Abstract:
: Background: Holmium laser enucleation of the prostate (HoLEP) is a highly effective procedure for benign prostatic hyperplasia that is size independent and has been recommended for patients necessitating antiplatelet (AP) and anticoagulant (AC) medications. Although HoLEP is feasible in AP/AC patients, there is a lack of published results on real-world outcomes of patients on AP/AC therapy undergoing HoLEP. Patients and Methods: We performed a retrospective review of our institutional HoLEP database of demographics, perioperative and postoperative data, and outcomes of patients on AP and AC therapy compared with none. We also further stratified patients on warfarin compared with direct oral anticoagulants (DOACs). Results: Of 472 patients who underwent HoLEP at our institution from July 2018 to December 2019 with data on AP/AC drugs, 30 (6.3%) were on AP and 65 (17.2%) were on AC. One patient continued AP (3.3%), six patients (9.2%) were bridged on AC, and one patient (1.5%) continued AC through the time of HoLEP at the discretion of the prescribing provider. Preoperatively, only age was significantly different among the three groups (p < 0.001). There were no intraoperative differences. Postoperatively, there was a higher 90-day complication rate in AP and AC groups (p = 0.035), but not an increase in emergency department (ED) visits (p = 0.557) or Clavien ≥3 complications (p = 0.16). In comparison of patients on warfarin with DOAC, there was a lower rate of successful voiding trial (p = 0.009), higher 90-day complications (p = 0.003), and more ED visits (p = 0.003) in the warfarin group. Conclusions: HoLEP is safe and effective for patients who require AP or AC therapy. There is no increase in serious complications or worsened postoperative voiding parameters. Of patients on AC, those on DOAC have better outcomes compared with warfarin.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Agarwal DK,Large T,Stoughton CL,Heiman JM,Nottingham CU,Rivera ME,Krambeck AEdoi
10.1089/end.2020.0886subject
Has Abstractpub_date
2021-01-06 00:00:00eissn
0892-7790issn
1557-900Xpub_type
杂志文章abstract:PURPOSE:Safe insertion of the first port during laparoscopic surgery has always been problematic, from the early use of the Veress needle to the open Hasson technique. We describe a novel, safe, and well-illuminated technique of port entry using the Killian nasal speculum. This technique has been used successfully in t...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0142
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:This report describes a new animal model for research on the parameters of shockwave delivery and the mechanisms of shockwave action in SWL. MATERIALS AND METHODS:Female pigs (approximately 45 kg) were anesthetized for creation of an upper pole peripheral caliceal access. The tract was dilated with a 30F Nephr...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277902320913215
更新日期:2002-10-01 00:00:00
abstract:: Aims: To compare outcomes of monopolar vs bipolar transurethral resection of the prostate (TURP) in the management of exclusively moderate-large volume prostatic hyperplasia in terms of maximum flow rate as a surrogate for clinical efficacy, duration of catheterization, ho...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0840
更新日期:2020-12-28 00:00:00
abstract:PURPOSE:To compare the morbidity of percutaneous nephrolithotomy (PCNL) requiring multiple percutaneous tracts with that of procedures requiring a single tract for calculus clearance. PATIENTS AND METHODS:Data from 20 patients undergoing PCNL through two or more percutaneous renal tracts over a 1-year period were comp...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.753
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Development of flexible renoureteroscopy had a significant impact on the diagnosis and management of upper urinary tract pathology. The aim of our study was to compare the performances of a fiberoptic flexible ureteroscope (FFU) with those of a digital flexible ureteroscope (DFU). MATERIAL AND M...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0390
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The role of volumetric estimation is becoming increasingly important in the staging, management, and prognostication of benign and cancerous conditions of the kidney. We evaluated the use of three-dimensional reconstruction volume (3DV) in determining renal parenchymal volumes (RPV) and renal tum...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2013.0796
更新日期:2014-06-01 00:00:00
abstract:: Introduction: There has been a surge in robotic surgery research publications over the past 20 years. However, to date, there has been no characterization of urology's contribution to the robotic field, and there is a lack of bibliometric literature to guide future investi...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0866
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:Percutaneous nephrolithotomy (PNL) is established in urology practice with routine use of fluoroscopic guidance. Herein, we retrospectively evaluated the potential factors affecting the fluoroscopic screening time (FST) during PNL. MATERIALS AND METHODS:A total of 282 patients with documented FST in detail dur...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0256
更新日期:2009-11-01 00:00:00
abstract::Lumbar ureteral benign stenosis can be managed by laparoscopy. Prevention of repeat strictures after ureteral anastomosis includes the placement of a ureteral catheter. When laparoscopy is used to perform the anastomosis, a second position is needed to insert the Double J stent. We provide a way to place the double pi...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0153
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to evaluate if there is any advantage of three-dimensional helical computed tomography (3D-HCT) over intravenous urogram (IVU) in the morphometric and morphological analysis of lower pole spatial anatomy of the kidney. PATIENTS AND METHODS:We analyzed 52 renal collecting systems in 3...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2009.0262
更新日期:2009-12-01 00:00:00
abstract::The identification of calcium-binding proteins in urine and kidney stones has led to a closer look at the role of matrix proteins in urolithiasis. We analyzed five struvite stones for protein content and identified two bands (8 and 14 KDa) that were confirmed by gel electrophoresis and amino acid sequencing to be calg...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1994.8.95
更新日期:1994-04-01 00:00:00
abstract:AIM:To analyze the impact of slowing the shockwave delivery during extracorporeal shockwave lithotripsy (SWL) on the clinical patient outcome and the cost of delivering this service in a community practice. PATIENTS AND METHODS:The data from 1745 consecutive SWL procedures were analyzed at a freestanding surgery cente...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0656
更新日期:2010-09-01 00:00:00
abstract::Because of the high rate of ipsilateral multifocal disease and the low incidence of contralateral disease, upper tract transitional-cell carcinoma has historically been treated with radical nephroureterectomy. This operation has been performed laparoscopically in many medical centers, with various techniques. The diff...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.859
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with spinal neuropathy are at an increased risk for urolithiasis. Data on percutaneous nephrolithotomy (PCNL) in this population are limited. Our objective is to review our experience in managing stones with PCNL in patients with spinal neuropathy. PATIENTS AND METHODS:Twenty-one patien...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0344
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:There is a need to improve prescreening determination of prostate cancer to better select patients who need biopsy. Such a strategy properly implemented, will decrease the number of negative biopsies for prostate cancer and in turn better balance the risks and morbidity for patients recommen...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2013.0383
更新日期:2014-03-01 00:00:00
abstract::A 55-year-old man had a solid tumor in the right part of a horseshoe kidney. He had previously undergone open cholecystectomy and appendectomy with panperitonitis. Retroperitoneoscopic nephrectomy was performed, with rapid recovery and good short-term results. This appears to be the first case of endoscopic surgery on...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903772036253
更新日期:2003-12-01 00:00:00
abstract::Large bladder calculi are often outside the range of treatment with conventional endoscopic lithotrites because of either anatomic factors or the mechanical limits of available instruments. Alternative methods of cystolithotripsy: ultrasonic, electrohydraulic, or laser, can prove time-consuming or even hazardous, so t...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1994.8.183
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:To evaluate current practice patterns in U.S. emergency departments (EDs) for the diagnosis, treatment, and counseling of patients with ureteral calculi. METHODS:Hospital-based ED physicians were invited by e-mail to participate in a Survey-Monkey survey. E-mails were delivered in March 2008 by Direct Medica...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0615
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:With the evolution of endourologic technology, bilateral synchronous percutaneous nephrolithotomy (BS-PCNL) has emerged as a potentially practical intervention for patients with bilateral lithiasis. Although tradition has favored a staged approach, an increasing number of original studies have reported the...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.2016.0851
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To determine the effect of cryoablation on the collecting system in the porcine kidney and the possible development of pelvic injury or fistula. MATERIALS AND METHODS:Six kidneys from three domestic swine were utilized. Under MRI guidance, a 3-mm cryoprobe was placed percutaneously and advanced to a point adja...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903321196779
更新日期:2003-02-01 00:00:00
abstract:: Objective: To evaluate the safety of irreversible electroporation (IRE) for renal ablation adjacent to the ureter or bowel. Materials and Methods: Six adult pigs each underwent bilateral IRE of the kidney. To simulate adjacence...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0856
更新日期:2020-12-17 00:00:00
abstract:BACKGROUND AND PURPOSE:Retrograde ureteroscopic marsupialization is a pure natural orifice translumenal endoscopic surgery (NOTES). We retrospectively examined the feasibility and safety of this technique to manage symptomatic simple renal cysts. PATIENTS AND METHODS:Sixteen patients with simple renal cysts were selec...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0676
更新日期:2011-01-01 00:00:00
abstract::Twelve female microminipigs with normal bladder capacity underwent laparoscopic bladder seromyotomy. Three other female microminipigs were added to the study as controls. Urodynamic studies and cystograms were performed preoperatively and at 2 and 4 months after a laparoscopic bladder seromyotomy. Histologic studies o...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1996.10.267
更新日期:1996-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to measure the accuracy of stone-specific algorithms (S-mode) and the posterior acoustic shadow for determining kidney stone size with ultrasound (US) in vivo. MATERIALS AND METHODS:Thirty-four subjects with 115 renal stones were prospectively recruited and scanned with S-mode on ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0341
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:The impact of intrafascial versus interfascial nerve sparing during radical prostatectomy on oncologic and postoperative outcome is still controversial. This manuscript compares the outcomes of intrafascial versus interfascial techniques of nerve sparing used during robot-assisted laparoscopic radical pros...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0369
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To examine the effects of antibiotic prophylaxis on postoperative infection rate in patients with negative urine cultures undergoing ureteroscopy (URS). PATIENTS AND METHODS:Using the Clinical Research Office of the Endourological Society (CROES) URS Global Study database, patients with a negative baseline uri...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0470
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Laparoscopic urologic surgery is not widely practiced in South Africa. After presenting a laparoscopic training course, we evaluated how effectively this training translated into clinical practice. SUBJECTS AND METHODS:Invitations to the course were sent to all South African urologists. Ten appl...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2005.19.1180
更新日期:2005-12-01 00:00:00
abstract::The coronavirus disease 2019 (COVID-19) pandemic has had a global impact on all aspects of health care, including surgical procedures. For urologists, it has affected and will continue to influence how we approach the care of patients preoperatively, intraoperatively, and postoperatively. A risk-benefit assessment of ...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.2020.0342
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Telemedicine has become a common method for the transmission of images and patient data across long distances. Our goal was to assess the efficiency and accuracy of Photomailer MD software, a store-and-forward telemedicine system, in the urologic setting. METHODS:Photomailer MD software was loaded on two compu...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/end.1999.13.141
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The treatment of cystine stones is a clinical problem. This in vitro study was performed to establish an experimental system that enables standardized and reproducible investigations on chemolysis of cystine stones to look for an improvement of dissolution strategies. MATERIALS AND METHODS:Artif...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.451
更新日期:2000-06-01 00:00:00