当前位置： SCI文献检索 > European Review for Medical and Pharmacological Sciences期刊下所有文献 > Long non-coding RNA expression profile in permanent atrial fibrillation patients with rheumatic heart disease.

Long non-coding RNA expression profile in permanent atrial fibrillation patients with rheumatic heart disease.

Abstract：

OBJECTIVE:Atrial fibrillation (AF) is the most common type of arrhythmia, especially in rheumatic heart disease (RHD) patients. The differences in structural remodeling and electrical remodeling between the left and right atrium associated with AF in RHD patients are well known, and alterations in the expression profiles of long noncoding RNAs (lncRNAs) in the left atrium have also been investigated. However, the role of lncRNAs in the right atrium (RA) remains largely unknown. PATIENTS AND METHODS:We identified differentially expressed lncRNAs in RA tissues of RHD patients with AF or a normal sinus rhythm (NSR) using microarray analysis. Then, we performed gene ontology (GO) and KEGG pathway analyses for functional annotation of the deregulated lncRNAs. Finally, we constructed a lncRNA-mRNA co-expression network. RESULTS:Of the 22,829 human non-coding RNAs analyzed, a total of 1,909 long non-coding RNAs were detected. A total of 182 lncRNAs (117 downregulated and 65 upregulated) were shown to be differentially expressed (fold-change > 1.5) in AF patients compared with NSR patients. Many lncRNAs might be partially involved in an AF-related pathway. CONCLUSIONS:AF dysregulates the expression of lncRNAs in the RA of RHD patients. These findings may be useful for exploring potential therapeutic treatments for AF in RHD patients.

journal_name

Eur Rev Med Pharmacol Sci

journal_title

European review for medical and pharmacological sciences

authors

Mei B,Liu H,Yang S,Liang MY,Yue Y,Huang SQ,Hou J,Chen GX,Wu ZK

doi

10.26355/eurrev_201810_16165

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

6940-6947

issue

20

eissn

1128-3602

issn

2284-0729

journal_volume

22

pub_type

杂志文章

相关文献

European Review for Medical and Pharmacological Sciences文献大全
  • Clinical efficacy of mouse nerve growth factor plus nimodipine in neonatal intracranial hemorrhage and its effect on plasma PAF, CNP, MMP-2, and neurological function.

    abstract：OBJECTIVE:To investigate the clinical efficacy of combination of mouse nerve growth factor (NGF) and nimodipine in the treatment of neonatal intracranial hemorrhage (NICH) and its effect on plasma platelet-activating factor (PAF), C-type natriuretic peptide (CNP), matrix metalloproteinase-2 (MMP-2), and neurological fu...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202101_24387

    authors： Pei LN,Liu XH,Zhang H,Zhu J,Gao Z,Bi MZ

    更新日期：2021-01-01 00:00:00

  • LncRNA SNHG7 promotes development of breast cancer by regulating microRNA-186.

    abstract：OBJECTIVE:To elucidate the biological functions of long non-coding RNA (lncRNA) SNHG7 in breast cancer (BC), and its underlying mechanism in the occurrence and progression of BC. PATIENTS AND METHODS:The expression of SNHG7 in 72 pairs of BC tissues and paracancerous tissues was detected by quantitative Real-time poly...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201811_16403

    authors： Luo X,Song Y,Tang L,Sun DH,Ji DG

    更新日期：2018-11-01 00:00:00

  • Long-term (12 to 18 months) functional voice assessment to detect voice alterations after thyroidectomy.

    abstract：OBJECTIVES:Even when thyroidectomy preserves vocal cord motility it may leave patients with changes in voice quality. Although superior laryngeal nerve (LSN) damage after thyroidectomy manifests with aspecific symptoms, laryngoscopy discloses only slight morphological changes that are difficult to assess. We want to in...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Minni A,Ruoppolo G,Barbaro M,Di Lorenzo E,Sementilli G,Bononi M

    更新日期：2014-01-01 00:00:00

  • Effects of vitamin D levels on asthma control and severity in pre-school children.

    abstract：OBJECTIVE:Prevalence of asthma and vitamin D deficiency has been increasing and leading to significant morbidities. This study aimed to compare the vitamin D levels in the pre-school children with asthma and in healthy controls and to assess the relationship between vitamin D levels and asthma clinical parameters and c...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Turkeli A,Ayaz O,Uncu A,Ozhan B,Bas VN,Tufan AK,Yilmaz O,Yuksel H

    更新日期：2016-01-01 00:00:00

  • Isolation of viable Toxoplasma gondii cysts from brain samples for oral infection.

    abstract：AIM:A method was developed to separate contaminant-free viable Toxoplasma gondii cysts from brain samples of infected mice for molecular biology studies and reinfection. MATERIALS AND METHODS:The mice brains were homogenized and washed with phosphate buffered saline (PBS) Tween 80 prior to fractionation using 19-22% ...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Puvanesuaran VR,Ibrahim N,Noordin R,Balakrishnan V

    更新日期：2012-09-01 00:00:00

  • Correlation analysis of MR/CT on colorectal cancer lymph node metastasis characteristics and prognosis.

    abstract：OBJECTIVE:Colorectal cancer incidence showed increasing trend with living standard improvement and lifestyle changes. This study investigated the relationship and diagnostic value of colorectal cancer lymph node metastasis and prognosis using magnetic resonance (MR) and computed tomography (CT). PATIENTS AND METHODS:S...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Zhou L,Wang JZ,Wang JT,Wu YJ,Chen H,Wang WB,Cao F,Cheng GX

    更新日期：2017-03-01 00:00:00

  • Wildfire and COVID-19 pandemic: effect of environmental pollution PM-2.5 and carbon monoxide on the dynamics of daily cases and deaths due to SARS-COV-2 infection in San-Francisco USA.

    abstract：OBJECTIVE:The wildfire allied environmental pollution is highly toxic and can cause significant wide-ranging damage to the regional environment, weather conditions, and it can facilitate the transmission of microorganisms and diseases. The present study aims to investigate the effect of wildfire allied pollutants, part...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202010_23253

    authors： Meo SA,Abukhalaf AA,Alomar AA,Alessa OM

    更新日期：2020-10-01 00:00:00

  • Bioinformatics analysis of Exonic Splicing Enhancers (ESEs) for predicting potential regulatory elements of hTERT mRNA splicing.

    abstract：OBJECTIVES:Alternative splicing of human telomerase reverse transcriptase (hTERT) has an important effect on regulating telomerase activity. Exonic splicing enhancers (ESEs) are a family of conserved splicing factors that participate in multiple steps of the splicing pathway. Our aim is to analyze the ESEs for predicti...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Wang F,Chang GM,Geng X

    更新日期：2014-01-01 00:00:00

  • Ulinastatin improves myocardial ischemia-reperfusion injury in rats through endoplasmic reticulum stress-induced apoptosis pathway.

    abstract：OBJECTIVE:To investigate the protective role of ulinastatin (UTI) on myocardial ischemia-reperfusion (I/R) injury in rats via endoplasmic reticulum stress (ERS)-induced apoptosis pathway. MATERIALS AND METHODS:A total of 60 rats were randomly divided into normal group (n=20), myocardial I/R model group (model group, n...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202005_21366

    authors： Lun MH,Jin XY,Wang MY,Cai Z,Du W,Huang ZQ

    更新日期：2020-05-01 00:00:00

  • Impression cytological study for ocular surface disorders of late stage eye burns.

    abstract：OBJECTIVE:This study aims to explore the ocular surface of late stage eye burns by impression cytology (IC) and analyze the cytological changes and their relationship to ocular surface abnormalities. PATIENTS AND METHODS:68 eyes with late stage eye burns (thermal burn: 28 eyes; alkali burn: 26 eyes; acid burn: 14 eyes...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Zhu YF,Zheng LB,Yao YF

    更新日期：2016-01-01 00:00:00

  • Dehydroepiandrosterone supplementation improves ovarian reserve and pregnancy rates in poor responders.

    abstract：OBJECTIVE:We investigated whether DHEA supplementation had an impact on ovarian reserve parameters and pregnancy rates in patients with poor ovarian response (POR) and primary ovarian insufficiency (POI). PATIENTS AND METHODS:A total of 34 people, 6 patients with POI and 28 patients with POR, were included in the stud...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202009_22856

    authors： Ozcil MD

    更新日期：2020-09-01 00:00:00

  • Upregulation of miR-504-3p is associated with favorable prognosis of acute myeloid leukemia and may serve as a tumor suppressor by targeting MTHFD2.

    abstract：OBJECTIVE:Deregulated expression of miRNAs contributes to the development of acute myeloid leukemia (AML). miR-504-3p, one of these miRNAs, has been found have upregulated expression in various human malignancies. Our present study aimed to detect the expression of miR-504-3p and its biological effect in AML. PATIENTS...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201902_17013

    authors： Li SM,Zhao YQ,Hao YL,Liang YY

    更新日期：2019-02-01 00:00:00

  • MicroRNA-183-5p suppresses the malignant progression of osteosarcoma via binding to AKT.

    abstract：OBJECTIVE:To clarify the role of microRNA-183-5p in the malignant progression of osteosarcoma (OS) and the potential mechanism. PATIENTS AND METHODS:Relative level of microRNA-183-5p in 40 paired OS tissues and matched normal tissues was determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). Correla...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201910_19127

    authors： Shao JH,Yuan S,Qian QR,Zhu J

    更新日期：2019-10-01 00:00:00

  • Association between BMP4 expression and pathology, CT characteristics and prognosis of non-small cell lung cancer.

    abstract：OBJECTIVE:To investigate the association between bone morphogenetic protein 4 (BMP4) expression and clinical pathology, computed tomography (CT) characteristics and prognosis of patients with non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:A total of 76 NSCLC patients treated in our hospital from July 2012 to...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201907_18317

    authors： Ju FJ,Meng FQ,Hu HL,Liu J

    更新日期：2019-07-01 00:00:00

  • LncRNA SNHG1 overexpression regulates the proliferation of acute myeloid leukemia cells through miR-488-5p/NUP205 axis.

    abstract：OBJECTIVE:To elucidate the function of long non-coding RNA (lncRNA) SNHG1 in acute myeloid leukemia (AML) and to explore its biological mechanism. PATIENTS AND METHODS:Expression levels of lncRNA SNHG1 and miR-488-5p in AML cell lines pAML and THP-1 were determined by quantitative Real Time-Polymerase Chain Reaction (...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201907_18334

    authors： Bao XL,Zhang L,Song WP

    更新日期：2019-07-01 00:00:00

  • LncRNA AK024094 aggravates the progression of breast cancer through regulating miRNA-181a.

    abstract：OBJECTIVE:The aim of this study was to investigate the role of long noncoding ribonucleic acids (lncRNAs) AK024094 in regulating the progression of breast cancer (BCa) and the potential mechanism. Our findings might help to provide a theoretical basis for the targeted therapy of BCa. PATIENTS AND METHODS:The relative ...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202002_20369

    authors： Zheng TZ,Li YT,Li WJ

    更新日期：2020-02-01 00:00:00

  • Serum and follicular fluid irisin levels in poor and high responder women undergoing IVF/ICSI.

    abstract：OBJECTIVE:We examined the follicular fluid (FF) and serum levels of irisin in high and poor responders undergoing IVF/ICSI to test whether irisin has a role in the metabolic regulation of energy homeostasis in growing follicle. PATIENTS AND METHODS:Twenty infertile women with PCOS and 20 poor responder participants un...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Acet M,Celik N,Acet T,Ilhan S,Yardim M,Aktun HL,Basaranoglu S,Deregozu A,Aydin S

    更新日期：2016-05-01 00:00:00

  • LncRNA HOXA-AS2 accelerates the proliferation and migration and inhibits the apoptosis of vascular smooth muscle cells by absorbing miRNA-877-3p.

    abstract：OBJECTIVE:The aim of this study was to clarify the role of long non-coding RNA (lncRNA) HOXA-AS2 in influencing the proliferative, migratory and apoptotic abilities of human aortic vascular smooth muscle cells (HA-VSMCs) by absorbing microRNA-877-3p (miRNA-877-3p). MATERIALS AND METHODS:HOXA-AS2 level in HA-VSMCs trea...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202001_19934

    authors： Fan TT,Liu YX,Wang XC,Xu BL,Chen ZC,Lu HA,Zhang M

    更新日期：2020-01-01 00:00:00

  • Influence of miR-199a on rats with non-small cell lung cancer via regulating the HIF-1α/VEGF signaling pathway.

    abstract：OBJECTIVE:Micro-ribonucleic acids (miRNAs) are involved in the occurrence of various cancers, and the hypoxia-inducible factor 1-α (HIF-1α) is the main regulator of cell proliferation induced by hypoxia. The relationships of miR-199a and HIF-1α expressions with non-small cell lung cancer (NSCLC) remain unclear, so they...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201912_19675

    authors： Wang LM,Zhang LL,Wang LW,Zhu L,Ma XX

    更新日期：2019-12-01 00:00:00

  • MiR-155 affects proliferation and apoptosis of bladder cancer cells by regulating GSK-3β/β-catenin pathway.

    abstract：OBJECTIVE:GSK-3β negatively regulates Wnt/β-catenin signaling pathway. The abnormal miR-155 expression is associated with bladder cancer. Bioinformatics analysis revealed a complementary binding site between miR-155 and GSK-3β mRNA. This study investigated the role of miR-155 in the proliferation and apoptosis of bladd...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201907_18305

    authors： Dong ZC,Zhang D,Zhang XX,Yao ZQ,Wu H,Chen CH,Tian JQ

    更新日期：2019-07-01 00:00:00

  • MiR-5195-3p inhibits the proliferation of glioma cells by targeting BIRC2.

    abstract：OBJECTIVE:The aim of this study was to investigate the effects of microRNA-5195-3p (miR-5195-3p) on the proliferation of glioma cells and to explore its related mechanisms. PATIENTS AND METHODS:The expression level of miR-5195-3p in glioma tissues and cell lines was detected by quantitative Real Time-Polymerase Chain ...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202001_19921

    authors： Yang J,Yan DM,Xhu LX,Si DM,Liang QH

    更新日期：2020-01-01 00:00:00

  • Laboratory evaluation of Ethiopian local plant Phytolacca dodecandra extract for its toxicity effectiveness against aquatic macroinvertebrates.

    abstract：:In this study, we evaluated the toxicity effectiveness of berries crude extract of Endod [vernacular name (local native language, Amharic); Phytolacca dodecandra] against aquatic macroinvertebrates Baetidae (Mayflies) and Hydropsychidae (Caddisflies), under laboratory conditions. In Ethiopia, toxic plant, berries of P...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Karunamoorthi K,Bishaw D,Mulat T

    更新日期：2008-11-01 00:00:00

  • LINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p.

    abstract：OBJECTIVE:Chordoma is a rare malignant tumor difficult to diagnose and treat. Long non-coding RNAs acting as novel biomarkers are frequently reported in numerous cancers. The purpose of this study was to investigate the role of long intergenic non-coding RNA 00662 (LINC00662) and its associated action mechanisms in cho...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_202002_20151

    authors： Wang CB,Wang Y,Wang JJ,Guo XL

    更新日期：2020-02-01 00:00:00

  • The efficacy of modified luteal phase support with intramuscular progesterone in IVF/ICSI cycles: a retrospective observational study.

    abstract：OBJECTIVE:The use of gonadotropin-releasing hormone agonist for ovulation triggering has become an intriguing topic in the last few years. As long as adequate luteal phase support is provided, it may be a valuable alternative to standard hCG triggering, associated with a significant reduction in OHSS incidence. Several...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Conforti A,Strina I,Mollo A,Amoroso R,Marrone V,Alviggi C,Marci R,de Placido G

    更新日期：2017-02-01 00:00:00

  • Role of TNF-alpha polymorphism in patients with nickel allergy: a marker of susceptibility to contact polysensitization.

    abstract：OBJECTIVE:Nickel allergy is the most frequent contact allergy in the industrialized country. In allergic contact dermatitis after the presentation of haptenated peptides by resident or newly recruited skin cells, activated CD8+ T cells release IFN-γ and TNF-α, these cytokines are potent activator of keratinocytes. The ...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Colagiovanni A,Di Renzo L,Sarlo F,Schiavino D,De Lorenzo A

    更新日期：2016-06-01 00:00:00

  • Effects of Vernonia cinerea less methanol extract on growth and morphogenesis of Candida albicans.

    abstract：BACKGROUND AND OBJECTIVES:Vernonia (V.) cinerea Less (Asteraceae) have many therapeutic uses in the practice of traditional medicine. The methanol extract of V cinerea, was screened for antiyeast activity against pathogenic yeast Candida albicans. MATERIALS AND METHODS:The antimicrobial activities were studied by usin...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Latha LY,Darah I,Jain K,Sasidharan S

    更新日期：2011-05-01 00:00:00

  • Downregulation of miR-145-5p correlates with poor prognosis in gastric cancer.

    abstract：OBJECTIVE:The aim of this study was to explore the clinical significance of miR-145-5p expression in gastric cancer (GC). PATIENTS AND METHODS:Expression of miR-145-5p was evaluated by qRT- PCR in tumor and normal gastric tissues in 145 GC patients. The correlation between the miR-145-5p expression and clinicopatholog...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：

    authors： Zhang Y,Wen X,Hu XL,Cheng LZ,Yu JY,Wei ZB

    更新日期：2016-07-01 00:00:00

  • Current views of common pediatric cancers - an update.

    abstract：:Advancements in pediatric cancers diagnostics clarity and treatments have greatly increased survival rates in the pediatric oncology population. Increased survival rates have turned new attention to studying psychosocial stressors and improvisation of the quality of life of the suffering cancer patients. The cancer tr...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章,评审

    doi：

    authors： An Q,Fan CH,Xu SM

    更新日期：2017-10-01 00:00:00

  • Resveratrol protects against oxidative damage of retinal pigment epithelium cells by modulating SOD/MDA activity and activating Bcl-2 expression.

    abstract：OBJECTIVE:Age-related macular degeneration (AMD) is mainly characterized by dysfunction of retinal pigment epithelium (RPE) cells. This study aimed to investigate the protective effects of resveratrol on oxidative damaged RPE cells. MATERIALS AND METHODS:Human D407 cells were divided into normal control (NC), H2O2 tre...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章

    doi：10.26355/eurrev_201901_16786

    authors： Yang Y,Wu ZZ,Cheng YL,Lin W,Qu C

    更新日期：2019-01-01 00:00:00

  • Long noncoding RNA ROR1-AS1 induces tumor metastasis and epithelial-mesenchymal transition by sponging miR-375 in nasopharyngeal carcinoma.

    abstract：OBJECTIVE:The vital role of long noncoding RNAs (lncRNAs) in tumor progression has been identified in numerous studies. Nasopharyngeal carcinoma (NPC) is one of the most ordinary malignant tumors. This study aims to explore the role of lncRNA ROR1-AS1 in the metastasis of NPC. PATIENTS AND METHODS:Real Time-quantitati...

    journal_title：European review for medical and pharmacological sciences

    pub_type： 杂志文章,收录出版

    doi：10.26355/eurrev_202001_19909

    authors： Hou J,Yan J,Ren XY,Zhu K,Du XY,Li JJ,Xu M

    更新日期：2020-01-01 00:00:00