Abstract:
:Vivus' proprietary oral capsule containing phentermine and extended-release (ER) topiramate has been approved in the US for the treatment of obesity. Phentermine is an appetite suppressant, while topiramate is an anti-epileptic medication. The once-daily formulation, known as Qsymia™, is designed to produce weight loss by decreasing appetite and increasing satiety. The product is also in clinical development for sleep apnoea syndrome and type 2 diabetes mellitus. This article summarizes the milestones in the development of phentermine/topiramate ER leading to this first approval for obesity.
journal_name
Drugsjournal_title
Drugsauthors
Cameron F,Whiteside G,McKeage Kdoi
10.2165/11640860-000000000-00000subject
Has Abstractpub_date
2012-10-22 00:00:00pages
2033-42issue
15eissn
0012-6667issn
1179-1950pii
3journal_volume
72pub_type
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