当前位置： SCI文献检索 > SPINAL CORD期刊下所有文献 > Early versus late surgery for traumatic spinal cord injury: the results of a prospective Canadian cohort study.

Early versus late surgery for traumatic spinal cord injury: the results of a prospective Canadian cohort study.

Abstract：

STUDY DESIGN:A multicenter Canadian cohort study. OBJECTIVES:The objective of this study is to evaluate the impact of early versus late surgical decompression on motor neurological recovery after traumatic spinal cord injury (SCI). SETTING:Canadian acute care and SCI rehabilitation facilities. METHODS:A prospective cohort study of patients within the Ontario Spinal Cord Injury Registry program was performed. We considered SCI patients with an admission American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade of A through D, with magnetic resonance imaging-confirmed spinal cord compression. Grouped analysis was performed comparing the cohort of patients who received early surgery (<24 h after SCI) to those receiving delayed surgery (<24 h after SCI). The primary outcome was the change in ASIA motor score (AMS) occurring between hospital admission and rehabilitation discharge. RESULTS:A total of 35 (41.7%) patients underwent early surgery and 49 (58.3%) underwent late surgery. At admission, there was a greater proportion of patients within the early surgery group with more severe AIS grade A injuries. Of the 55 patients with neurological exam available at rehabilitation discharge, a greater proportion had at least a two-grade AIS improvement in the early-surgery group (P=0.01). The mean improvement in AMS at rehabilitation discharge was 20 points amongst early-surgery patients and 15 points amongst late-surgery patients (P=0.46). In the analysis investigating AMS improvement, adjusted for preoperative status and neurological level, there was a positive effect estimate for early surgical therapy that was statistically significant (P=0.01). CONCLUSION:The results here add weight to the growing body of literature, which supports the principle of early intervention in the setting of spinal trauma and SCI.

journal_name

Spinal Cord

journal_title

Spinal cord

authors

Wilson JR,Singh A,Craven C,Verrier MC,Drew B,Ahn H,Ford M,Fehlings MG

doi

10.1038/sc.2012.59

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

840-3

issue

11

eissn

1362-4393

issn

1476-5624

pii

sc201259

journal_volume

50

pub_type

杂志文章

相关文献

SPINAL CORD文献大全
  • The effect of long-term oral tadalafil treatment on corpus cavernosum function in an experimental spinal cord transection rat model.

    abstract：OBJECTIVES:The aim of this study was to investigate the pharmacological effects of long-term oral tadalafil treatment on the corpus cavernosum function in rats subjected to experimental spinal cord transection (SCT). METHODS:Thirty young adult, male Sprague–Dawley rats were randomly divided into five groups (n¼ 6, eac...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2013.61

    authors： Toksoz S,Erdem SR,Peskircioglu CL,Keskin U

    更新日期：2013-09-01 00:00:00

  • Efficacy and safety of phosphodieterase-5 inhibitors for treatment of erectile dysfunction secondary to spinal cord injury: a systemic review and meta-analysis.

    abstract：STUDY DESIGN:Systemic reviewObjective:We carried out a systematic review and meta-analysis to assess the efficacy and safety of phosphodieterase-5 (PDE5) inhibitors on erectile dysfunction (ED) secondary to spinal cord injury (SCI). METHODS:A literature review was performed to identify all published randomized, double...

    journal_title：Spinal cord

    pub_type： 杂志文章,meta分析,评审

    doi：10.1038/sc.2016.3

    authors： Jia DD,Shuang WB,Cheng T,Jia XM,Zhang M

    更新日期：2016-07-01 00:00:00

  • Factors associated with acute and chronic pain following traumatic spinal cord injuries.

    abstract：:Previous studies have estimated that between 25% and 45% of people with spinal cord injury report severe levels of chronic pain. Few studies have examined this longitudinally. This study examines the primary pain sites, intensity and variability of perceived pain in 76 patients, 6 weeks post injury and 45 patients fro...

    journal_title：Spinal cord

    pub_type： 临床试验,杂志文章

    doi：10.1038/sj.sc.3100569

    authors： Kennedy P,Frankel H,Gardner B,Nuseibeh I

    更新日期：1997-12-01 00:00:00

  • Feasibility of a novel diagnostic chart of intramedullary spinal cord tumors in magnetic resonance imaging.

    abstract：STUDY DESIGN:Retrospective chart review. OBJECTIVES:Each type of intramedullary spinal cord tumor (IMSCT) has specific anatomical and pathological features visible on magnetic resonance (MR) imaging. The purpose of this study was to investigate the accuracy of preoperative IMSCT diagnosis using our diagnostic chart of...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2014.127

    authors： Arima H,Hasegawa T,Togawa D,Yamato Y,Kobayashi S,Yasuda T,Matsuyama Y

    更新日期：2014-10-01 00:00:00

  • Tendon transfers in tetraplegic patients: the Cleveland experience.

    abstract：:The author has taken care of patients with spinal cord injury for over 30 years. A major part of these years was spent doing tendon transfers on the patients with tetraplegia. Thirteen were not better, but not worse out of the 285 patients who had an operation. All of the patients have had a period of rehabilitation, ...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3100475

    authors： Freehafer AA

    更新日期：1998-05-01 00:00:00

  • Suprascapular nerve entrapment in a patient with a spinal cord injury.

    abstract：STUDY DESIGN:Case report. OBJECTIVES:To describe a case of suprascapular nerve entrapment (SNE) in a patient with a spinal cord injury (SCI) as a cause of shoulder pain. SETTING:Physical Medicine and Rehabilitation Institute, Nancy, France. REPORT:Six months after the occurrence of acute paraplegia T9 ASIA, a 45-yea...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2010.89

    authors： Facione J,Beis JM,Kpadonou GT,Lagauche D,Touillet A,Braun M,Le Chapelain L,Paysant J

    更新日期：2011-06-01 00:00:00

  • Clinical associations with telomere length in chronic spinal cord injury.

    abstract：STUDY DESIGN:Cross-sectional study OBJECTIVES: To determine clinical factors associated with telomere length in persons with chronic spinal cord injury (SCI). SETTING:Veterans Affairs Medical Center, Boston, MA. METHODS:Two hundred seventy-eight participants with chronic SCI provided blood samples for measurement of ...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/s41393-019-0336-7

    authors： Monroe DM,Goldstein RL,Teylan MA,Hart JE,DeVivo I,Orr EH,Garshick E

    更新日期：2019-12-01 00:00:00

  • Use of a free jejunal graft for oesophageal reconstruction following perforation after cervical spine surgery: case report and review of the literature.

    abstract：STUDY DESIGN:: Single-subject (male, 16 years of age) case. OBJECTIVES:To demonstrate a suitable method for oesophageal repair after perforation as a complication of anterior spinal fusion in an individual with quadriplegia, and to review the literature on oesophageal perforation and repair. SETTING:University hospit...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3101439

    authors： Küntscher MV,Erdmann D,Boltze WH,Germann G

    更新日期：2003-10-01 00:00:00

  • The effect of tidal volumes on the time to wean persons with high tetraplegia from ventilators.

    abstract：STUDY DESIGN:Retrospective review of patient medical records comparing the outcomes of two groups of individuals with high-level (C3-4) tetraplegia- those with high-volume and those with low-volume mechanical ventilation. OBJECTIVES:To determine if higher volume mechanical ventilation contributes to faster weaning fro...

    journal_title：Spinal cord

    pub_type： 临床试验,杂志文章

    doi：10.1038/sj.sc.3100818

    authors： Peterson WP,Barbalata L,Brooks CA,Gerhart KA,Mellick DC,Whiteneck GG

    更新日期：1999-04-01 00:00:00

  • Vitamin D deficiency and insufficiency in Malaysian children with spina bifida.

    abstract：STUDY DESIGN:Cross-sectional study. OBJECTIVE:To determine the prevalence and potential risk factors of vitamin D deficiency and insufficiency among Malaysian children with spina bifida. SETTING:Four Malaysian tertiary hospitals. METHODS:Children with spina bifida were assessed for potential demographic, disease sev...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/s41393-020-0441-7

    authors： Fong CY,Ong FN,Ong LC,Khoo TB,Lee ML

    更新日期：2020-09-01 00:00:00

  • Patient experience survey in telemedicine for spinal cord injury patients.

    abstract：STUDY DESIGN:Patient feedback study. OBJECTIVES:To measure how patients value the telemedicine consultation service at the National Spinal Injuries Centre over a period of 8 months. SETTING:United Kingdom (south of England). METHODS:Telephone survey conducted by an external surveyor who does not work in the departme...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2014.247

    authors： Yuen J,Thiyagarajan CA,Belci M

    更新日期：2015-04-01 00:00:00

  • Tuberculosis of the spine (Pott's disease) presenting as 'compression fractures'.

    abstract：STUDY DESIGN:Case reports and survey of literature. OBJECTIVE:Case reports of two women with tuberculosis (TB) of the spine (Pott's disease) presenting with severe back pain and diagnosed as compression fracture are described. Physicians should include Pott's disease in the differential diagnosis when patients present...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3101365

    authors： Dass B,Puet TA,Watanakunakorn C

    更新日期：2002-11-01 00:00:00

  • Effect of detrusor botulinum toxin a injection on urothelial dysfunction in patients with chronic spinal cord injury: a clinical and immunohistochemistry study before and after treatment.

    abstract：OBJECTIVE:The objective of this study is to investigate the changes of urothelial junction proteins, apoptosis and suburothelial inflammation after detrusor injection of botulinum toxin A (BoNT-A) in patients with spinal cord injury (SCI) and neurogenic detrusor overactivity (NDO). METHODS:A total of 26 patients with ...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2015.241

    authors： Chen SF,Chang CH,Kuo HC

    更新日期：2016-10-01 00:00:00

  • Targeting inflammation to influence cognitive function following spinal cord injury: a randomized clinical trial.

    abstract：STUDY DESIGN:This study was a randomized, parallel-group, controlled clinical trial. OBJECTIVES:The purpose of this study was to examine the efficacy of targeting inflammation as a means of improving cognitive function in individuals with spinal cord injury. SETTING:Participants were recruited from the Niagara region...

    journal_title：Spinal cord

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/sc.2016.96

    authors： Allison DJ,Josse AR,Gabriel DA,Klentrou P,Ditor DS

    更新日期：2017-01-01 00:00:00

  • Use of pulsed irrigation evacuation in the management of the neuropathic bowel.

    abstract：:Management of the neuropathic bowel is one of the major issues in the treatment of patients with severe spinal cord injury (SCI). Pulsed irrigation evacuation (PIE) has been evaluated in several small studies for the clearing of fecal impactions in patients with a neuropathic bowel. We evaluated our experience with 39...

    journal_title：Spinal cord

    pub_type： 临床试验,杂志文章

    doi：10.1038/sj.sc.3100491

    authors： Puet TA,Jackson H,Amy S

    更新日期：1997-10-01 00:00:00

  • Vesicoureteral reflux in the early stage of spinal cord injury: a retrospective study.

    abstract：STUDY DESIGN:A retrospective study. OBJECTIVES:To investigate the risk factors of vesicoureteral reflux in the early stage of spinal cord injury. SETTING:Japan. METHODS:Urological evaluation, including cystography and urodynamic study was performed in patients in the early stage of spinal cord injury. The patients w...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3101091

    authors： Suzuki T,Ushiyama T

    更新日期：2001-01-01 00:00:00

  • Vestibular function after spinal cord injury: preliminary results.

    abstract：STUDY DESIGN:The excitability of the vestibular apparatus and pathways was studied in 10 patients with acute spinal cord injury (ASCI) and in 7 patients with chronic spinal cord injury (CHSCI). OBJECTIVES:Proprioceptive input that may be lost after spinal cord injury (SCI) is needed for integration with vestibular sig...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2008.163

    authors： Ribarić-Jankes K,Cobeljić R,Svetel M,Pesić B

    更新日期：2009-05-01 00:00:00

  • Sexual problems of women with spinal cord injury in Turkey.

    abstract：OBJECTIVES:Spinal cord injury (SCI) is a traumatic event that affects many facets of the injured people's lives. One aspect is sexual functioning. The purpose of this study is to identify the sexual problems of women with SCI and determine their level of knowledge about sexuality. METHODS:Twenty-six women with SCI for...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2013.161

    authors： Celik EC,Akman Y,Kose P,Arioglu P,Karatas M,Erhan B

    更新日期：2014-04-01 00:00:00

  • Descriptive study of earthquake-related spinal cord injury in Nepal.

    abstract：STUDY DESIGN:Descriptive study. OBJECTIVES:To describe the epidemiological features of spinal cord injury (SCI) following the 2015 earthquakes in Nepal. SETTING:Spinal Injury Rehabilitation Centre, Kavre, Nepal. METHODS:Data were collected from the medical records of all earthquake-related patients seen from 25 Apri...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2017.25

    authors： Groves CC,Poudel MK,Baniya M,Rana C,House DR

    更新日期：2017-07-01 00:00:00

  • Intramedullary thoracic tuberculoma.

    abstract：STUDY DESIGN:Case report. OBJECTIVE:To report a rare case of intramedullary thoracic tuberculoma. SETTING:China Rehabilitation Research Center, Beijing, China. CASE REPORT:A 42-year-old Chinese man presented with the complaints of weakness of the lower extremities and urinary retention. Neurological examinations con...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2009.58

    authors： Liu YD,Wang FY,Xu JM,Guan Y,Guan H

    更新日期：2010-01-01 00:00:00

  • Bacteriological investigation of infected pressure ulcers in spinal cord-injured patients and impact on antibiotic therapy.

    abstract：STUDY DESIGN:Retrospective. OBJECTIVES:To improve the use of bacteriological results for treating spinal cord-injured patients with infected pressure ulcers. SETTING:Microbiology and Orthopaedics Department, Ambroise Paré University Hospital, Boulogne-Billancourt, France. METHODS:Tissue specimens, sampled at the end...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3101568

    authors： Heym B,Rimareix F,Lortat-Jacob A,Nicolas-Chanoine MH

    更新日期：2004-04-01 00:00:00

  • Review of the efficacy and safety of transanal irrigation for neurogenic bowel dysfunction.

    abstract：STUDY DESIGN:Neurogenic bowel dysfunction (NBD) is a common occurrence after spinal cord injury (SCI) and in patients with spina bifida or multiple sclerosis. The impact of NBD on well-being is considerable, affecting both physical and psychological aspects of quality of life. Transanal irrigation (TAI) of the colon pr...

    journal_title：Spinal cord

    pub_type： 杂志文章,评审

    doi：10.1038/sc.2010.5

    authors： Emmanuel A

    更新日期：2010-09-01 00:00:00

  • Follow-up care for persons with spinal cord injury living in the community: a systematic review of interventions and their evaluation.

    abstract：STUDY DESIGN:Systematic review. OBJECTIVES:(1) To describe and compare follow-up care programmes, performed by rehabilitation centres, for persons with spinal cord injury (SCI) and (2) to describe the effects of these programmes regarding the occurrence of secondary impairments, well-being, the quality and costs of ca...

    journal_title：Spinal cord

    pub_type： 杂志文章,评审

    doi：10.1038/sj.sc.3101750

    authors： Bloemen-Vrencken JH,de Witte LP,Post MW

    更新日期：2005-08-01 00:00:00

  • Comparison of ambulatory versus video urodynamics in patients with spinal cord injury.

    abstract：OBJECTIVE:To compare the data obtained through video urodynamics (VUD) with those obtained through one voiding cycle ambulatory urodynamics monitoring (AUM) in patients with spinal cord injury (SCI). METHODS:A comparative study was conducted in 69 patients with SCI (mean age±s.d. 44±16.9 years), 51 men and 18 women, w...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sc.2014.9

    authors： Vírseda-Chamorro M,Salinas-Casado J,de la Marta-García M,Esteban-Fuertes M,Méndez S

    更新日期：2014-07-01 00:00:00

  • Expansive cervical laminoplasties--observations on comparative changes in spinous process lengths following longitudinal laminal divisions using autogenous bone or hydroxyapatite spacers.

    abstract：:Expansive laminoplasty is devised to preserve the posterior structures, including the original length of the spinous process which anchors the nucheal muscles, in order to prevent the postoperative development of instability and cervical kyphosis due to structural loss and poor tone of the nucheal muscles, which can r...

    journal_title：Spinal cord

    pub_type： 临床试验,杂志文章

    doi：10.1038/sc.1996.132

    authors： Hoshi K,Kurokawa T,Nakamura K,Hoshino Y,Saita K,Miyoshi K

    更新日期：1996-12-01 00:00:00

  • Is body-weight-supported treadmill training or robotic-assisted gait training superior to overground gait training and other forms of physiotherapy in people with spinal cord injury? A systematic review.

    abstract：STUDY DESIGN:Systematic review about randomised trials comparing different training strategies to improve gait in people with spinal cord injuries (SCI). OBJECTIVES:The aim of this systematic review was to compare the effectiveness of body-weight-supported treadmill training (BWSTT) and robotic-assisted gait training ...

    journal_title：Spinal cord

    pub_type： 杂志文章,评审

    doi：10.1038/sc.2017.31

    authors： Mehrholz J,Harvey LA,Thomas S,Elsner B

    更新日期：2017-08-01 00:00:00

  • Amenorrhoea in newly spinal cord injured women: an effect of hyperprolactinaemia?

    abstract：STUDY DESIGN:Prospective, single centre study. OBJECTIVES:Previous studies have suggested a relationship between stress reaction and elevated levels of prolactine. The aim of the present study was to investigate if there was a relationship between s-prolactine and menstrual cycle status following spinal cord injury (S...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3102095

    authors： Rutberg L,Fridén B,Karlsson AK

    更新日期：2008-03-01 00:00:00

  • Rehabilitation of spinal cord injury in the national rehabilitation center for the disabled of Japan: profile of a spinal service.

    abstract：:The National Rehabilitation Center for the Disabled (hereunder abbreviated NRC) in Japan was established in 1979. It consists of four divisions: the hospital, the rehabilitation training center, the research institute, and the information service section. The spinal unit has been functioning and cooperating corelative...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3100534

    authors： Suyama T,Nihei R,Kimura T,Yano H,Tobimatsu Y,Hatsuyama Y,Nakamura R,Mizukami M

    更新日期：1997-11-01 00:00:00

  • A systematic review of risk factors for the development and recurrence of pressure ulcers in people with spinal cord injuries.

    abstract：STUDY DESIGN:A systematic review was undertaken, based upon methods recommended for effectiveness questions but adapted to identify observational risk factor (RF) studies. OBJECTIVES:The literature identifies many RFs for pressure ulcer (PU) recurrence and development; however, RFs independently predictive of PU devel...

    journal_title：Spinal cord

    pub_type： 杂志文章,meta分析,评审

    doi：10.1038/sc.2013.29

    authors： Marin J,Nixon J,Gorecki C

    更新日期：2013-07-01 00:00:00

  • Utilization, access and satisfaction with primary care among people with spinal cord injuries: a comparison of three countries.

    abstract：STUDY DESIGN:Cross-sectional; survey. OBJECTIVES:To describe the utilization, accessibility and satisfaction of primary and preventive health-care services to individuals with long-term spinal cord injuries, and compare results among three countries: the United States, Canada and the United Kingdom. SETTING:The Canad...

    journal_title：Spinal cord

    pub_type： 杂志文章

    doi：10.1038/sj.sc.3101933

    authors： Donnelly C,McColl MA,Charlifue S,Glass C,O'Brien P,Savic G,Smith K

    更新日期：2007-01-01 00:00:00