Abstract：
:Dose-dependent terathogenic effects of an organophosphate insecticide were found during early sea urchin development. This biological assay is low cost, easy to measure, and allows to detect the effects of the exposure of organisms to the active principle at concentrations lower than the acceptable daily intake (ADI) for man. Effects were found independently from the stage of exposure, and were major as earlier exposure occurred. The stronger effects were exerted on the elongation of the skeletal rods, that was easily measured by following the migration of primary mesenchyme cells, labelled by WGA (wheat germ agglutinin).
journal_name
Chemospherejournal_title
Chemosphereauthors
Morale A,Coniglio L,Angelini C,Cimoli G,Bolla A,Alleteo D,Russo P,Falugi Cdoi
10.1016/s0045-6535(98)00341-5subject
Has Abstractpub_date
1998-12-01 00:00:00pages
3001-10issue
14-15eissn
0045-6535issn
1879-1298pii
S0045-6535(98)00341-5journal_volume
37pub_type
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