Abstract：
:As studies have pointed out, severity scores are imperfect at predicting individual clinical chance of survival. The clinical condition and pathophysiological status of these patients in the Intensive Care Unit might differ from or be more complicated than most predictive models account for. In addition, as the pathophysiological status changes over time, the likelihood of survival day by day will vary. Actually, it would decrease over time and a single prediction value cannot address this truth. Clearly, alternative models and refinements are warranted. In this study, we used discrete-time-event models with the changes of clinical variables, including blood cell counts, to predict daily probability of mortality in individual patients from day 3 to day 28 post Intensive Care Unit admission. Both models we built exhibited good discrimination in the training (overall area under ROC curve: 0.80 and 0.79, respectively) and validation cohorts (overall area under ROC curve: 0.78 and 0.76, respectively) to predict daily ICU mortality. The paper describes the methodology, the development process and the content of the models, and discusses the possibility of them to serve as the foundation of a new bedside advisory or alarm system.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Huang YC,Chang KY,Lin SP,Chen K,Chan KH,Chang Pdoi
10.1016/j.cmpb.2013.03.018subject
Has Abstractpub_date
2013-08-01 00:00:00pages
280-9issue
2eissn
0169-2607issn
1872-7565pii
S0169-2607(13)00110-7journal_volume
111pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:T-wave alternans (TWA) is a fluctuation of the ST-T complex occurring on an every-other-beat basis of the surface electrocardiogram (ECG). It has been shown to be an informative risk stratifier for sudden cardiac death, though the lack of gold standard to benchmark detection methods has promote...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.04.005
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Type 2 diabetes mellitus (T2DM) complications seriously affect the quality of life and could not be cured completely. Actions should be taken for prevention and self-management. Analysis of warning factors is beneficial for patients, on which some previous studies focused. They generally used t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105302
更新日期：2020-05-01 00:00:00
abstract：:Rapid and accurate discrimination of single units from extracellular recordings is a fundamental process for the analysis and interpretation of electrophysiological recordings. We present an algorithm that performs detection, characterization, discrimination, and analysis of action potentials from extracellular record...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.07.001
更新日期：2004-12-01 00:00:00
abstract：:We propose a fast seed detection for automatic tracking of coronary arteries in coronary computed tomographic angiography (CCTA). To detect vessel regions, Hessian-based filtering is combined with a new local geometric feature that is based on the similarity of the consecutive cross-sections perpendicular to the vesse...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.07.005
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Accurate and fast vessel segmentation from liver slices remain challenging and important tasks for clinicians. The algorithms from the literature are slow and less accurate. We propose fast parallel gradient based seeded region growing for vessel segmentation. Seeded region growing is tedious w...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105430
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Breast cancer is the most common cancer affecting females worldwide. Breast cancer survivability prediction is challenging and a complex research task. Existing approaches engage statistical methods or supervised machine learning to assess/predict the survival prospects of patients. OBJECTIVE:The main objec...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.12.011
更新日期：2018-03-01 00:00:00
abstract：:In medical systems it is often advantageous to utilize specific problem situations (cases) in addition to or instead of a general model. Decisions are then based on relevant past cases retrieved from a case memory. The reliability of such decisions depends directly on the ability to identify cases of practical relevan...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(05)80003-3
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This contribution presents a rapid computational framework to mechanically simulate the insertion of a slender medical instrument in a tubular structure such as an artery, the cochlea or another slender instrument. METHODS:Beams are employed to rapidly simulate the mechanical behaviour of the ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105527
更新日期：2020-11-01 00:00:00
abstract：:The goal of our study is to develop a fast parallel implementation of group independent component analysis (ICA) for functional magnetic resonance imaging (fMRI) data using graphics processing units (GPU). Though ICA has become a standard method to identify brain functional connectivity of the fMRI data, it is computa...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.02.002
更新日期：2015-04-01 00:00:00
abstract：:Image registration with anatomical modalities, such as CT and MRI, facilitates the anatomical identification and localization in the interpretation of nuclear medicine images that lack anatomical information. The implementation of Functional Image Registration (FIRE), an operating system (OS) and platform independent ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.12.007
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Model-based lung mechanics monitoring can provide clinically useful information for guiding mechanical ventilator treatment in intensive care. However, many methods of measuring lung mechanics are not appropriate for both fully and partially sedated patients, and are unable provide lung mechani...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105184
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hedyotis diffusa is an herb used for anti-cancer, anti-oxidant, anti-inflammatory, and anti-fibroblast treatment in the clinical practice of Traditional Chinese Medicine. However, its pharmacological mechanisms have not been fully established and there is a lack of modern scientific verificatio...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.10.019
更新日期：2019-06-01 00:00:00
abstract：:The paper presents a computer-based assessment for facioscapulohumeral dystrophy (FSHD) diagnosis through characterisation of the fat and oedema percentages in the muscle region. A novel multi-slice method for the muscle-region segmentation in the T1-weighted magnetic resonance images is proposed using principles of t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.03.006
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data. Although there are many algorithms proposed for microarray data, the n...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.04.007
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Functional magnetic resonance imaging (fMRI) studies of the human brain are appearing in increasing numbers, providing interesting information about this complex system. Unique information about healthy and diseased brains is inferred using many types of experiments and analyses. In order to ob...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.07.015
更新日期：2016-10-01 00:00:00
abstract：:Software which provides an interface to the features of the Sound Blaster Pro card for the IBM PC using MS-DOS is described. The library may be called from a Turbo Pascal version 6 program. It permits tones of specified frequency (500 Hz-8 kHz in increments of 500Hz) and aversive noise to be turned on and off by a con...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)01588-7
更新日期：1994-12-01 00:00:00
abstract：:In muscle cells, force development is controlled by Ca2+ ions, which are rapidly released from the sarcoplasmic reticulum (SR) during sarcolemmal depolarization. In addition to this synchronized spatially homogeneous calcium signal, localized quantal Ca2+ release events (sparks) have been recorded using laser scanning...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.06.004
更新日期：2005-01-01 00:00:00
abstract：:For the first time compressed sampling (CS) has been applied to heart rate (HR) measurements. The signals can be reconstructed from samples far below the Nyquist rate with negligible small errors, a sampling reduction of 8 has been demonstrated in the paper. As a result, the bitrate of the CS sampler is half when comp...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.06.002
更新日期：2012-12-01 00:00:00
abstract：:As we continue to strive to apply the findings of in vitro and animal studies to human disease and transition from genomics to proteomics, we will experience an ever-increasing need for human tissues. A web based system that provides access to tissues repositories and associated data will best facilitate the access to...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/s0169-2607(02)00002-0
更新日期：2003-02-01 00:00:00
abstract：:The continuing education is a challenge for health care professionals, considering the growing amount and variable quality of information in this field. In this context, we developed a method allowing clinicians to have a centralised access to the best current medical evidence supporting medical decision-making. Relev...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(02)00055-x
更新日期：2003-05-01 00:00:00
abstract：:We discuss how vocal disorders can be post-corrected via a simple nonlinear noise reduction scheme. This work is motivated by the need of a better understanding of voice dysfunctions. This would entail a 2-fold advantage for affected patients: Physicians can perform better surgical interventions and on the other hand ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(01)00161-4
更新日期：2002-05-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.09.008
更新日期：2015-12-01 00:00:00
abstract：:People without disabilities seamlessly control devices with their hands. Interestingly, their hands can perform coarse and fine control. Implementing smooth control for computerized systems is not straightforward and most of the time it is not intuitive either. Here we offer a solution to that problem: smooth control ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.06.009
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Data curation is a tedious task but of paramount relevance for data analytics and more specially in the health context where data-driven decisions must be extremely accurate. The ambition of TAQIH is to support non-technical users on 1) the exploratory data analysis (EDA) process of tabular he...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.12.029
更新日期：2019-11-01 00:00:00
abstract：:In cardiology, ultrasound is often used to diagnose heart disease associated with myocardial infarction. This study aims to develop robust segmentation techniques for segmenting the left ventricle (LV) in ultrasound images to check myocardium movement during heartbeat. The proposed technique utilizes machine learning ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105914
更新日期：2020-12-17 00:00:00
abstract：:We describe the theory and computer implementation of a newly-derived mathematical model for analyzing the shape of blood pressure waveforms. Input to the program consists of an ECG signal, plus a single continuous channel of peripheral blood pressure, which is often obtained invasively from an indwelling catheter dur...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(93)90020-l
更新日期：1993-04-01 00:00:00
abstract：:This paper compares bibliographic retrieval using current MeSH (Medical Subject Headings) to bibliographic retrieval using explicitly coded semantic relationships between index terms. In a previous study, ten lists of abstracts, each list containing 20-40 papers discussing a specific pair of terms, were analyzed to id...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(88)90084-3
更新日期：1988-11-01 00:00:00
abstract：:In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.09.006
更新日期：2014-01-01 00:00:00
abstract：:A flexible program for the IBM PC performing a number of calculations of relevance for the prescription of hemodialysis treatment has been developed. The program has a 'spreadsheet'-like user-friendly interface, and results may be presented graphically. The present implementation covers 89 algorithms/equations, all ba...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(90)90009-x
更新日期：1990-03-01 00:00:00
abstract：:As health care costs have risen dramatically, the use of clinical data to analyze the quality of health care provided has increased. Central to this analysis is the means by which the clinical data itself is obtained. The reliability and validity of the data must be established in order to insure credible use of the d...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(93)90063-q
更新日期：1993-09-01 00:00:00
