Urinary amino acid excretion patterns in cancer of prostate.

Abstract:

:The excretion of urinary amino acids obtained from acid hydrolysates were studied by gas chromatographic analysis in 16 normal male subjects and 48 patients with cancer of the prostate. There were no significant differences of the most commonly excreted amimo acids in normal or patient groups or between patients with different stages of the disease because of the large variances of excretion within groups as a whole. However, with few exceptions, the patient group excreted isoleucine whereas isoleucine excretion was not detected in the normal subjects under the same experimental conditions. These findings suggest that measurement of the urinary excretion of isoleucine may be a useful parameter for the early detection of prostatic cancer.

journal_name

Urology

journal_title

Urology

authors

McGregor RF,Johnson DE

doi

10.1016/0090-4295(76)90338-1

subject

Has Abstract

pub_date

1976-08-01 00:00:00

pages

127-8

issue

2

eissn

0090-4295

issn

1527-9995

journal_volume

8

pub_type

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