Bacteriological investigation of infected pressure ulcers in spinal cord-injured patients and impact on antibiotic therapy.

Abstract:

STUDY DESIGN:Retrospective. OBJECTIVES:To improve the use of bacteriological results for treating spinal cord-injured patients with infected pressure ulcers. SETTING:Microbiology and Orthopaedics Department, Ambroise Paré University Hospital, Boulogne-Billancourt, France. METHODS:Tissue specimens, sampled at the end of the surgical intervention from unbridled and cleaned ulcers were analysed. Drainage liquids were cultured at day 1 (D1) and day 5 (D5) postsurgery. For part of the patients, a presurgery superficial sample was analysed and compared with the surgical and postsurgical samples. RESULTS:In all, 168 surgical samples from 101 patients, 183 D1 and 104 D5 wound drainage liquids were included in this study. Out of the 168 surgical samples 17 (10%) had a negative culture, whereas 151 (90%) had a positive culture. For drainage liquids, the culture was negative in 48% and 56% of the samples at D1 and D5, respectively. The most frequently isolated species were enterobacteria, followed by staphylococci and streptococci. CONCLUSION:Culturing deep tissue specimens sampled from the surgically cleaned and unbridled ulcers allows for the isolation of the bacterial species that are really involved in the ulcer infection. As the identification of these bacteria and their antibiotic susceptibility are available, when the culture results of the D1 postsurgical drainage liquid is also available, it is easier to choose targeted antibiotic treatment.

journal_name

Spinal Cord

journal_title

Spinal cord

authors

Heym B,Rimareix F,Lortat-Jacob A,Nicolas-Chanoine MH

doi

10.1038/sj.sc.3101568

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

230-4

issue

4

eissn

1362-4393

issn

1476-5624

pii

3101568

journal_volume

42

pub_type

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