GC/MS analysis of PCB congeners in blood of the harbor seal Phoca vitulina from San Francisco Bay.

Abstract:

:Here we report a validated technique for quantifying up to 20 specific PCB congeners in 1-2 g samples of whole blood with a detection limit below 1 ng/g (ppb) wet weight. Specimens were analyzed from 14 harbor seals sampled in south San Francisco Bay, California during 1991-1992. Ratios of specific congeners to PCB-153, and other aspects of congener pattern, agreed with published values for PCB's detected in seal blood. PCB-153 constituted 30 percent of our sigma PCB values. The mean sigma PCB concentration for the San Francisco Bay seals was 50 ppb, about three times the average level reported for blood of captive seals fed exclusively on fish from the Baltic's PCB-contaminated Dutch Wadden Sea. Such experimental populations have exhibited depressed reproductive success and impaired immune function. These findings support concerns about the ecological effects of PCB contamination in San Francisco Bay.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Young D,Becerra M,Kopec D,Echols S

doi

10.1016/s0045-6535(98)00075-7

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

711-33

issue

4

eissn

0045-6535

issn

1879-1298

pii

S0045653598000757

journal_volume

37

pub_type

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