Abstract：
:Chronic low-grade systemic inflammation plays a role in the development of cardiovascular (CV) disease. Habitual endurance exercise training reduces the risk of CV disease in part through anti-inflammatory mechanisms. The purpose of this study was to investigate the effects of age, endurance training status, and their interaction on pro-inflammatory plasma cytokines involved in the pathogenesis of CV disease. Subjects were BMI-matched young (25±3 years; endurance trained: n=9, sedentary: n=11) and older (62±5 years; endurance-trained: n=12, sedentary: n=11) men. Plasma cytokine concentrations were determined by multiplex cytometric bead assay. Soluble intercellular adhesion molecule-1 (sICAM-1) levels were 40% higher in sedentary older men compared to young sedentary subjects (P=0.048), but they were not different between the young and older trained men. Furthermore, sICAM-1 levels were negatively correlated with maximal oxygen uptake (V˙O2max; r= - 0.38, P=0.01) across all subjects. There were no significant differences among the groups in plasma concentrations of monocyte chemoattractant protein-1 (MCP-1), soluble tumor necrosis-α receptor (sTNFR), soluble CD40 ligand (sCD40L), or resistin. We conclude that habitual endurance training is associated with an attenuated age-related increase in plasma sICAM-1.
journal_name
Int J Sports Medjournal_title
International journal of sports medicineauthors
Many GM,Jenkins NT,Witkowski S,Damsker JM,Hagberg Jdoi
10.1055/s-0032-1316317subject
Has Abstractpub_date
2013-03-01 00:00:00pages
253-7issue
3eissn
0172-4622issn
1439-3964journal_volume
34pub_type
杂志文章abstract：:The effects of long distance running training (up to 40km/day) on the biomechanical properties of young canine articular cartilage were investigated using in situ indentation creep technique. The stiffness of articular cartilage was determined in the form of instantaneous and equilibrium shear moduli. The rate of cart...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-1021056
更新日期：1994-07-01 00:00:00
abstract：:We used continuous electrocardiographic monitoring according to Holter's method for a tentative evaluation of the prognostic value of the main electrocardiographic peculiarities of the "athlete's heart". Five hundred and eighty-seven Holter recordings were performed in 164 top athletes divided into three groups: dynam...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-1024674
更新日期：1991-04-01 00:00:00
abstract：:Hypertension is not uncommon in childhood and adolescence; vascular and renal causes predominate. Non-pharmacologic therapy, including exercise, may lower blood pressure (BP). There are several articles relating to the use of exercise as a therapy for high BP. Most of these show a beneficial effect. The "dose" of exer...
journal_title：International journal of sports medicine
pub_type： 杂志文章,评审
doi：10.1055/s-2000-8497
更新日期：2000-11-01 00:00:00
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journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2006-924516
更新日期：2007-06-01 00:00:00
abstract：:Muscular deficits in the hip abductors are presumed to be a major factor in the development of Iliotibial Band Syndrome in runners. No definite relationship between muscular weakness of the hip abductors and the development of Iliotibial Band Syndrome or different ratios between hip adduction to abduction have been re...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-989323
更新日期：2008-07-01 00:00:00
abstract：:The indirect identification of doping in sports can be performed by assessing athletes' hematological perturbations from the analysis of blood collected on different occasions. Because prosecution for doping based on this information requires expensive and time-consuming interpretation of blood analysis results by var...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/a-1019-7774
更新日期：2020-01-01 00:00:00
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journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2008-1038620
更新日期：2008-11-01 00:00:00
abstract：:Fourteen male physical education students performed a single bout of running until exhaustion on the treadmill at 22 km/h and 7.5% slope. They received single oral doses of 100 mg bupranolol (nonselective beta-blockade), 100 mg metoprolol (beta-1-selective blockade), and placebo 60-90 min before running. Arterialized ...
journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2008-1026050
更新日期：1983-11-01 00:00:00
abstract：:Decreased ability to perform activities of daily living (ADLs) associated with deterioration in physical capacity are key determinants of the poor quality of life and loss of independence of patients with Alzheimer's disease (AD). The purpose of this study was to determine the effects of a 12-week training program (in...
journal_title：International journal of sports medicine
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-2008-1038432
更新日期：2008-10-01 00:00:00
abstract：:Signs of overuse after intense muscular exertion are well described in adults, while little research has been conducted in children. The aim of the study was to investigate some indirect markers of muscle damage in 13 years old boys following two different protocols of one-leg stepping exercise to exhaustion. This ste...
journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2007-971101
更新日期：1999-02-01 00:00:00
abstract：:The purpose of this randomized cross-over study was to investigate the effects of a 4-min long, 2-mm vertically-vibrating vibration-exercise on muscle performance and body balance in healthy subjects. Sixteen volunteers (eight men and women aged 18-35 years) underwent both the 4-min vibration- and sham-interventions i...
journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2002-33148
更新日期：2002-07-01 00:00:00
abstract：PURPOSE:The modified Dmax method can accurately determine the second lactate threshold (LT2), which is valuable for predicting aerobic performance and prescribing exercise. The purpose of this study is to determine if the modified Dmax method can accurately find thresholds in VE (VT2), VCO2 (VCO2T), RER (RERT), and RR ...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0043-125448
更新日期：2018-04-01 00:00:00
abstract：:The present study investigated the difference in blood glucose concentration (Glu) response during an incremental swimming test before and after a ten-week training period and verified whether blood glucose threshold (GT) could be determined in competitive swimmers. 7 elite male university swimmers participated in thi...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0031-1279778
更新日期：2011-11-01 00:00:00
abstract：:This study was undertaken to determine which of the two commonly used field tests, the 20-meter shuttle run test (20-MST) or the University of Montreal track test (UM-TT), provides the most accurate assessment of maximal and functional aerobic capacity in moderately trained athletes. Eleven male subjects aged from 18 ...
journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2007-1021261
更新日期：1992-04-01 00:00:00
abstract：:Dietary intake, plasma lipids, lipoprotein and apolipoprotein levels, anthropometric measurements and anaerobic performance were studied in eleven judo athletes during a period of weight maintenance (T1) and after a 7d food restriction (T2). Dietary data were collected using a 7-day diet record. Nutrient analysis indi...
journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章
doi：10.1055/s-2001-16244
更新日期：2001-08-01 00:00:00
abstract：:Seventeen healthy male volunteers participated in this study designed to compare arterial with both arterialized venous and venous lactate kinetics after short exercise. Blood samples drawn before, during, and after bicycle exercise were analyzed continuously for lactate. A mathematical function incorporating two expo...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-1024867
更新日期：1989-02-01 00:00:00
abstract：:The use of 60%-95% of maximal heart rate (HR), heart rate reserve (HRR) and VO2max as exercise training intensities was examined in male runners, and these intensities were related to VO2 observed at the lactate threshold (LT) and fixed blood lactate concentrations (FBLC) of 2.0, 2.5, and 4.0 mM. Thirty-one subjects (...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-1024795
更新日期：1990-06-01 00:00:00
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journal_title：International journal of sports medicine
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-0033-1343402
更新日期：2013-12-01 00:00:00
abstract：:In a study of the effects of motion load on weight-bearing articular cartilage, rabbits were made to run on a treadmill for 1-, 5-, and 30-day periods. One group ran on a level surface, and another ran uphill. In vivo 35S-sulfate bound in glycosaminoglycans (GAG) after running was used as an indicator of the synthesis...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2008-1025925
更新日期：1984-12-01 00:00:00
abstract：:As golf grows in popularity, golf related injuries have increased. The purpose of this study was to calculate and compare upper body kinematics of healthy male golfers from different skill levels. Kinematic data were obtained from 18 professional, 18 low handicap, 18 mid handicap and 18 high handicap golfers with an o...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-989229
更新日期：2008-06-01 00:00:00
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journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2008-1025721
更新日期：1987-12-01 00:00:00
abstract：:This study examined muscular adaptations of knee extensors following short-term low-frequency downhill walking training. 22 young males (training group: TG, n=12; control group: CG, n=10) participated. TG conducted 40-min downhill treadmill walking (load: 10% of body mass, gradient: 28%, velocity: 5 km/h) 1 session/we...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0034-1385885
更新日期：2015-02-01 00:00:00
abstract：:This study investigated the effects of marine phytoplankton supplementation on 1) perceived recovery and ground reaction forces in humans following a non-functional overreaching resistance-training program and 2) myogenic molecular markers associated with muscle cell recovery in a rat model. In the human trial, a 5-we...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/a-1320-1061
更新日期：2020-12-22 00:00:00
abstract：:Caffeine enhances endurance performance; however, its effect on accumulated lactate remains unclear. Conversely, taurine, which also enhances endurance performance, decreases accumulated lactate. In this study, the effect of combination of caffeine and taurine on endurance performance was assessed. Mice ran on a tread...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0028-1104574
更新日期：2009-07-01 00:00:00
abstract：:Highly repetitive submaximal intermittent contractions of the forearm muscles during periods of 30-50 min partially explain why motorcycle races are so demanding for the neuromuscular system. This study investigated the contribution of central and peripheral mechanisms of fatigue on the exerted and contralateral exten...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0035-1549959
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:In international cycling and cross-country skiing competitions, blood tests are used to unmask the performance enhancing misuse of erythropoietin. Haematocrit (cycling) and haemoglobin (cross-country skiing) limits have been set by international sporting federations (haematocrit 50%, haemoglobin 18.5 g/dl). ...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2000-3785
更新日期：2000-07-01 00:00:00
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journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2003-42017
更新日期：2003-10-01 00:00:00
abstract：:Prospective studies on overuse injuries and their impact on athletic training among youth team sports are scarce. The purpose of this study was to investigate the incidence, severity and player related risk factors of overuse injuries among young (12-20 years) basketball and floorball players. A total of 387 players p...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0043-114864
更新日期：2017-10-01 00:00:00
abstract：:The accumulated O2 deficit (the difference between the estimated energy demand and the actual O2 uptake) was determined during intense exhaustive exercise (2-7 min) in elite athletes, and its relationship with muscle buffer capacity, muscle enzymes and muscle morphology was examined. Five oarsmen, fifteen soccer playe...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-2007-1021165
更新日期：1993-05-01 00:00:00
abstract：:This study investigated the validity of determining the final work rates of cycling and walking ramp-incremented maximal cardiopulmonary exercise tests (CPETs) using a non-exercise model to predict maximal oxygen uptake VO2max and the American College of Sports Medicine ACSM's metabolic equations. The validity of usin...
journal_title：International journal of sports medicine
pub_type： 杂志文章
doi：10.1055/s-0034-1395590
更新日期：2015-10-01 00:00:00
