Abstract:
:Meningococcal disease continues to be a great health problem on all continents and the meningococcal vaccines have been proposed for their prevention and epidemic control. The polysaccharide A and C vaccines are relatively efficacious with distinct immunological behavior with regard to the different age groups, however, up to the present no highly efficacious vaccine for meningococcal B disease exists. The meningococcal B capsular polysaccharide is not immunogenic due to the structural mimicry of mammalian tissues and efforts to produce carrier proteins have been proposed in order to obtain an immunogenic vaccine for all age groups that would if possible, protect against all the meningococci. This review of the literature presents the study of the development of the immunological behavior of all the meningococcal vaccines undergoing development and reports on the efforts to obtain a safe and efficacious product for the control of meningococcal disease.
journal_name
Rev Saude Publicajournal_title
Revista de saude publicaauthors
Requejo HIdoi
10.1590/s0034-89101997000400010subject
Has Abstractpub_date
1997-08-01 00:00:00pages
402-16issue
4eissn
0034-8910issn
1518-8787journal_volume
31pub_type
杂志文章,评审abstract:OBJECTIVE:The study aims to identify children who are not benefited by local health programs, looking for to characterize the excluded segment of the population in order to broaden the access to and use of the main actions provided by local health programs. METHODS:A sample of 465 children aged less than 1 year was st...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102000000100009
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To establish the influence of climatic factors on the monthly frequency of mosquito fauna in areas of the National Park of Serra da Bocaina, Brazil. METHODS:Human bait collections were conducted once a month, in diurnal and nocturnal hours, throughout 24 months, from January 1991 to December 1992. RESULTS:A...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102001000400010
更新日期:2001-08-01 00:00:00
abstract::In the Valdivia (Chile) river basin 1,295 inhabitants of 6 riverside districts were examined between March and October 1987 and showed a 1.2% of prevalence by Diphyllobothrium in the districts of Riñihue and Las Huellas. Prevalence of 5.3% and 9.8% respectively were registered in dogs of the districts of Riñihue and M...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101989000100007
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVE:To investigate the frequency of rural occupational accidents and its association with potential risk factors. METHODS:The study was carried out in a urban area of Pelotas, RS, Brazil. A cross-sectional study was conducted. A representative sample of rural workers was selected using a multi-stage sampling. Fr...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102001000300009
更新日期:2001-06-01 00:00:00
abstract::Adults, nymphs and nits of the Pediculus humanus were found in a frame-house infesting the clothes and bedding of three inhabitants in a shanty town in S. Paulo county, S. Paulo State. A total of 198 nits were found glued in 15.0 cm2 of fibres of the infested clothing, giving a ratio of 13.2 nits/cm2. Having in view t...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101998000100012
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:To identify and measure the risk of malnutrition associated to determining indicators of mother's ability of childcare: familial structure, education level, work, maternal physical and mental health. METHODS:A case-control study was performed. Cases (101 children whose weight/age was below 5th percentile) a...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102002000200011
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of HIV-1 subtypes and analyze factors associated. METHODS:A cross-sectional study was performed with a convenience sample of 80 adult HIV-positive patients, users of an AIDS/STD specialized service, in the city of Canoas, Southern Brazil, between July 2008 and January 2009. Determi...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102010005000039
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:To estimate the number of occupational accidents that occurred in a certain municipality during a specific period of time as well as the extent of sub-registration. METHODS:The study sample was comprised of 4.782 households within the municipality of Botucatu, São Paulo occupied by a total 17,219 inhabitant...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102003000400004
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of multimorbidity among Brazilian adults and its association with socioeconomic indicators. METHODS:Cross-sectional study that used data from the Pesquisa Nacional Sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos no Brasil (PNAUM - Brazilian National Survey on Acce...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.11606/s1518-8787.2020054002569
更新日期:2020-12-14 00:00:00
abstract::The objective of the study was to present the within-person variance component for adjusting nutrient distribution in adults and elderly people. The data used were from a population-based survey with a representative sample (n = 511) of individuals aged 19 years and over in the municipality of São Paulo, Southeastern ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102011000300022
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of adequate control of hypertension among older adults and to examine its association with predisposing and enabling factors and the need to use health services. METHODS:The analysis was carried out with 4,148 participants (≥ 50 years) from the baseline of the Brazilian Longitudina...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.11606/S1518-8787.2018052000646
更新日期:2018-10-25 00:00:00
abstract::The paper discusses the articulation among epidemiological information systems, scientific production and men's health policies. Three secondary sources were used: data from the Ministry of Health (Mortality and Hospital Information Systems, Surveillance of Protection and Risk Factors for Chronic Diseases through Tele...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102012005000061
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of hospitalizations and to identify characteristics associated with hospital admission. METHODS:We carried out a population-based cross-sectional study of subjects of both sexes, aged 20-69 years, and who lived in the urban area of Pelotas, Southern Brazil, between 1999 and 2000. S...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102010005000026
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To analyze factors associated with attention-deficit and hyperactivity disorder in children. METHODS:This is a longitudinal study about behavior problems in schoolchildren that was carried out in the city of São Gonçalo (Southeastern Brazil) in 2005. A total of 479 students from public schools was analyzed, ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102012005000043
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of chronic obstructive pulmonary disease and related risk factors. METHODS:A population-based cross-sectional study with 1,441 individuals of both sexes aged 40 years or more was conducted in the city of São Paulo, Brazil, between 2008 and 2009. A two-stage (census tract, household) ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102011005000051
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:Data from three household surveys undertaken in the city of S. Paulo, Brazil, from mid-80s to mid-90s allow to characterize and analyse secular trends in malnutrition and obesity among infants and children. METHODS:The three surveys included random population samples aged from zero to 59 months (1,008 childr...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:INTRODUCTION:Domestic violence against children has been a subject of concern to many Brazilian institutions, though there are few studies about the services offered to the community. The aim of this study is to evaluate administrative and operational aspects of the SOS Criança and provide insight to similar programs w...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101999000600005
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To describe children's consumption of processed foods and its relationship with per capita family income based on a household survey. METHODS:Food consumption was studied in a statistical sample of 718 children living in the city of São Paulo in the period 1995-1996. A 24-hour dietary recall was used. Data r...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102002000700001
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of socioeconomic variables, birth weight, duration of breastfeeding and income changes on random blood glucose levels among young adults. METHODS:This was a study on the birth cohort from 1982, when the 5,914 hospital births that occurred in the city of Pelotas (Southern Brazil) were ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102008000900013
更新日期:2008-12-01 00:00:00
abstract::The present essay is an exploratory study of the historical and institutional background of the so-called "crisis in public health", aimed at identifying the new trends and perspectives for the paradigmatic transformation of the health field in the context of the current international panorama of economic and cultural...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101998000400001
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:To analyze the spread of human American visceral leishmaniasis and identify the key municipalities for developing surveillance and control activities. METHODS:The area of the study was composed of the 316 municipalities in the state of Sao Paulo belonging to the five health districts in which human American ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/S0034-8910.2013047004454
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To assess the performance and integration between the health care and teaching dimensions in Brazilian university hospitals. METHODS:A network data envelopment analysis (DEA) model was designed to measure the performance of federal university hospitals, which enables the relationship between the teaching and...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102010000400001
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVES:Psychiatric hospitalization though burdensome remains a very important therapeutic option for severely-ill psychiatric patients. Hospitalization in general hospital psychiatry units (GHPU) are often regarded as the best option. A study was carried out with the purpose of assessing socioeconomic and medical v...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102003000500013
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To describe the evolution of the epidemiological research on physical activity in Brazil. METHODS:A systematic review of the literature was carried out in electronic databases (Medline/PubMed, Lilacs, Ovid, Science Direct, BioMed Central and High Wire), non-indexed Brazilian journals, query by specific autho...
journal_title:Revista de saude publica
pub_type: 杂志文章,评审
doi:10.1590/s0034-89102007000300018
更新日期:2007-06-01 00:00:00
abstract::Sixty small farms of Botucatu County, S. Paulo, Brazil, given over to cattle breeding were studied. These farms account for 15% of the total of 402 farms that exist in the county. The sample was drawn by simple probabilistic technique. There were found to be one hundred and thirteen drinking places located on the farm...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101992000500004
更新日期:1992-10-01 00:00:00
abstract::Further to a research project into the accuracy of death given on the causes of death given on the death certificates of women of fertile age (10-49), resident in the City of S. Paulo, SP, Brazil, in 1986, the main causes of death for the population according to age, with remarks on the mortality from cardiovascular d...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101991000100008
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:To assess the clinical-epidemiological descriptors of inpatient mortality in persons infected with the human immunodeficiency virus (HIV). METHOD:All adult HIV/AIDS patients hospitalized at a university hospital in 1990, 1992 and 1994 were studied retrospectively. Descriptive statistics for all variables of ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89101998000600011
更新日期:1998-12-01 00:00:00
abstract::The purpose of the paper is to describe 4 new cases of human diphyllobothriasis in Patagonia, Argentine. Adult parasites recovered were submitted to morphological and histological analyses for taxonomic identification. The etiological agent found was always Diphyllobothrium latum and all the cases were autochthonous. ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102001000200017
更新日期:2001-04-01 00:00:00
abstract::Federal statistic figures show that the Brazilian States altogether have, in their respective territories, a collection of taxes which is higher than the Union one. The highest collection of the Central Government which is shown at the official statistics is due to the excess of collection of the federal taxes over th...
journal_title:Revista de saude publica
pub_type: 传,古典文章,历史文章,杂志文章
doi:10.1590/s0034-89102006000500001
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:According to the World Health Organization, medicinal drug promotion should be reliable, accurate, truthful, informative, balanced, up-to-date and capable of substantiation. The objective of the present study was to review psychoactive drug advertisements to physicians as for information consistency with the ...
journal_title:Revista de saude publica
pub_type: 杂志文章
doi:10.1590/s0034-89102008005000023
更新日期:2008-06-01 00:00:00