Neglect syndrome for aversive stimuli in a macaque monkey with dorsomedial frontal cortex lesion.

Abstract:

:After a session of unit activity recording, one of our monkeys presented an epileptic attack, which provoked contralateral tilting movements. The following days, the animal performed saccades and fixation tasks correctly in all directions, while contralateral arm reaching movements were severely impaired. To establish if the neurological lesion had changed the orienting performance we considered two types of stimuli, pleasant and aversive. Pleasant stimuli, presented in the ipsilateral or contralateral hemifield, readily drew the attention of the animal. If the same stimuli were presented simultaneously in both hemifields, the monkey oriented itself only toward the ipsilateral one. Aversive stimuli evoked an aggressive reaction only when the stimulus was localized in the ipsilateral hemifield. The animal clearly neglected the aversive stimulus presented in the contralateral hemifield. The animal recovered completely in 30 days. The postmortem examination revealed a lesion in the dorsomedial frontal cortex. The combined attentional and motor deficits suggest that this area may be involved in the preparation and execution of movements triggered by the affective meaning of the stimulus.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Lucchetti C,Lui F,Bon L

doi

10.1016/s0028-3932(97)00100-0

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

251-7

issue

3

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(97)00100-0

journal_volume

36

pub_type

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