Umbilical cord plasma cortisol levels in association with pregnancy complications.

Abstract:

:Cortisol concentrations in umbilical cord plasma at birth were determined in association with pregnancy complications which may affect the time of pulmonary maturation of the fetus or otherwise influence its survival. No statistically significant change in these cortisol levels was observed in either term or premature pregnancies with the following complications: maternal disorder (preeclampsia, diabetes, pruritus), prolonged rupture of membranes, antenatal isoxsuprine treatment, maternal cigarette smoking, and neonatal asphyxia. Significant increases were observed in premature births in association with intrauterine fetal growth retardation and with the appearance of meconium. Cortisol concentrations in more severe forms of diabetes were significantly less than in Class A diabetes, in premature cases, and also tended to be low in association with various fetal congenital abnormalities. The possible physiologic significance of these results is discussed.

journal_name

Obstet Gynecol

authors

Sybulski S

subject

Has Abstract

pub_date

1977-09-01 00:00:00

pages

308-12

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

50

pub_type

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