HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications.

abstract：:A 67-year-old man, with multiple skin lesions that appeared over 2 years, had biopsies that disclosed granulomatous dermatitis with associated small yeasts. The urinary antigen test results were negative for Histoplasma infection; cultures from the biopsies did not grow any fungi or other potential pathogens. The ches...

journal_title：Archives of pathology & laboratory medicine

authors： Desai HB,Perkins PL,Procop GW

更新日期：2011-09-01 00:00:00

abstract：:Reported is an instance of bronchiolitis obliterans due to the accumulation of lipid-laden cells within bronchiolar walls and lumina. The bronchiolar lining had extensive squamous and goblet cell metaplasia with focal ulceration. Scattered foci of cholesterol pneumonia, composed of acicular crystals with an associated...

journal_title：Archives of pathology & laboratory medicine

authors： Heffelfinger SC,Weilbaecher DG,Lawrence EC,Johnson EH,Greenberg SD

更新日期：1988-06-01 00:00:00

abstract：:Two of three patients with erythropoietic protoporphyria showed pigment deposits with typical red porphyrin fluorescence on liver biopsy specimens. Birefringence of this pigment by polarized light is due to its crystalline nature, as demonstrated by electron microscopy. There was slight portal inflammation in these ca...

journal_title：Archives of pathology & laboratory medicine

authors： Bruguera M,Esquerda JE,Mascaró JM,Piñol J

更新日期：1976-11-01 00:00:00

abstract：:Examination of the bone marrow poses several unique challenges to the pathologist: it is a semisolid organ without helpful gross correlation, it exists in a dynamic state with the peripheral blood and other organs of the lymphohemopoietic system, and the diagnosis of diseases affecting bone marrow often depends heavil...

journal_title：Archives of pathology & laboratory medicine

authors： Hasserjian RP

更新日期：2008-04-01 00:00:00

abstract：:Rhabdoid tumor of the thyroid gland is a very rare neoplasm, characterized by significant metastatic potential. All of the 6 cases reported in the recent literature had poor outcomes. We report an additional case involving, to our knowledge, the oldest patient reported so far. A 67-year-old woman had a nodular goiter ...

journal_title：Archives of pathology & laboratory medicine

authors： Lai ML,Faa G,Serra S,Senes G,Daniele GM,Boi F,Mariotti S,Beauchemin M,Asa SL

更新日期：2005-03-01 00:00:00

abstract：:We report a case of primary Wilms' tumor of the endocervix in a 13-year-old girl. The tumor was polypoid, filled the vagina, and was attached to the endocervix by a stalk. Microscopic examination disclosed blastematous, epithelial, and stromal elements characteristic of Wilms' tumor. The patient's kidneys were normal ...

journal_title：Archives of pathology & laboratory medicine

authors： Bell DA,Shimm DS,Gang DL

更新日期：1985-04-01 00:00:00

abstract：:Three pseudosarcomatous lesions of the genitourinary tract are described. One that arose in the urinary bladder of a 59-year-old man was composed of atypical spindle cells admixed with inflammatory cells in an edematous stroma. The second lesion occurred in the stroma of a hyperplastic prostate gland of a 51-year-old ...

journal_title：Archives of pathology & laboratory medicine

authors： Young RH,Scully RE

更新日期：1987-04-01 00:00:00

abstract：:We studied 16 cases of bile duct adenomas, lesions that are distinct from Meyenburg complex. The former lesion is made up of small tubular structures with little or no lumen, is usually single and subcapsular, and is unrelated to cystic disease. It must be differentiated from early carcinoma. Of the six cases encounte...

journal_title：Archives of pathology & laboratory medicine

authors： Govindarajan S,Peters RL

更新日期：1984-11-01 00:00:00

abstract：:We report the case of a primary breast rhabdomyosarcoma in a 51-year-old white woman. The tumor occupied the upper outer quadrant of the right breast. There was no association with the underlying pectoral muscle, and the patient was free of any other benign or malignant neoplastic processes outside the breast. Microsc...

journal_title：Archives of pathology & laboratory medicine

authors： Kyriazis AP,Kyriazis AA

更新日期：1998-08-01 00:00:00

abstract：:Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females. Angiomyolipoma occurs most commonly in the kidneys. The liver represents the second most frequent site of involvement. Hepatic angiomyolipomas are composed of varying amounts of s...

journal_title：Archives of pathology & laboratory medicine

authors： Petrolla AA,Xin W

更新日期：2008-10-01 00:00:00

abstract：CONTEXT:Impairment of venous outflow manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. However, the finding of SDC is not specific for venous outflow impairment.Objectives.-To determine the specificity of SDC in liver biopsies for venous outflow impairment and to seek an explanation for SD...

journal_title：Archives of pathology & laboratory medicine

authors： Kakar S,Kamath PS,Burgart LJ

更新日期：2004-08-01 00:00:00

abstract：:We describe a case of granulomatous encephalitis caused by Bipolaris (Drechslera) hawaiiensis in an immunocompetent patient. An 18-year-old man with a seven-month history of seizures and right leg weakness was found by computed tomographic scan to have a left frontoparietal enhancing lesion. Biopsy of the lesion revea...

journal_title：Archives of pathology & laboratory medicine

authors： Morton SJ,Midthun K,Merz WG

更新日期：1986-12-01 00:00:00

abstract：:In 4% formaldehyde-fixed, paraffin-embedded tissues, PAS negativity for mycobacteria in the literature has been axiomatic. However, recent observations of disseminated human mycobacteriosis have shown that intracellular (phagocytosed) organisms stained strongly positive with the routine PAS technique. This staining wa...

journal_title：Archives of pathology & laboratory medicine

authors： Pappolla MA,Mehta VT

更新日期：1984-05-01 00:00:00

abstract：:Intravenously (IV) injected Evans blue dye consistently accumulates at particular areas in aortas of normal swine. Theses areas are also where IV injected tracer cholesterol accumulates. We studied the ultrastructural characteristics of blue vs nonblue areas in the abdominal aortas of both control and atherosclerotic ...

journal_title：Archives of pathology & laboratory medicine

authors： Imai H,Scott RF,Thomas WA

更新日期：1982-04-01 00:00:00

abstract：CONTEXT:Dysregulation of mediators of apoptosis is associated with carcinogenesis. For biliary duct cancers, p53 gene mutation is an important contributor to carcinogenesis. Mutations in the p53 gene affect transcription of the Fas gene, resulting in lack of Fas expression on cell membrane. It has been previously shown...

journal_title：Archives of pathology & laboratory medicine

authors： Jhala NC,Vickers SM,Argani P,McDonald JM

更新日期：2005-04-01 00:00:00

abstract：:Findings of a histochemical and ultrastructural study of the mucogenic cells of congenital adenomatoid malformation of lung indicate that these cells share features with goblet cells of bronchial or intestinal origin and do not indicate a similarity to normal gastric epithelium or glands, as has been previously sugges...

journal_title：Archives of pathology & laboratory medicine

authors： Daroca PJ Jr

更新日期：1979-05-01 00:00:00

abstract：:A premature infant had three pseudoaneurysms of the thoracic and abdominal aorta secondary to umbilical artery catheterization and sepsis. The infant had septicemia as the direct result of bacterial contamination of an umbilical artery catheter with Staphylococcus aureus. The thoracic pseudoaneurysm caused massive hem...

journal_title：Archives of pathology & laboratory medicine

authors： Rabin E,Vye MV,Farrell EE

更新日期：1986-05-01 00:00:00

abstract：CONTEXT:The inhibition of oncogenic kinase signaling is a successful strategy to treat both hematologic and solid malignancies. Patients with chronic myelogenous leukemia, lung adenocarcinoma, renal cell carcinoma, and gastrointestinal stromal tumors are experiencing tremendous clinical benefits from targeted therapies...

journal_title：Archives of pathology & laboratory medicine

authors： Marrari A,Wagner AJ,Hornick JL

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To describe the occurrence and significance of mucosal lymphangiectasia in gastric adenocarcinoma. DESIGN:One hundred consecutive gastrectomies for adenocarcinoma were reviewed, using 25 consecutive gastroscopically biopsied gastrectomy specimens with peptic ulcers as negative controls. SETTING:The specimen...

journal_title：Archives of pathology & laboratory medicine

authors： Mak KL,Hui PK,Chan WY,Leung KM

更新日期：1996-01-01 00:00:00

abstract：:Considering the variety of aberrant locations in which ectopic parathyroid adenomas may be found, these neoplasms can be difficult to identify and treat surgically. The results of radiographic and cytologic studies may lead to confusion of these neoplasms with lesions of thyroid origin. We present a case of an ectopic...

journal_title：Archives of pathology & laboratory medicine

authors： Pitsilos SA,Weber R,Baloch Z,LiVolsi VA

更新日期：2002-12-01 00:00:00

abstract：CONTEXT:In Thailand until 2005 there had been no external quality assessment scheme at the national level for blood coagulation tests. Only a few laboratories had an external quality assessment for these tests. In the year 2005, the Thailand National External Quality Assessment Scheme for Blood Coagulation was founded....

journal_title：Archives of pathology & laboratory medicine

authors： Tientadakul P,Opartkiattikul N,Wongtiraporn W

更新日期：2009-01-01 00:00:00

abstract：CONTEXT:-Small glandular proliferations of the breast encompass a variety of benign, atypical, and malignant lesions that show some overlapping morphologic features. Myoepithelial stains are frequently used in the workup of these lesions in order to rule out or establish a diagnosis of invasive carcinoma. Some benign l...

journal_title：Archives of pathology & laboratory medicine

authors： Ginter PS,Shin SJ,D'Alfonso TM

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:In the era of targeted cancer therapy, there is growing interest in developing novel therapeutic strategies against endometrial carcinoma, especially its most biologically aggressive variant, serous adenocarcinoma. Several publications have demonstrated that a significant proportion of uterine serous carcinomas...

journal_title：Archives of pathology & laboratory medicine

authors： Buza N,Roque DM,Santin AD

更新日期：2014-03-01 00:00:00

abstract：:To study the natural course of catheter-induced endocarditis secondarily infected with Staphylococcus epidermidis, 29 rabbits had catheters introduced surgically through the carotid artery to the aortic valve. Forty-eight hours later the catheters were removed from five rabbits. The rabbits were inoculated intravenous...

journal_title：Archives of pathology & laboratory medicine

authors： Shamsuddin D,Tuazon CU,Miller H,Shamsuddin AK,Friedman D

更新日期：1983-03-01 00:00:00

abstract：:Nephrogenic adenoma, also referred to as nephrogenic metaplasia, is an uncommon benign lesion of the urothelial tract, characterized by a circumscribed proliferation of tubules, cysts, and papillae lined by cells with low cuboidal to columnar epithelium. The diagnostic features that are useful in the recognition of th...

journal_title：Archives of pathology & laboratory medicine

authors： Kunju LP

更新日期：2010-10-01 00:00:00

abstract：:An unusual disorder of liver development, which is to our knowledge not described in the literature, was observed in a female infant who died, at the age of 25 weeks, of the sequelae of portal hypertension. At the time of autopsy, the enlarged liver revealed multiple small nodules histologically composed of trabecular...

journal_title：Archives of pathology & laboratory medicine

authors： Zimmermann A,Aebi-Ochsner C,Hess MW

更新日期：1982-05-01 00:00:00

abstract：:The salivary glands, despite their relatively simple morphology, give rise to more than 30 histologically distinct benign and malignant tumors. Salivary gland neoplasms comprise less than 2% of all tumors in humans and 3% of all head and neck tumors. They arise in the parotid gland in 80% of cases, and approximately 8...

journal_title：Archives of pathology & laboratory medicine

authors： Schneider M,Rizzardi C

更新日期：2008-02-01 00:00:00

abstract：CONTEXT.—:The separation of benign from malignant mesothelial proliferations is a difficult morphologic problem. Some mesotheliomas stain for programmed death ligand-1 (PD-L1). OBJECTIVE.—:To determine whether PD-L1 staining can separate mesotheliomas from reactive mesothelial proliferations (RMPs). DESIGN.—:We stain...

journal_title：Archives of pathology & laboratory medicine

authors： Derakhshan F,Ionescu D,Cheung S,Churg A

更新日期：2020-02-01 00:00:00

abstract：:Concerns regarding significant levels of inappropriate medical services--as high as 20% or more--continue to influence discussions regarding medical care quality, utilization, and costs. The basis of these concerns are findings from a series of studies of the appropriateness of use of several medical and surgical serv...

journal_title：Archives of pathology & laboratory medicine

authors： Kelly JT,Kellie SE

更新日期：1990-11-01 00:00:00

abstract：:Primary leiomyosarcoma of bone is extremely rare. A 60-year-old woman had a mass in the right femur that was studied immunohistochemically and by electron microscopy. Human smooth-muscle actomyosin was detected in tumor cells, but human skeletal-muscle myoglobin and lysozyme (muramidase) were not. Electron microscopy ...

journal_title：Archives of pathology & laboratory medicine

authors： Kawai T,Suzuki M,Mukai M,Hiroshima K,Shinmei M

更新日期：1983-08-01 00:00:00