Abstract：
:The antitumor activity of phthalmustine (Neoplasma, 41, 1994, 35) has been evaluated in murine Ehrlich ascites carcinoma (EAC) and sarcoma-180 (S-180). The hematological changes associated with the application of phthalmustine were also evaluated in tumor bearing as well as in normal male Swiss mice. The results indicate that phthalmustine induces marked inhibition of tumor growth and substantially prolongs host survival having curative effect while it does not adversely affect hematopoiesis at the optimum dose tested. No toxic symptoms were noted with respect to external appearance, body weight changes and behavioral pattern.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Bhattacharya S,Ghosh M,Sadhu U,Dutta S,Sanyal Usubject
Has Abstractpub_date
1996-01-01 00:00:00pages
209-13issue
3eissn
0028-2685issn
1338-4317journal_volume
43pub_type
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