopic ultrasound is the most accurate imaging modality for the diagnosis of pancreatic cancer, and endoscopic ultrasound-guided fine needle injection has already been used for palliative interventions. Surgical resection is currently the standard treatment for pancreatic insulinoma. Medical treatment may be neces...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2014.30012
更新日期：2014-10-12 00:00:00
abstract：:The authors review two cases of suspected congenital cytomegalovirus (CMV) infections in which modern laboratory approaches were applied to establish the diagnosis postnatally. In the first case, intrauterine infection was suggested by ventriculomegaly, detected by means of a head ultrasonographic scan. The postnatal ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2004-04-25 00:00:00
abstract：:In the past few years, ultrasonography has become the most widespread and easily available diagnostic procedure in gynecological practice. the high-frequency transvaginal probe provides a detailed visualization of the reproductive organs and the urinary bladder. however, in spite of this generally applied examination ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2005-02-27 00:00:00
abstract：:The simultaneous recording of urodynamic parameters and x-ray imaging of the lower urinary tract is the ideal technique for a complex investigation of the lower urinary tract morphology and function. The urodynamic and micturating cystourethrography findings were reviewed in 57 children. The causes of the examinations...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1992-12-20 00:00:00
abstract：:Chronic obstructive pulmonary disease is often associated with cardiovascular diseases, such as pulmonary hypertension, ischemic heart disease, arrhythmias or heart failure. These co-morbidities may cause diagnostic or therapeutic difficulties and significantly worsen the morbidity and mortality of patients with chron...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2014.29989
更新日期：2014-09-14 00:00:00
abstract：:Authors present a case of twin intrauterine pregnancy combined with ectopic pregnancy. The simultaneous pregnancies occurred after the use of clomiphene citrate. In this case viable intrauterine twin gestation was observed by vaginal ultrasound examination, the simultaneous ectopic pregnancy was observed by laparotomy...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：2000-10-08 00:00:00
abstract：:A case of eosinophilic gastritis is reported in a 65-year-old woman. The disease presented with signs of delayed emptying, vomiting and substantial thickening of the antrum. Partial gastrectomy was performed because of the suspicion of gastric cancer and pyloric stenosis. Histopathology established the diagnosis of eo...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2003-03-16 00:00:00
abstract：:The patients' attitudes towards kidney transplantation are significantly affected by the acceptance of the treatment to have a better quality of life. Exploration of the cognitive-emotional relation in patients with chronic renal failure. Our study included 285 kidney patients. We investigated three groups of patients...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/650.2018.31283
更新日期：2018-11-01 00:00:00
abstract：UNLABELLED:Rheumatoid arthritis (RA) is a chronic, progressive polyarthritis leading to substantial disability. Standardised data on consequences of disease progression are needed for clinical assessments and also for cost-effectiveness models. AIM:To analyse the impact of disease progression on health status, disease...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2008.28294
更新日期：2008-04-20 00:00:00
abstract：:The author analyzes the applicability of the renin-angiotensin system blocking drugs in patients with chronic kidney disease emphasizing their renoprotective (blood pressure and albuminuria lowering) and cardiovascular risk decreasing effects. As opposed to a previously-published statement, the author believes that th...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2013.29609
更新日期：2013-05-12 00:00:00
abstract：:Authors present a method of esophageal dilatation and report their experiences. The place of esophageal dilatation among other therapeutic approaches of esophageal stricture is discussed. The advantage of Savary-Gilliard bougies and guide wire and its applications are presented. During one and a half year 218 esophage...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1992-11-15 00:00:00
abstract：:Endotoxin concentrations were measured in the portal, hepatic venous blood and abdominal aorta of six groups of rats in experimental alcoholic liver injury. Groups of animal consisted of 16 rats: I.: control group; II.: rats received one dose of E. coli 0127: B8-3 mg/kg intraperitoneally (i.p.), III.: rats received th...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1994-07-31 00:00:00
abstract：:It is has been widely studied and proved that obstructive sleep apnea is a risk factor for cardiovascular diseases, especially hypertension, myocardial infarction and stroke. It is also important to be aware that, due to sleep apnea, hypersomnia increases the risk of accidents and the prevalence of neuropsychiatric co...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2010.28948
更新日期：2010-10-17 00:00:00
abstract：:Around 25% of medullary thyroid carcinoma (MTC) cases are familial and follow an autosomal dominant mode of inheritance. In these cases, MTC is part of an inherited cancer syndrome that has three distinct forms: MEN2A, MEN2B and familial MTC (FMTC). MEN2A is the most frequent syndrome, followed by FMTC and MEN2B. In 9...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1999-12-05 00:00:00
abstract：:The results of a pilot study of head and neck lymphoscintigraphy are presented. The study was performed in 35 cases with technetium-99m-labelled microcolloid. The scintigraphic observations of the intact and tumorous neck are presented. The results of this pilot study suggest that this method might create the base of ...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1990-09-16 00:00:00
abstract：:Nijmegen Breakage syndrome is a rare, autosomal recessive disorder characterized by severe, combined immunodeficiency, recurrent sinopulmonary infections, chromosomal instability, radiosensitivity, predisposition to malignancy, a "bird-like" facial appearance, progressive microcephaly, short stature, and mental retard...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/OH.2010.28851
更新日期：2010-04-18 00:00:00
abstract：:Prevalence of antibodies to variants HHV-6A and B as well as HHV-7, the time of primary infections are not know in Hungarian children. Therefore, antibodies to these viruses were studied in 21 healthy children aged between 6 and 18 months. Lymphoid cultures were infected with standard virus strains for indirect immuno...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-25 00:00:00
abstract：:The left ventricular stroke volume was determined in 15 healthy male volunteers of the same age (21-23 yrs). The systolic function was characterized by six, the diastolic function by five parameters. The diameter and the cross-sectional areas of the outflow tract were determined. Intraobserver, interobserver and day-t...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1989-08-20 00:00:00
abstract：:The surgical management of congenital heart defects is changing continuously due to technical development. Aortic coarctation is one of the most frequent congenital heart diseases often with serious symptoms. The authors review the different surgical techniques (end-to-end anastomosis, pathplasty, interposition) and p...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：10.1556/650.2020.31730
更新日期：2020-05-01 00:00:00
abstract：:Chromosome studies were carried out on 112 children with acute leukemia and 10 children with solid tumor. Acquired chromosome abnormalities were identified shown in 52% of patients with hematologic disorders (ALL 40%, ANLL 64%) and in four of 10 patients with non-hematologic disorders. Six patients had a constitutiona...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1996-02-04 00:00:00
abstract：:The authors report on the case history of a three-month-old infant with Kawasaki-syndrome. The course of the disease was atypical, the various symptoms (antibiotic resistant high fever, urticariform rash, meningitis serosa, steril pyuria, coronaria aneurysma, thrombocytosis, high sedimentation rate) developed slowly d...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：1995-09-17 00:00:00
abstract：:The advances in molecular genetic methods has lead to the discovery of the genetic alterations that underlie the etiology of most diseases previously held to be idiopathic. Targeted genetic examination of a pediatric male patient showing a normal intellect, an extended area of skin hypopigmentation, and suffering from...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/650.2019.31404
更新日期：2019-05-01 00:00:00
abstract：UNLABELLED:The health status and social circumstances of medical professionals have been studied worldwide. However, there are only a few published studies pertaining to these topics in the countries of the former Eastern block. The present paper aimed at charting the state of health, the medical career path and some s...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：10.1556/OH.2009.28566
更新日期：2009-03-22 00:00:00
abstract：:The authors present a case of acute dissection of ascending aorta diagnosed by two-dimensional echocardiography. Echocardiographic findings were subsequently confirmed by angiography. The patient was successfully operated and has been asymptomatic since the operation. The authors point out the importance the echocardi...
journal_title：Orvosi hetilap
pub_type： 杂志文章,评审
doi：
更新日期：1989-02-26 00:00:00
abstract：:The treatment of atrial tachycardia in critically ill patients can be difficult. Nine cases were presented with atrial tachyarrhythmias (mean heart rate > 130 beats/min) and left heart failure. Congestive heart failure was diagnosed in 6 patients (ejection fraction < 25%) and hypertensive heart failure in 3 patients (...
journal_title：Orvosi hetilap
pub_type： 杂志文章
doi：
更新日期：2001-12-30 00:00:00
