Calculations of theoretical indices of carcinogenic activity including the effect of medium.

Abstract:

:Relation between the electronic structure of aromatic compounds and their carcinogenic activity has been correlated. Hypotheses of K, L regions have been employed. Possibilities of better theoretical description of carcinogenic activity have been examined by including the effect of medium and by using a more exact quantum--chemical method. Theoretical carcinogenic activity of some compounds so far experimentally not tested has been estimated.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Miertus S

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

133-8

issue

2

eissn

0028-2685

issn

1338-4317

journal_volume

26

pub_type

杂志文章
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    abstract::The paper deals with some results of work done in the USSR to establish maximal allowable doses (MAC) for the carcinogenic hydrocarbon benza(a)pyrene in human environment. At the same time it is a brief review of some discussions on this item which took place in USSR and on the international level. ...

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    doi:

    authors: Shabad LM

    更新日期:1975-01-01 00:00:00

  • Overexpression of AEG-1 in renal cell carcinoma and its correlation with tumor nuclear grade and progression.

    abstract:UNLABELLED:The study was aimed at detecting the expression of a newly found oncogene, astrocyte elevated gene-1 (AEG-1), in renal cell carcinoma (RCC) and its correlation with histopathologic features and the survival of patients. Real-time reverse transcription-PCR and Western blot showed markedly higher expression of...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2010_06_522

    authors: Chen W,Ke Z,Shi H,Yang S,Wang L

    更新日期:2010-01-01 00:00:00

  • Diagnosis of bovine leukosis virus infection by solid phase radioimmunoassay for virus antibody.

    abstract::Solid phase radioimmunoassay for detection of anti-BLV antibodies in sera of infected animals is described. Viral antigens bound to surface of polystyrene are able selectively adsorb the antibodies from serum. Detection of bound antibodies quantitatively was done by 125I-labeled protein A from Staphylococcus aureus. T...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Zajac V,Altaner C

    更新日期:1981-01-01 00:00:00

  • Invasive thymoma (a case report).

    abstract::A 10-year old Nigerian boy was admitted to hospital with a history of swelling in the neck, change of voice, dysphagia and dyspnoea of 2 weeks duration. He died on the 2nd day of admission. Autopsy revealed a thymoma infiltrating the thyroid, trachea and neck muscles and transforming the tracheal lumen into a slit lik...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Suseelan AV,Ikerionwu SE,Ojukwu JO

    更新日期:1979-01-01 00:00:00

  • Sensitivity of TSTA and species-specific cell membrane antigens of tumor cells to glutaraldehyde treatment.

    abstract::In vivo immunogenicity and in vitro species-specific membrane antigens in tumor cells treated or untreated with glutaraldehyde (GA) were studied. Two different syngeneic Syrian hamster transplantable tumor cell lines (spontaneous liver cancer and SV40-induced sarcoma) not only lost immunogenicity after GA treatment bu...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Kluchareva TE,Matveeva VA,Deichman GI

    更新日期:1978-01-01 00:00:00

  • Clonal evolution of karyotype in blastic phase of CML.

    abstract::A patient with chronic myelocytic leukemia (CML) had a Philadelphia chromosome--Ph1(t(9q +; 22q--)) in all evaluated bone marrow cells at the time of diagnosis. After 29 months of intermittent therapy (chemotherapy and immunotherapy) and 2 months before clinical signs of blastic phase developed, three additional cell ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Izakovic V,Horák I,Krizan P

    更新日期:1982-01-01 00:00:00

  • The results of allogeneic transplants in patients with malignant lymphoma-a retrospective analysis of data from the Czech National Registry.

    abstract::We processed data of 79 patients (pts) with malignant lymphoma from the National Registry of haematopoietic stem cell transplants conducted between 1997 and 2006. The haematopoietic stem cell donor in 48 pts was an HLA matched relative, and in 30 pts an unrelated volunteer. Sixty (77%) pts were transplanted with reduc...

    journal_title:Neoplasma

    pub_type: 杂志文章,多中心研究

    doi:10.4149/neo_2009_01_76

    authors: Valkova V,Benesova K,Vitek A,Faber E,Mayer J,Zak P,Trneny M

    更新日期:2009-01-01 00:00:00

  • Survival rate of colon and rectum cancer in Iran: A systematic review and meta-analysis.

    abstract::Colorectal cancer is one of the deadliest cancers worldwide. Effective screening, surveillance and prevention can decrease its incidence, mortality and burden. This meta-analysis aims to provide a pooled estimation of 5-year survival rate for colorectal cancer based on topography codes and treatment in Iranian populat...

    journal_title:Neoplasma

    pub_type: 杂志文章,meta分析

    doi:10.4149/neo_2019_190131N92

    authors: Panahi MH,Panahi H,Mahdavi Hezaveh A,Mansournia MA,Bidhendi Yarandi R

    更新日期:2019-11-01 00:00:00

  • D-dimer, plasminogen activator inhibitor-1, prothrombin fragments and protein C - role in prothrombotic state of colorectal cancer.

    abstract::The relationship between malignant tumors and blood coagulation disorders is generally well known. The authors studied blood coagulation in patients with colorectal cancer and evaluated some prothrombotic markers. The authors analyzed by latex-aglutination method, ProC Global test, Asserachrom PAI-1 test and Enzygnost...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2011_03_235

    authors: Mytnik M,Stasko J

    更新日期:2011-01-01 00:00:00

  • Vitamin E--its status and role in leukemia and lymphoma.

    abstract::A comparative study has been performed on the relationship between vitamin E and immunofunction in normal and malignant condition in human and murine systems. Further, the effects of supplemental vitamin E on tumor take, host survival and tumor growth have been studied in a transplantable lymphoma in mice. Vitamin E w...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Dasgupta J,Sanyal U,Das S

    更新日期:1993-01-01 00:00:00

  • Nonmelanoma skin cancers and risk of subsequent malignancies: a cancer registry-based study in Bulgaria.

    abstract::Analysis of new primary tumors following nonmelanoma skin cancers (NMSC) has a public health and risk assessment interest, as well as potential implications for etiologic inference. The aim of this study is to evaluate the risk of the second primary tumors occurrence after NMSC development. A cohort of 2620 cases (133...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Troyanova P,Danon S,Ivanova T

    更新日期:2002-01-01 00:00:00

  • Phosphorylation of acyclic nucleotide analogs HPMPA and PMEA in L1210 mouse leukemia cell extracts.

    abstract::Acyclic nucleotide analogs (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine (HPMPA) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA) were phosphorylated in the presence of ribonucleoside 5'-triphosphates by the crude extract from mouse leukemia cells L1210 affording the respective mono- and diphosphoryl derivatives. T...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Merta A,Veselý J,Votruba I,Rosenberg I,Holý A

    更新日期:1990-01-01 00:00:00

  • The potential roles of vesicle-enclosed miRNAs in communication between macrophages and cancer cells in tumor microenvironment.

    abstract::Functional microRNA (miRNA) molecules are transported in extracellular vesicles among tumor cells and cells of the immune system. Macrophages as integral components of tumor microenvironment are known as potential contributors to tumor growth and progression. We searched for studies which could provide a direct link b...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2017_311

    authors: Korabecna M,Koutova L,Tesarova P

    更新日期:2017-01-01 00:00:00

  • CEA-like antigens in different histologic types of human lung carcinoma.

    abstract::Comparative studies on the presence and immunological reactivity of CEA and CEA-like antigens in lung and digestive tract cancers were performed. Specific goat and rabbit anti-CEA immune sera were used. Immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cro...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Harłozińska A,Albert W,Rogalski E,Richter R,Albert Z

    更新日期:1979-01-01 00:00:00

  • Clastogenic effects of N-nitrosodimethylamine and dinitrosoglycolurile in murine bone marrow cells and cow lymphocytes.

    abstract::The clastogenic effects of N-nitrosodimethylamine (N-DMA) and dinitrosoglycolurile (DNSGU) were studied in the bone marrow of mice and in peripheral blood lymphocytes of cows. None of the tested compounds showed significant enhancement of chromosome aberrations at doses 1/2 LD50 and 1/10 LD50 in murine bone marrow cel...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Siviková K

    更新日期:1994-01-01 00:00:00

  • Detection of specific immunoreactivity by LAI assay in patients with malignant melanoma of uveal tissue.

    abstract::To monitor the specific antitumor immunity to patients with malignant melanoma of the uveal tissue, use was made of the 20-hr modification of the leukocyte adherence inhibition (LAI) test. Simultaneously, changes in the proportionally of T (total and active) and B lymphocytes in peripheral blood were followed in the s...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Kalafut F,Cernák A,Pham Manh Hung

    更新日期:1979-01-01 00:00:00

  • Stage of bladder cancer in Central Europe - Polish perspective.

    abstract::Mortality rate from bladder cancer in Europe is the highest in its Central Region. This study is an attempt to find underlying factors by proper characterisation of large cohort of Polish patients with bladder cancer.This is a multicentre study enrolling 1360 consecutive patients diagnosed with primary urothelial carc...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2016_420

    authors: Poletajew S,Biernacki R,Buraczynski P,Chojnacki J,Czarniecki S,Gajewska D,Pohaba T,Sondka J,Skrzypczyk M,Suchojad T,Wojtkowiak D,Zaforemski B,Zapala L,Zemla A,Radziszewski P

    更新日期:2016-01-01 00:00:00

  • Suppression of peripheral myelin protein 22 (PMP22) expression by miR29 inhibits the progression of lung cancer.

    abstract::PMP22 is recently recognized as a key player in a variety of prevalent cancers. In this study, we sought to explore the correlation of peripheral myelin protein 22 (PMP22) expression with cell proliferation, invasion and apoptosis in lung cancer cell line. miR29 was transfected into Anip973 lung adenocarcinoma cell li...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2015_107

    authors: Qu H,Zhu M,Tao Y,Zhao Y

    更新日期:2015-01-01 00:00:00

  • The impact of positron emission tomography in the radiotherapy treatment planning. Minireview.

    abstract::Positron emission tomography (PET) is a new diagnostic method recently widely used in oncology. It is applied to distinguish benign and malign tumors, to diagnose relaps or posttherapeutic changes. PET is also complementary method to the standard used methods such as CT or NMR. Now it is used even as the predict facto...

    journal_title:Neoplasma

    pub_type: 杂志文章,评审

    doi:

    authors: Dolezelová H,Slampa P

    更新日期:2007-01-01 00:00:00

  • Cigarette smoking extract causes hypermethylation and inactivation of WWOX gene in T-24 human bladder cancer cells.

    abstract::Genomic, epigenetic and expression alterations of WW domain containing oxidoreductase (WWOX) have been implicated in multiple tumor types. The current study was designed to examine the expression of WWOX in tumor tissues of human bladder transitional cell carcinoma (BTCC) and the influence of cigarette smoke extract (...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2012_028

    authors: Yang W,Cui S,Ma J,Lu Q,Kong C,Liu T,Sun Z

    更新日期:2012-01-01 00:00:00

  • Mitochondrial ATPase of Zajdela hepatoma. V. Mitochondria of Zajdela hepatoma contain membrane sectors of ATPase complex unassociated with F1.

    abstract::Relative content of membrane sectors of ATPase complex in rat liver and Zajdela hepatoma mitochondria and the ability of mitochondrial membrane of the two sources to bind isolated soluble (F1) ATPase were examined. Approximately equal concentrations of oligomycin were required for 50% inhibition of ATPase activity in ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Kuzela S,Kolarov J,Krempaský V,Luciaková K,Ujházy V

    更新日期:1978-01-01 00:00:00

  • Preliminary results with the new cytostatic Penberol in ovarian carcinoma.

    abstract::The authors present results of a preliminary study on the efficiency of the preparation Penberol [VUFB Prague (cis-beta-4-pentoxy-benzoyl-beta-bromoacrylic acid) CHECO protocol number 4] in the ovarian carcinoma of the stage III and IV (FIGO) in which the drug was used after the failure of the first choice chemotherap...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Novotná J,Andrysek O

    更新日期:1980-01-01 00:00:00

  • MicroRNA-101 regulates autophagy, proliferation and apoptosis via targeting EZH2 in laryngeal squamous cell carcinoma.

    abstract::Laryngeal carcinoma is the second commonest head and neck carcinoma globally. MicroRNA-101 (miR-101) has been reported as a tumor suppressor in multiple malignancies including laryngeal squamous cell carcinoma (LSCC). However, the roles and molecular mechanisms of miR-101 in the development of LSCC have not been fully...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_180811N611

    authors: Chen L,Jia J,Zang Y,Li J,Wan B

    更新日期:2019-07-23 00:00:00

  • Distribution of normal T lymphocytes in tumor-bearing rats.

    abstract::Changes in distribution properties of T lymphocytes from lymphoid organs of normal rats 3H-uridine labeled in vitro and i. v. injected to tumor-bearing recipients were studied at different stages of tumor growth and rejection. Comparisons were made with T cell migration from normal donors to syngeneic recipients. A te...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Klobusická M,Koníková E

    更新日期:1982-01-01 00:00:00

  • Studies on T and B lymphocytes in rats bearing methylcholanthrene-induced tumor.

    abstract::The authors have studied the influence of primary, methylcholanthrene-induced tumor on T and B lymphocytes of spleen, thymus, draining lymph nodes and peripheral blood of rats. Differences in weight of tumors were found to correlate with changes in proportionality of T and B lymphocytes of followed organs. Small tumor...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Klobusická M,Kalafut F,Novotná L

    更新日期:1978-01-01 00:00:00

  • Combined radioprotective effect of Broncho-Vaxom and WR-2721 on hemopoiesis and circulating blood cells.

    abstract::Possibilities of combined radioprotection, using preirradiation WR-2721 administration and post- or preirradiation Broncho-Vaxom administration in lethally whole-body gamma-irradiated mice were investigated. Combined modality treatments were more effective than individual treatments alone. The ameliorative influence o...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Macková NO,Fedorocko P

    更新日期:1995-01-01 00:00:00

  • Circulating immune complexes in patients with lymphomas and leukemias.

    abstract::Immune complexes (IC) were examined in the sera of 100 patients with histologically confirmed non-Hodgkin's lymphoma (NHL) and 80 leukemic patients by the EA-rosette forming cell inhibition assay. Sera from 55 healthy controls were also tested for the presence of IC. Using 9% rosette inhibition as a base-line, IC were...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Patel GV,Gopal R,Nadkarni JJ

    更新日期:1984-01-01 00:00:00

  • Integrated network analysis to identify the key genes, transcription factors, and microRNAs involved in hepatocellular carcinoma.

    abstract::HCC (hepatocellular carcinoma), which can be induced by cirrhosis and viral hepatitis infection, is the most frequent form of liver cancer. This study is performed to investigate the mechanisms of HCC. GSE57957 was obtained from Gene Expression Omnibus database, including 39 HCC samples and 39 adjacent non-tumorous sa...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_161215N642

    authors: Shi SQ,Ke JJ,Xu QS,Wu WQ,Wan YY

    更新日期:2018-01-01 00:00:00

  • Flotillin 1 is differentially expressed in human epithelial ovarian tumors.

    abstract::Although Flotillin 1 (FLOT1) is highly expressed in various human cancers, its relationship with ovarian cancer (OC) remains unknown. This study determines FLOT1 expression in human ovarian tumors and examines its effect on OC   cell proliferation. FLOT1 protein expression was assessed in a tissue microarray by immuno...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_170714N483

    authors: Li J,Zuo X,Shi J,Zhang J,Duan X,Xu G

    更新日期:2018-01-01 00:00:00

  • Stepwise transition of aggregate structure of high-molecular-weight avian myeloblastosis virus RNA. Mode of releasing of associated 4S RNA.

    abstract::Mode of releasing of associated 4S RNA species was studied during a controlled transition of aggregate structure of high-molecular-weight AMV-RNA. It has been found that associated 4S RNA constitutes 2.5% of 60S AMV-RNA complex. Approximately 60% of associated 4S RNA is successively released during treatment of viral ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Trávnícek M,Ríman J

    更新日期:1976-01-01 00:00:00