Short communication: a new technique in immunosuppression of Syrian hamsters xenografted with human tumors.

abstract：:Eighty-eight patients with histologically confirmed colon cancer and two control groups individually matched by age, sex and place of residence, were interviewed about demographic, biosocial and medical variables. The use of laxatives, past history of large bowel disease and coffee consumption for 20 or more years wer...

journal_title：Neoplasma

authors： Vlajinac H,Jarebinski M,Adanja B

更新日期：1987-01-01 00:00:00

abstract：:We investigate the clinical characteristics, prognosis and treatment of relapsed and refractory Hodgkin's lymphoma. Twenty patients with relapsed and refractory Hodgkin lymphoma were treated by chemotherapy or autologous stem cell transplantation in our hospital from April 2006 to August 2012. The retrospective analys...

journal_title：Neoplasma

authors： Yang HL,Zhang YZ,Jiang YZ,Wang XF,Cao Z

更新日期：2017-01-01 00:00:00

abstract：:During the last 30 years the trends in cancer mortality in Europe significantly changed. In 1970 the male and female cancer mortality (all ages) was higher in the Western Europe than in the "socialist" Central and Eastern Europe. After 1970 in most Western countries decrease or no change of male premature (0-64 years)...

journal_title：Neoplasma

authors： Ginter E

更新日期：2000-01-01 00:00:00

abstract：:The oral cavity is continually exposed to various traumas due to the effect of thermal, mechanical and chemical stimuli, which when accompanied by inflammatory states may promote the growth of neoplastic changes. Numerous studies have revealed a correlation between the expression of p53 and Bcl-2 proteins and the prog...

journal_title：Neoplasma

authors： Sulkowska M,Famulski W,Chyczewski L,Sulkowski S

更新日期：2001-01-01 00:00:00

abstract：:The aim of this study was a contemporaneous measurement and a mutual comparison of plasma cells proliferative activity and grade of apoptosis in patients with monoclonal gammopathy of undetermined significance (MGUS) and various phases of MM i.e. smoldering (SMM), stable/plateau and active (progression/relapse) forms ...

journal_title：Neoplasma

authors： Scudla V,Ordeltova M,Bacovsky J,Vytrasova M,Sumna E,Martinek A,Horak P

更新日期：2003-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer mortality worldwide. Although advances have made in treatment of HCC, the overall survival rate remains low and the molecular pathogenesis of HCC is still poorly understood. The purpose of this study was to explore the molecular pathogenesis of HCC. ...

journal_title：Neoplasma

authors： Huang H,Wang X,Wang C,Zhuo L,Luo S,Han S

更新日期：2017-01-01 00:00:00

abstract：:The work is aimed at the occurrence of secondary malignancies after therapy for primary testicular tumors. The target of the work was determination of the number and type of secondary tumors, their effect on the survival and comparison of relative risk of the origination of secondary tumors depending on particular tre...

journal_title：Neoplasma

authors： Siffnerova H,Kralova D

更新日期：2007-01-01 00:00:00

abstract：:Puerarin has recently been demonstrated to play anti-cancer roles in a series of human cancers, including non-small cell lung cancer (NSCLC), possibly through regulation of cancer-related microRNAs (miRNAs). The purpose of the present study was to further investigate the detailed role and underlying mechanism of puera...

journal_title：Neoplasma

authors： Huang SR,Jin SS,Xu B,Wang RP

更新日期：2020-11-01 00:00:00

abstract：:Regional lymph nodes in 80 cases of gastric and 70 cases of breast cancer have been examined and the reactive types have been correlated to the survival periods of the patients. In both groups of patients, a prognostically favorable sign was the detection of lymphocytic predominance combined with sinus histiocytosis, ...

journal_title：Neoplasma

authors： Riegrová D,Jansa P

更新日期：1982-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the most common primary malignancy of the liver. The chemotherapeutic drug cisplatin is widely used for advanced liver cancer. However, the development of cisplatin resistance in cancer cells, which is related with the decreased cellular susceptibility to apoptosis, results in a major limit...

journal_title：Neoplasma

authors： Zhang B,Cao K,Liu Z,Shan W,Wen Q,Wang R

更新日期：2019-05-11 00:00:00

abstract：:A capture monoclonal antibody-based assay has been established for detecting the p24 core protein and the gp51 envelope glycoprotein of bovine leukemia virus (BLV). This assay is rapid, highly sensitive and specific. Viral antigens in test samples were identified using mouse monoclonal antibody-coated or microtiter pl...

journal_title：Neoplasma

authors： Bán J,Altanerová V,Orlík O,Altaner C

更新日期：1991-01-01 00:00:00

abstract：:Due to problems with identification and an incomplete understanding on the gastrointestinal stromal tumors (GIST) before 2001, there has been a lack of comprehensive long-term population-based studies on GIST epidemiology at present date. We used data from the online registry of Czech and Slovak GIST patients (http://...

journal_title：Neoplasma

authors： Brabec P,Sufliarsky J,Linke Z,Plank L,Mrhalova M,Pavlik T,Klimes D,Gregor J

更新日期：2009-01-01 00:00:00

abstract：:The antitumor activity of phthalmustine (Neoplasma, 41, 1994, 35) has been evaluated in murine Ehrlich ascites carcinoma (EAC) and sarcoma-180 (S-180). The hematological changes associated with the application of phthalmustine were also evaluated in tumor bearing as well as in normal male Swiss mice. The results indic...

journal_title：Neoplasma

authors： Bhattacharya S,Ghosh M,Sadhu U,Dutta S,Sanyal U

更新日期：1996-01-01 00:00:00

abstract：:16 colon cancer patients in the second clinical stage (according to the TNM classification), aged 34 to 71 years were studied before and 14 days after radical surgery. The in vitro cell-mediated immunity was evaluated using the rosette-forming test and blastogenic reactivity of blood lymphocytes to PHA. The percentage...

journal_title：Neoplasma

authors： Markova R,Argirova R,Boeva M

更新日期：1980-01-01 00:00:00

abstract：:The macrocyclic Cu(II)-tetraanhydroaminobenzaldehyde complex Cu(TAAB)C12 induces various cytotoxic effects in the dependence on a cell line, concentration and time of exposition. The highest complex concentration of 914 nmol/l induces degeneration of certain part of the HeLa cells population after 24 hours of cultivat...

journal_title：Neoplasma

authors： Jantová S,Duracková Z,Novotný L,Urbancíková M,Dovinová I,Labuda J,Wsolová L

更新日期：1998-01-01 00:00:00

abstract：:Multiple myeloma (MM) is a hematological malignancy caused by clonal proliferation of malignant plasma cells (PC). The aim of the work is to determine prognostic significance of morphological subtypes of PC in relation to overall treatment response, long-term survival and other conventional prognostic parameters. One ...

journal_title：Neoplasma

authors： Al-Sahmani M,Trnavska I,Sevcikova S,Antosova M,Antosova L,Kissova J,Adam Z,Pour L,Nemec P,Greslikova H,Krejci M,Zahradova L,Bulikova A,Penka M,Hajek R

更新日期：2011-01-01 00:00:00

abstract：:MSH-PE38KDEL is a chimeric molecule composed of MSH, and fused to a truncated mutant form of Pseudomonas exotoxin (PE38KDEL). Our study aims to evaluate the specific cytotoxicity of recombinant immunotoxin MSH-PE38KDEL on melanoma cells A875 and B16 in vitro, as well as its inhibition of metastatic melanoma in vivo. M...

journal_title：Neoplasma

authors： Hui Q,Ma J,Song J,Liu Z,Ren H,Jiang W,Wang Y,Xu Y,Guo D,Zhang X,Lu S

更新日期：2014-01-01 00:00:00

abstract：:Relation between the electronic structure of aromatic compounds and their carcinogenic activity has been correlated. Hypotheses of K, L regions have been employed. Possibilities of better theoretical description of carcinogenic activity have been examined by including the effect of medium and by using a more exact qua...

journal_title：Neoplasma

authors： Miertus S

更新日期：1979-01-01 00:00:00

abstract：:Molecular genetic studies have revealed mutations in a number of oncogenes and tumor suppressor genes in lung cancer. The bcl-2 gene product (bcl-2 protein) is implicated in oncogenesis by its ability to prolong cell death through the inhibition of apoptosis. We investigated expression of bcl-2 in 84 resected human no...

journal_title：Neoplasma

authors： Laudanski J,Chyczewski L,Niklińska WE,Kretowska M,Furman M,Sawicki B,Nikliński J

更新日期：1999-01-01 00:00:00

abstract：:PMP22 is recently recognized as a key player in a variety of prevalent cancers. In this study, we sought to explore the correlation of peripheral myelin protein 22 (PMP22) expression with cell proliferation, invasion and apoptosis in lung cancer cell line. miR29 was transfected into Anip973 lung adenocarcinoma cell li...

journal_title：Neoplasma

authors： Qu H,Zhu M,Tao Y,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：:A comparative study has been performed on the relationship between vitamin E and immunofunction in normal and malignant condition in human and murine systems. Further, the effects of supplemental vitamin E on tumor take, host survival and tumor growth have been studied in a transplantable lymphoma in mice. Vitamin E w...

journal_title：Neoplasma

authors： Dasgupta J,Sanyal U,Das S

更新日期：1993-01-01 00:00:00

abstract：:Mammalian target of rapamycin (mTOR) has two subtypes, i.e., mTORC1 and mTORC2, which contain the Raptor and Rictor core molecules, respectively. The effect of Raptor and Rictor on hypoxia inducible factor (HIF)-1α, HIF-2α, and vascular endothelial growth factor (VEGF) in colorectal cancer (CRC) is unclear. In this wo...

journal_title：Neoplasma

authors： Wen FF,Li XY,Li YY,He S,Xu XY,Liu YH,Liu L,Wu SH

更新日期：2020-05-01 00:00:00

abstract：:Positron emission tomography (PET) is a new diagnostic method recently widely used in oncology. It is applied to distinguish benign and malign tumors, to diagnose relaps or posttherapeutic changes. PET is also complementary method to the standard used methods such as CT or NMR. Now it is used even as the predict facto...

journal_title：Neoplasma

authors： Dolezelová H,Slampa P

更新日期：2007-01-01 00:00:00

abstract：:Genomic, epigenetic and expression alterations of WW domain containing oxidoreductase (WWOX) have been implicated in multiple tumor types. The current study was designed to examine the expression of WWOX in tumor tissues of human bladder transitional cell carcinoma (BTCC) and the influence of cigarette smoke extract (...

journal_title：Neoplasma

authors： Yang W,Cui S,Ma J,Lu Q,Kong C,Liu T,Sun Z

更新日期：2012-01-01 00:00:00

abstract：:The clinical significance of thymosin β4 (Tβ4) expression in bladder transitional cell carcinoma (BTCC) remains unclear. The present study assessed the relationship between the expression of Tβ4 protein and the clinicopathological features, as well as the prognosis of bladder cancer patients. Tβ4 protein expression in...

journal_title：Neoplasma

authors： Wang ZY,Zhang W,Yang JJ,Song DK,Wei JX,Gao S

更新日期：2016-01-01 00:00:00

abstract：:The effects of the specific active cancer immunotherapy utilizing autologous tumor tissue particles polymerized with ethylchlorformiate on the immune system of the host were evaluated in DBA/2 mice bearing a malignant mast cell tumor, mastocytoma (P-815 X 2), with the special emphasis placed on the morphologic changes...

journal_title：Neoplasma

authors： Syrjänen KJ,Soimakallio S

更新日期：1980-01-01 00:00:00

abstract：:In a group of 11,153 autopsied subjects a higher number of cholecystectomies was found in both sexes in individuals with large intestine tumors as compared with the rest of the autopsied persons without tumors (p less than 0.001). The results confirmed the hypothesis that cholecystectomy is a supporting factor in the ...

journal_title：Neoplasma

authors： Hladík V,Nozicka Z,Maslowská H

更新日期：1987-01-01 00:00:00

abstract：:Forty-four cases of well documented progressive radiation myelopathy of thoracic spinal cord were analyzed in terms of the new DFT conception (Dose-Fraction-Time). The DFT conception is a new radiobiological cell tissue kinetic model comprising explicitly repopulation. The conception has been previously tested against...

journal_title：Neoplasma

authors： Vodvárka P,Kozubek S

更新日期：1986-01-01 00:00:00

abstract：:The plasminogen activator (PA) production and the capacity to inhibit embryonic neural retina (NR) cell aggregation by human normal and neoplastic cell lines have been studied. The PA production was detected by both iodinated fibrin and casein lysis assays, and by changes in cell morphology at the presence of activate...

journal_title：Neoplasma

authors： Phan Thu A,Popovic M

更新日期：1979-01-01 00:00:00

abstract：:To date, epidemiological studies have assessed the association between Toll-like receptor 2 (TLR2) gene polymorphisms and cancer risk. However, the results of these studies remain controversial. We aimed to examine the associations between three SNPs (Delta22, rs3804099 and rs3804100) of TLR2 gene and cancer risk by c...

journal_title：Neoplasma

authors： Wang X,Li J,Xie W,Zhang W,Chang Y

更新日期：2013-01-01 00:00:00