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Relationship between age and autonomic neuropathy in diabetes mellitus.

Abstract：

:The influence of age on diabetic autonomic neuropathy was studied. In the present study autonomic neuropathy was assessed by cardiac beat-to-beat variation during deep breathing (BBV) and pupil area prior to photic stimulus (A1). In the studies on BBV a total of 440 subjects (11-82 years in age) were divided into three groups: those with a duration of diabetes of less than 5 years and without obvious diabetic complications; those with a duration of diabetes of longer than 5 years and with diabetic complications; and non-diabetic, healthy subjects. The relationship between BBV and age was examined in each group. In the studies on A1 a total of 101 subjects (22-75 years in age) were investigated in the same way. The results were as follows: (1) The autonomic nerve function of young diabetics corresponds to that of old non-diabetics in terms of cardiac beat-to-beat variation and pupil area prior to photic stimulus; (2) in young diabetics duration of diabetes and the complications influence the autonomic nerve function; (3) autonomic nerve function is related to age. Age is more influential than duration of diabetes and diabetic complications, especially in the older subjects.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Kuroda N,Taniguchi H,Baba S,Yamamoto M

doi

10.1016/0168-8227(90)90008-h

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

49-53

issue

1

eissn

0168-8227

issn

1872-8227

pii

0168-8227(90)90008-H

journal_volume

9

pub_type

杂志文章

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