Tandem ureteral stents for the decompression of malignant and benign obstructive uropathy.

Abstract:

PURPOSE:To evaluate the utility of two ipsilateral ureteral stents placed for benign and malignant ureteral obstruction. METHODS:We performed a retrospective analysis of all cases of tandem ureteral stent (TUS) insertion at our institution from July 2007 through January 2013. Student t, Fisher exact, and log-rank test were used. RESULTS:TUS insertion or exchange was performed in 187 cases. There were 66 patients (75 renal units) who underwent successful TUS insertion. Malignant ureteral obstruction (MUO) was the cause for obstruction in 39 renal units (34 patients) vs benign ureteral obstruction (BUO) in 36 renal units (32 patients). Four patients with BUO and 15 patients with MUO underwent stent exchanges at a mean 145 and 128 days, respectively. Serum creatinine levels were stable poststent placement (P=0.4). Degree of hydronephrosis improved (paired t test P<0.03) after stent placement for both benign and malignant cohorts. TUS placement was noted to fail (flank pain with worsening hydronephrosis or increasing creatinine level) in five renal units with MUO (12.8%) and none with BUO. Stent failure (either conventional or TUS) suggested worsening survival in those with MUO. Median survival for those with MUO and a history of stent failure (10 of 14 died, 71%) was 66 days compared with 432 days for those without a history of stent failure (8 of 20 died, 40%) (log-rank test P=0.007). CONCLUSION:Our experience with the TUS, the largest to date, demonstrated that they are highly successful in both benign and malignant causes of obstruction, comparing favorably with metallic ureteral stents. Stent failure may be predictive for shorter survival.

journal_name

J Endourol

journal_title

Journal of endourology

authors

Elsamra SE,Motato H,Moreira DM,Waingankar N,Friedlander JI,Weiss G,Smith AD,Okeke Z

doi

10.1089/end.2013.0281

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

1297-302

issue

10

eissn

0892-7790

issn

1557-900X

journal_volume

27

pub_type

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