Abstract:
BACKGROUND:Findings from the Life Span Study (LSS) of the health effects of exposure to atomic bomb radiation have documented a strong dose-response relation between radiation exposure and breast cancer incidence. PURPOSE:We analyzed data from the LSS cohort to identify nonradiation risk factors for breast cancer and to determine whether these factors were independent of the effects of radiation on breast cancer occurrence. METHODS:Breast cancer incidence was ascertained among a cohort of 22,200 residents of Hiroshima and Nagasaki, Japan, who had completed a mail survey between 1979 and 1981 to study nonradiation risk factors for disease. During the subsequent follow-up period (average 8.31 years), 161 cases of primary breast cancer were identified through population-based tumor registries in the two cities. RESULTS:The risk of breast cancer was inversely related to age at menarche and weakly positive in relation to age at menopause and years of menstruation. A significant negative association of full-term pregnancy against breast cancer was observed, although the number of pregnancies beyond the first was not related to the rate of breast cancer in the cohort. Women having their first full-term pregnancy before age 30 were at decreased risk of breast cancer relative to older women, but there was no trend. A nonsignificant, positive trend in risk was associated with increasing weight and body mass (kg/m2). The risk of breast cancer among women with a history of estrogen use was 1.64 (95% confidence interval 1.02-2.64) and with diabetes 2.06 (95% confidence interval 1.27-3.34). It was not possible to distinguish among additive and multiplicative models of the joint association of radiation dose and various non-radiation-related exposures (age at menarche, full-term pregnancy, female hormone preparations) identified in this analysis. CONCLUSIONS:Nonradiation risk factors for breast cancer among Japanese atomic bomb survivors were consistent with those identified among other populations of women, although the prevalence of common risk factors was low. Reproductive factors and hormone use appear to act independently of radiation exposure on the risk of breast cancer among this population.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Goodman MT,Cologne JB,Moriwaki H,Vaeth M,Mabuchi Kdoi
10.1006/pmed.1996.9979subject
Has Abstractpub_date
1997-01-01 00:00:00pages
144-53issue
1eissn
0091-7435issn
1096-0260pii
S0091-7435(96)99979-Xjournal_volume
26pub_type
杂志文章abstract:BACKGROUND:Since survival of patients with melanoma is strongly correlated with the Breslow tumor thickness of the primary lesion, factors that influence stage at diagnosis and delay in diagnosis are considered to be crucial. To test the relationship between tumor thickness and some social and clinical variables (inclu...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2002.1067
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To report on the contribution walking makes to total weekly physical activity and the relationship between the volume and intensity of walking and leanness in a representative sample of the Northern Ireland population. METHOD:4563 adults participated in this cross-sectional survey of physical activity behavi...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2011.12.008
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Neonatal abstinence syndrome (NAS) occurs following prenatal opioid exposure. It is characterized by signs and symptoms indicating central nervous system hyperirritability and autonomic nervous system, gastrointestinal tract, and respiratory system dysfunction. OBJECTIVE:This article: (1) briefly reviews NA...
journal_title:Preventive medicine
pub_type: 历史文章,杂志文章
doi:10.1016/j.ypmed.2015.07.017
更新日期:2015-11-01 00:00:00
abstract::A prospective analysis was used to test whether respiratory impairment or the presence of respiratory symptoms predicts 5-year cigarette smoking cessation in a sample of 1,118 U.S. white, male, underground coal miners. Miners were examined in 1977 and re-examined in 1982 by NIOSH, and all miners with test abnormalitie...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(85)90033-7
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:The joint effect of family history of acute myocardial infarction (AMI) and selected adult life risk factors on the risk of the disease is not clear. METHODS:We used the combined data set from three Italian case-control studies including 1737 cases of incident, nonfatal AMI and 2317 hospital controls, aged ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2003.11.019
更新日期:2004-04-01 00:00:00
abstract::Poverty has consistently been linked to poor mental health and risky health behaviors, yet few studies evaluate the effectiveness of programs and policies to address these outcomes by targeting poverty itself. We test the hypothesis that the earned income tax credit (EITC)-the largest U.S. poverty alleviation program-...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106223
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Timing of obesity development during childhood and adolescence is unclear, hindering preventive strategies. The primary aim of the present study was to quantify the incidence of overweight and obesity throughout childhood and adolescence in a large contemporary cohort of English children (the Avon L...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2011.02.014
更新日期:2011-05-01 00:00:00
abstract::This study examined whether availability and use of different types of school-based health services (SBHS) during adolescence were associated with educational attainment in adulthood. Data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) were analyzed in 2018 to assess relationships betw...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.02.019
更新日期:2019-04-01 00:00:00
abstract::While several cross-sectional studies have shown that self-efficacy, self-esteem and optimism are associated with the use of routine health check-ups, little is known about this relationship based on longitudinal studies. Consequently, the purpose of this study was to examine whether these factors are associated with ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.08.030
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To determine the effect of age and study period on coronary heart disease (CHD) risk attributable to cardiovascular risk factors. METHODS:A cohort of cardiovascular disease (CVD)-free randomly participants from Girona (Spain) aged 35-74 years recruited in 1995 and 2000 and followed for an average of 6.9 year...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2010.03.012
更新日期:2010-07-01 00:00:00
abstract::Tobacco-related health disparities disproportionately affect smokers with major depression (MD). Although tobacco simulation models have been applied to general populations, to date they have not considered populations with a comorbid mental health condition. We developed and calibrated a simulation model of smoking a...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106241
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Previous reports have indicated that coffee drinking is associated with an unhealthy lifestyle, compared with tea drinking, which may confound the effect in relation to coronary risk factors. METHODS:In a population sample of 2,400 25- to 64-year-old men and women, associations of lifestyle factors with cof...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1994.1052
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Lifestyle factors, sometimes associated with physical health and mortality, have also been known to be associated with mental health status. This study seeks to correlate behavioral lifestyles with major components of mental health among Japanese factory workers. METHOD:We administered the 28-item version o...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1994.1014
更新日期:1994-01-01 00:00:00
abstract::Children and adolescents recently have become a group targeted for health promotion efforts. It is argued that early behavioral intervention will alter patterns of behavior that might place young people at increased risk for chronic diseases later in life. The Minnesota Heart Health Program is a longitudinal, communit...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(85)90064-7
更新日期:1985-05-01 00:00:00
abstract::We present a redesign of medical test results by placing the information of blood samples in the context of the patient's personal clinical data. We predict that implementing personalized data in the treatment of patients will promote engagement in the treatment, motivate patients to take responsibility and lead to gr...
journal_title:Preventive medicine
pub_type: 信件
doi:10.1016/j.ypmed.2014.08.008
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Nutrition interventions targeted to individuals are unlikely to significantly shift US dietary patterns as a whole. Environmental and policy interventions are more promising for shifting these patterns. We review interventions that influenced the environment through food availability, access, pricing, or inf...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2004.04.002
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:The effects and constancy of a worksite physical exercise intervention were examined in relation to the physical fitness, perceived health status, and work ability of female service workers during periods of 1 and 5 years. METHODS:The subjects comprised female home care workers divided into an intervention g...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章
doi:10.1006/pmed.2001.0837
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:The study examined the association of neighborhood walkability to multiple activity-related outcomes and BMI among adolescents and evaluated socioeconomic status as an effect modifier. METHOD:Cross-sectional study, with adolescents recruited from neighborhoods that met criteria for a 2 × 2 matrix defined ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.02.009
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Cigarette smoking is the leading preventable cause of death and disease in the United States. Sexual minorities (lesbians, gay men, and bisexuals), smoke at higher rates than the general population. However, little else is known about sexual minority smokers. Furthermore, the sexual minority population is div...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.11.026
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Several international guidelines have recommended the involvement of general practitioners (GPs) in screening programs, but current evidence suggests this is very difficult. We implemented a survey to understand the attitudes, knowledge, and practices regarding colorectal cancer screening of GPs in the Lazio...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2004.11.010
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:This paper examines the prevalence of household and car smoking restrictions, factors associated with these restrictions, and children's exposure to secondhand smoke in homes with varying levels of household smoking restrictions in rural Native American and White families. METHODS:In-person interviews were ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2002.1091
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Neighborhood built environments (BE) include combinations of co-existing stimuli influencing physical activity (PA). Dealing with numerous environmental variables and complexity presents a significant challenge. The current analysis explored whether a range of reported BE features associated with adults' phy...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2011.02.020
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:This study examined the joint influence of work- and household-related variables on smoking behavior among a population representative sample of blue-collar workers with live-in partners. METHODS:The study used data on 1389 blue-collar workers from the Tobacco Use Supplement to the United States Current Popu...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.12.005
更新日期:2013-02-01 00:00:00
abstract::In this commentary, we reflect on the growing opioid overdose epidemic and propose that chronic pain patients prescribed opioids are contributing to growing mortality rates. We advocate for expanding naloxone access and overdose prevention training, which has historically been directed when available to injection drug...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2015.05.016
更新日期:2015-11-01 00:00:00
abstract::Providing smoking cessation treatment with annual low dose CT (LDCT) screening offers an opportunity to reduce smoking-related morbidity and mortality. However, the optimal approach for delivering cessation interventions in the LDCT screening context is unknown. We searched for randomized controlled trials and observa...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.02.016
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this paper is to make a case for Comprehensive School Physical Activity Program (CSPAP) to be the organizational framework for providing physical activity opportunities for children that is most likely to result in physical literacy. METHOD:Beginning in 2010, the authors used multiple search e...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.06.007
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the relationship between walking or cycling to work and prevalence of metabolic syndrome (MetS) and its components. METHODS:Cross-sectional analysis of 6401 randomly selected individuals (3297 men and 3104 women) aged 20-74 years, who participated in the National Multice...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2010.09.003
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:The present study sought to examine the independent associations of parental education and physical activity (PA) with children's PA across Europe. METHODS:A total of 7214 children (10-12 years) were recruited from a school-based cross-sectional survey during 2010 in seven European countries. Weight and heig...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.07.011
更新日期:2012-10-01 00:00:00
abstract::Prior research and systematic reviews have examined strategies related to weight management, less is known about lifestyle and behavioral counseling interventions optimally suited for implementation in primary care practices generally, and among racial and ethnic patient populations. Primary care practitioners may fin...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2017.03.020
更新日期:2017-07-01 00:00:00
abstract::The objective of this paper is to estimate the impact of county-level public transit usage on obesity prevalence in the United States and assess the potential for public transit usage as an intervention for obesity. This study adopts an instrumental regression approach to implicitly control for potential selection bia...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.03.010
更新日期:2017-06-01 00:00:00