Positive result by serology indicates active Helicobacter pylori infection in patients with atrophic gastritis.

Abstract:

:Patients with atrophic corpus gastritis and elevated Helicobacter pylori antibody titers but 13C-urea breath test (13C-UBT) and histology results negative for H. pylori were randomized into eradication therapy or follow-up only. Antibody levels decreased significantly in six out of seven patients in the eradication group, while in the follow-up group, the titers declined in only one out of eight patients. In patients with atrophic corpus gastritis, positive serology results may indicate an ongoing infection in spite of negative 13C-UBT and histology results.

journal_name

J Clin Microbiol

authors

Kokkola A,Rautelin H,Puolakkainen P,Sipponen P,Färkkilä M,Haapiainen R,Kosunen TU

doi

10.1128/JCM.36.6.1808-1810.1998

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

1808-10

issue

6

eissn

0095-1137

issn

1098-660X

journal_volume

36

pub_type

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