Abstract：
BACKGROUND AND OBJECTIVES:Nowadays, the conventional thyroidectomy may appear an overly aggressive treatment in patients undergoing intervention for small suspicious lesions harboring in low volume glands. In these cases a minimally invasive approach may be a safe and appropriate option. This work aims to evaluate the effectiveness of minimally invasive thyroidectomy in patients indicated to surgery for small lesions with preoperative suspicion of malignancy. PATIENTS AND METHODS:71 patients, undergoing minimally invasive total thyroidectomy as a single procedure between May 2005 and April 2009, were enrolled in this study. They were indicated to surgery for small suspicious or malignant lesions (up to 20 mm lenght by US; cT1 according to UICC 2002) and satisfied the inclusion criteria of minimally invasive thyroidectomy, with gland volume up to 25 ml, no evidence of locally advanced disease and no previous neck surgery. The outcomes were considered in terms of complication rate, postoperative pain, hospitalisation stay, cosmetic results and completeness of surgical resection in malignancies. RESULTS:A low complication rate was registered. The surgical completeness, with mean serum thyroglobulin of 4.41 +/- 4.03 ng/ml and radioiodine uptake of 2.91 +/- 2.46%, was considered acceptable if compared with other experiences reported in literature. Excellent results with respect to patient comfort, postoperative pain and cosmetic outcome were obtained. CONCLUSION:This study confirms, where a correct selection of patients is made, the safety and the effectiveness of minimally invasive approach in the treatment of small suspicious and malignant nodules, which seem to represent its best indication.
journal_name
Eur Rev Med Pharmacol Scijournal_title
European review for medical and pharmacological sciencesauthors
Zullino A,Maiuolo A,Fumarola A,Gargiulo P,Mercuri V,Pacini FM,Ruggieri Msubject
Has Abstractpub_date
2012-04-01 00:00:00pages
519-24issue
4eissn
1128-3602issn
2284-0729journal_volume
16pub_type
杂志文章abstract：OBJECTIVE:To uncover the role of UPF1 in alleviating the progression of glioma via targeting long non-coding RNA (lncRNA) CYTOR and underlying mechanism. PATIENTS AND METHODS:A total of 30 glioma tissues surgically resected from glioma patients and 30 brain tissues were collected from brain trauma patients undergoing ...
journal_title：European review for medical and pharmacological sciences
pub_type： 杂志文章
doi：10.26355/eurrev_201911_19567
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abstract：OBJECTIVE:Isthmocele represents a reservoir on the anterior wall of the uterine isthmus or of the cervical canal at the site of a previous cesarean delivery scar. Recently, it has been clarified that it might be the cause of several gynecologic symptoms, as most common abnormal uterine bleeding. Hysteroscopy and trans-...
journal_title：European review for medical and pharmacological sciences
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更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the influence of long non-coding ribonucleic acid (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) on neuronal apoptosis in rats with cerebral infarction (CI), and to further explore the underlying mechanism of lncRNA ANRIL in the occurrence and development of ...
journal_title：European review for medical and pharmacological sciences
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abstract：OBJECTIVE:To explore the influence of micro ribonucleic acid (miR)-154 on myocardial apoptosis in rats with acute myocardial infarction (AMI), and to analyze whether Wnt/β-catenin signaling pathway was involved in the regulation. MATERIALS AND METHODS:The Sprague-Dawley (SD) rat model of AMI was established via ligati...
journal_title：European review for medical and pharmacological sciences
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abstract：OBJECTIVE:To evaluate the effect and mechanism of bone marrow stem cells (BMSCs) modified with CXCR-4 gene combined with stromal derived factor-1α (SDF-1α) in the treatment of acute spinal cord injury (SCI) in rats. MATERIALS AND METHODS:CXCR-4 gene was transfected by a virus. Spinal cord injury rats were randomly div...
journal_title：European review for medical and pharmacological sciences
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abstract：:Drug-induced liver diseases (DILD) are clinico-pathologic patterns of liver injury caused by drugs or other foreign compounds. Steatohepatitis is a rare form of DILD, and drugs account for fewer than 2% of non-alcoholic steatohepatitis (NASH). Drugs known to be capable of inducing steatosis and steatohepatitis can be ...
journal_title：European review for medical and pharmacological sciences
pub_type： 杂志文章,评审
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abstract：OBJECTIVE:The aim of this study was to investigate the expression level of microRNA-21-5p and its target gene PLAG1 in the serum of patients with spinal cord injury (SCI), as well as the role and mechanism of microRNA-21-5p in lipopolysaccharide-induced primary microglial inflammation. PATIENTS AND METHODS:The levels ...
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abstract：AIMS AND BACKGROUND:We investigated the efficacy of docetaxel plus prednisone in Italian patients with metastatic hormone-refractory prostate cancer (mHRPC). METHODS:Twenty four patients with mHRPC received docetaxel 75 mg/m2 every 3 weeks plus prednisone 5 mg twice daily for up to six cycles. The primary endpoint was...
journal_title：European review for medical and pharmacological sciences
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更新日期：2011-03-01 00:00:00
abstract：BACKGROUND & OBJECTIVES:Memory B cells represent 30-60% of the B cell pool and can be subdivided in IgM memory and switched memory. IgM memory B cells differ from switched because they express IgM and their frequency may vary from 20-50% of the total memory pool. Switched memory express IgG, IgA or IgE and lack surface...
journal_title：European review for medical and pharmacological sciences
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更新日期：2004-09-01 00:00:00
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更新日期：2018-10-01 00:00:00
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更新日期：2016-07-01 00:00:00
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journal_title：European review for medical and pharmacological sciences
pub_type： 杂志文章,评审
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更新日期：2012-02-01 00:00:00
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更新日期：2012-02-01 00:00:00
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更新日期：2014-01-01 00:00:00
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更新日期：2013-11-01 00:00:00
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更新日期：2010-06-01 00:00:00
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