Abstract:
BACKGROUND:Although clinical trials are needed to evaluate the efficacy of liquid herbal medicinal products, design of feasible placebos that mimic the appearance, taste, and smell of such products is particularly challenging. OBJECTIVE:The design and feasibility of a liquid placebo for STW5, an herbal medicinal product used for various gastrointestinal problems, was explored in this study. DESIGN:Four sample products-STW5, a fresh and aged version of a placebo made from a seasoning mix (Maggi™), and a placebo with aged artificial flavor and food coloring-were compared in two organoleptic (sensory), single-blind trials with a total of 60 (N=60) healthy volunteers (n(1)=30, n(2)=30). MEASUREMENTS:The appearance, smell, and taste of each solution were evaluated using a Likert scale questionnaire. RESULTS:The liquid placebos evaluated were similar in regard to appearance, smell, and taste. However, participants indicated that for a clinical trial with STW5, the aged Maggi™ placebo would be more viable compared to the fresh Maggi placebo or the aged artificial food coloring placebo with licorice flavor. Participants also noted that the mint flavor and smell of STW5 was distinctly different from the placebo solutions. LIMITATIONS:The trials were conducted in healthy volunteers, not in actual patients. CONCLUSIONS:The aged Maggi™ liquid mix may be more favorable as a placebo than the artificially created one. However, further adjustment will need to be made to the Maggi™ placebo to simulate the complex aromatic composition of STW5 for clinical studies in the future.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Yoon SL,Grundmann O,Keane D,Urbano T,Moshiree Bdoi
10.1016/j.ctim.2012.04.003subject
Has Abstractpub_date
2012-10-01 00:00:00pages
267-74issue
5eissn
0965-2299issn
1873-6963pii
S0965-2299(12)00070-2journal_volume
20pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Over one-third of cardiac patients practice Mind-Body Therapy (MBT), particularly women. Considering women are less likely to engage in conventional physical activity, few studies have examined why MBT is well-accepted by women. OBJECTIVES:To qualitatively explore gender differences in the motivations for, ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2008.04.009
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study is to a) investigate the headache features and level of headache severity, chronicity, and disability found within a chiropractic patient population and b) to ascertain if patient satisfaction with headache management by chiropractors is associated with headache group or reason for cons...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.102276
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abstract::Writers on homoeopathy frequently refer to classical homoeopathy, usually with the implication that this is the most complete and authoritative version of Hahnemann's views. However, such claims do not correspond with the historical facts. Homoeopathy arrived in the USA early in the 19th century and there underwent co...
journal_title:Complementary therapies in medicine
pub_type: 历史文章,杂志文章,评审
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更新日期:1999-06-01 00:00:00
abstract::In this paper I critically address what is becoming the wholesale adoption of the concept of complementary medicine in researchers' analyses of lay participation in alternative therapies. This paper emerged out of a qualitative study of 21 Canadians who use and/or practice alternative therapies. I found that only seve...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1054/ctim.2000.0423
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To study the effectiveness of electro-acupuncture with behavior therapy on preschool children with attention deficit hyperactivity disorder (ADHD). METHODS:180 preschool children with ADHD diagnosed by DSM-IV were classified into three subtypes: predominantly inattentive subtype (PI subtype, 60 cases), predo...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2010.08.002
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:To explore First Year medical students' rating of CAM therapies following a core teaching session. To determine the influence of student gender and previous experience of CAM and therapist/teacher gender and professional background on ratings. DESIGN:Survey; self-administered questionnaire following a teach...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1054/ctim.2002.0501
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of functional-task training on activities of daily living (ADL) in people with Parkinson`s Disease. METHODS:We searched five databases (Cinahl, Embase, Medline, Pedro and CENTRAL). The included studies were assessed on therapeutic validity and risk of bias. We classified the quality of...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2018.12.008
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abstract:OBJECTIVES:The study examines the difference in characteristics between primary care patients who turn to "religious resources for medical purposes" (RRMP) and those who turn to "complementary or alternative medicine" (CAM) services to cope with a physical or mental health problem. DESIGN AND SETTING:Data were collect...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2013.08.010
更新日期:2013-10-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2013.04.003
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2006.06.006
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:This qualitative study aimed to explore medical specialists' perspectives on a proposed academic integrative healthcare (IHC) centre to be established in their local district. METHODS:A convenience sample of medical specialists were recruited via direct email invitations that was augmented with snowball sam...
journal_title:Complementary therapies in medicine
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doi:10.1016/j.ctim.2020.102530
更新日期:2020-09-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ctim.2010.09.001
更新日期:2011-01-01 00:00:00
abstract::This study aimed to evaluate questionnaire development to measure the knowledge of Complementary-Alternative Medicine (CAM), attitudes towards CAM, CAM experiences, and CAM educational needs of clinical psychologists in Indonesia. A 26-item questionnaire was developed through an extensive literature search. Data was o...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2017.05.003
更新日期:2017-08-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2014.01.006
更新日期:2014-04-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2006.05.002
更新日期:2006-09-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.09.003
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The importance of mind-body oriented therapies in oncology has increased in recent years. Eurythmy therapy (EYT, Greek: eurythmy=harmonious rhythm) is a mind-body oriented therapy used in Anthroposophic Medicine. EYT can lead to long-term alleviation of chronic disease symptoms and improve patient quality of...
journal_title:Complementary therapies in medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.ctim.2008.09.005
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:This study illustrates that direct electrical stimulation (ES) improve functional recovery and time of return to work evaluated by prognostic scoring system after ulnar nerve injury. DESIGN:The Rosén and Lundborg (R&L) protocol, Disabilities of the Arm, Shoulder and Hand (DASH) scores, and electromyography w...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2005.10.003
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2014.09.006
更新日期:2014-12-01 00:00:00
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journal_title:Complementary therapies in medicine
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doi:10.1016/j.ctim.2014.08.002
更新日期:2014-10-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2011.12.008
更新日期:2012-06-01 00:00:00
abstract::This study examined Eastern (Singapore) and Western (United Kingdom) attitudes and beliefs towards complementary and alternative medicine (CAM), and towards orthodox medicine (OM). In all 60 individuals from Singapore and 50 from the United Kingdom (total n = 110) filled in an 8-page questionnaire. UK participants wer...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2008.02.009
更新日期:2008-10-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2013.04.006
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:Mind-body practices (MBP), such as Yoga or Tai-Chi, have increased in popularity in the past 25 years in the US. These activities may help promote a less sedentary lifestyle and may have positive effects on health. The objective of the present study is to understand the prevalence and trends of MBP in US adu...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102501
更新日期:2020-08-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
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更新日期:2009-08-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102516
更新日期:2020-08-01 00:00:00
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journal_title:Complementary therapies in medicine
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更新日期:2020-05-01 00:00:00
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