Abstract:
:Despite the advent of effective antiretroviral therapy (ART), HIV-seropositive injection drug users (IDU) continue to suffer from elevated levels of morbidity and mortality. Evidence is needed to identify social- and structural-level barriers to effective ART. We investigated the impact of homelessness on plasma HIV RNA response among illicit drug users initiating ART in a setting with free and universal access to HIV care. We accessed data from a long-running prospective cohort of community-recruited IDU linked to comprehensive HIV clinical monitoring and ART dispensation records. Using Cox proportional hazards with recurrent events modeling, we estimated the independent effect of homelessness on time to plasma HIV viral load suppression. Between May 1996 and September 2009, 247 antiretroviral naïve individuals initiated ART and contributed 1755 person-years of follow-up. Among these individuals, the incidence density of plasma HIV RNA suppression less than 500 copies/mm(3) was 56.7 (95% confidence interval [CI]: 46.9-66.0) per 100 person-years. In unadjusted analyses, homelessness was strongly associated with lower rates suppression (hazard ratio = 0.56, 95% CI: 0.40-0.78, p = 0.001), however, after adjustment for adherence this association was no longer significant (adjusted hazard ratio = 0.79, 95% CI: 0.56-1.11, p = 0.177). Homelessness poses a significant structural barrier to effective HIV treatment. However, since this relationship appears to be mediated by lower levels of ART adherence, interventions to improve adherence among members of this vulnerable population are needed.
journal_name
AIDS Patient Care STDSjournal_title
AIDS patient care and STDsauthors
Milloy MJ,Kerr T,Bangsberg DR,Buxton J,Parashar S,Guillemi S,Montaner J,Wood Edoi
10.1089/apc.2011.0169subject
Has Abstractpub_date
2012-01-01 00:00:00pages
60-7issue
1eissn
1087-2914issn
1557-7449journal_volume
26pub_type
杂志文章abstract::The purpose of this study was to evaluate the relationship between the coping self-efficacy (CSE) scale and adherence to HIV medication in men and women enrolled in a large HIV treatment program in Kenya. Data were collected from a sample of 354 volunteers attending Nazareth Hospital's nine satellite clinics located i...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2011.0125
更新日期:2011-09-01 00:00:00
abstract::The purpose of this study was to examine the results of implementing a rapid counselor-based HIV testing program in community pharmacies. A prospective cross-sectional study was conducted on a convenience sample of clients at five community pharmacies in New York City (NYC). In 294 days of pharmacy testing, 2805 clien...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0076
更新日期:2013-08-01 00:00:00
abstract::Recommendations suggest that older children and adolescents perinatally infected with HIV (PHIV+) be informed of their HIV diagnosis; however, delayed disclosure is commonly reported. This study examined the prevalence and timing of HIV disclosure to PHIV+ adolescents and the associations between the timing of disclos...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2010.0161
更新日期:2011-04-01 00:00:00
abstract::Ten years after the Centers for Disease Control and Prevention recommended universal HIV screening, rates remain low. Internal medicine residents are the front-line medical providers for large groups of patients. We evaluated the knowledge of internal medicine residents about HIV testing guidelines and examined adhere...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2018.0035
更新日期:2018-05-01 00:00:00
abstract::Gastric syphilis in the setting of HIV is rare in the literature with only one other case reported. Herein, we present a case of a 40-year-old HIV-infected man with gastric syphilis. Evaluation revealed a rapid plasma reagin (RPR) of 1:2056, and cerebrospinal fluid with evidence of neurosyphilis. An esophagogastroduod...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/apc.2005.19.281
更新日期:2005-05-01 00:00:00
abstract::Growth failure is a common problem in HIV-infected children. The extent to which this growth failure could be reversed after the children receive antiretroviral therapy (ART) is not known. This study assessed the incidence of growth failure in HIV-infected Thai children, impact of ART on growth, and the predictors of ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2009.0093
更新日期:2009-12-01 00:00:00
abstract::Lack of access to health care is often blamed for poor health outcomes, but this effect is not supported by existing HIV/AIDS literature. The authors examined the association between access to care and survival time after progression to AIDS, using survival analysis methods. This study combined data from two CDC spons...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910252972276
更新日期:2002-05-01 00:00:00
abstract::Patient adherence (the degree to which patients follow their therapeutic regimen as prescribed within a set period of time) and persistence (the time to treatment discontinuation, with a permissible gap) with drug therapy are essential components of HIV/AIDS treatment. Select community pharmacies offer specialized ser...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,多中心研究
doi:10.1089/apc.2012.0189
更新日期:2012-09-01 00:00:00
abstract::The prevalence of smoking in HIV-infected subjects is high. As a smoking cessation aid, varenicline (Champix(®), Pfizer, Saint-Laurent, QC, Canada or Chantix(®), Pfizer, Mission, KS) has not been previously evaluated in HIV-infected smokers. In this multicenter pilot open label study, varenicline 1.0 mg was used twice...
journal_title:AIDS patient care and STDs
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1089/apc.2011.0199
更新日期:2012-01-01 00:00:00
abstract::The first generation of young people with perinatally acquired HIV is moving into adulthood, precipitating a transition from pediatric to adult care. As the first research appraisal of Australian clinician perspectives on this process, this article makes a unique contribution by examining the particular challenges ass...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0346
更新日期:2014-07-01 00:00:00
abstract::The increased longevity afforded by combination antiretroviral therapy in developed countries has led to an increased concern regarding senescence-related diseases in patients with human immunodeficiency virus (HIV) infection. Previous epidemiologic analyses have demonstrated an increased risk of chronic obstructive p...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0373
更新日期:2014-05-01 00:00:00
abstract::Autoimmune hepatitis (AIH) is a progressive, chronic hepatitis that has rarely been reported in HIV-infected individuals. Among patients who are candidates for hepatitis C virus (HCV) treatment, screening for AIH should be considered, because interferon has the potential to cause fulminant hepatic failure in the setti...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0149
更新日期:2009-06-01 00:00:00
abstract::The objective of this study was to describe the AIDS-defining conditions (ADC) and survival experience of pediatric AIDS cases (< 13 years age) reported in Puerto Rico. A descriptive analysis of the data gathered by the Puerto Rico AIDS Surveillance System was performed. Data for the 377 pediatric AIDS cases reported ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.1999.13.651
更新日期:1999-11-01 00:00:00
abstract::HIV stigma is rooted in culture and, therefore, it is essential to investigate it within the context of culture. The objective of this study was to examine the interrelationships among individualism-collectivism, HIV stigma, and social network support. A social network study was conducted among 118 people living with ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2014.0015
更新日期:2014-08-01 00:00:00
abstract::The purpose of this study was to describe what nurses know about HIV/AIDS in the First Affiliated Hospital of Jiamusi University, Heilongjiang Province, China. This was a descriptive, cross-sectional study. Only 7.9% of the nurse (n = 177) used condoms during their first experience of sexual intercourse. Eight-six per...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/1087291041518247
更新日期:2004-07-01 00:00:00
abstract::Guidelines for HIV primary care include visits every 3 months (up to 6 months in those with stable HIV). During pregnancy, women with HIV commonly attend once weekly to once monthly visits; however, after delivery, many are lost to follow-up. Our goal was to assess the frequency of loss to primary care follow-up postp...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0321
更新日期:2014-05-01 00:00:00
abstract::In HIV/AIDS, symptoms of depression or post-traumatic stress may interfere with important self-care behaviors such as the ability to adhere to one's medical treatment regimen. However, these problems may frequently go undetected in HIV care settings. The present study used brief self-report screening measures of depre...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1089/apc.2007.0069
更新日期:2008-04-01 00:00:00
abstract::Initial linkage to medical care is a critical step in the HIV care continuum leading to improved health outcomes, reduced morbidity and mortality, and decreased HIV transmission risk. We explored differences in perspectives on engagement in HIV care between people living with HIV who attended (Arrived) their initial m...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2018.0039
更新日期:2018-09-01 00:00:00
abstract::Mortality rates have decreased in medically compliant patients with HIV. More HIV-positive patients are requesting procedures that improve their quality of life. Reduction mammoplasty has been proven to predictably relieve back, neck, and shoulder pain related to macromastia. A case report is presented demonstrating a...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2005.19.353
更新日期:2005-06-01 00:00:00
abstract::The author presents the case history of the first patient with HIV-1 group O reported in the United States. The various human retroviruses and their clinical syndromes are described and the increasing diversity of HIV-1 strains and their spread are documented. The discovery of the divergent group O and its spread from...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/apc.1997.11.399
更新日期:1997-12-01 00:00:00
abstract::To determine the recent trends in AIDS-defining cancers in Western Europe, we analyzed the June 2002 European Non-Aggregate AIDS Data Set. We obtained the percentage of people with AIDS aged 15 years or older (n = 125,691; males, 99,560, females, 26,131) who had cancers as the initial AIDS-defining illness in 17 Europ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2004.18.501
更新日期:2004-09-01 00:00:00
abstract::Superior mesenteric artery (SMA) syndrome is a unique type of small bowel obstruction resulting from the compression of the duodenum by the SMA. This is a case of SMA syndrome in a cachectic 6-year-old boy with AIDS who presented after a 2.3-kg weight loss in the preceding month. Unfamiliarity with this condition coup...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729100318073
更新日期:2000-01-01 00:00:00
abstract::In 2010, New York (NY) passed new legislation mandating Emergency Departments (EDs) to offer HIV tests to patients 13-64 presenting for care. We evaluated the requirement's implementation and determined differences based on HIV prevalence or site-specific designated AIDS centers (DACs). We also evaluated policies for ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0124
更新日期:2014-02-01 00:00:00
abstract::To describe the epidemiology, outcomes, and risk factors of acute kidney injury (AKI) among human immunodeficiency virus (HIV)-infected patients admitted to the intensive care unit (ICU).We reviewed all the HIV-infected admissions to the ICU at Beijing Ditan hospital in the time span from June 2005 to May 2017 and col...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2018.0040
更新日期:2018-10-01 00:00:00
abstract::More than 30 million people are infected with HIV, and HIV remains the fifth leading cause of disability-adjusted life years worldwide. Antiretroviral therapy (ART) dramatically decreases mortality rate, but there are side effects, long-term toxicities, expenses, stigmas, and inconveniences associated with chronic tre...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2016.0226
更新日期:2016-12-01 00:00:00
abstract::Women at high-risk for HIV acquisition often face challenges that hinder their retention in HIV prevention trials. These same challenges may contribute to missed clinical care visits among HIV-infected women. This article, informed by the Gelberg-Andersen Behavioral Model for Vulnerable Populations, identifies factors...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0366
更新日期:2014-04-01 00:00:00
abstract::Studies on the use and outcome of highly active antiretroviral therapy (HAART) in HIV-infected Chinese have been scarce. We evaluated risk of progression to (1) nonaccidental death and (2) new AIDS-defining illness (ADI) or death in 223, 89.9% of 248 HIV-1-infected adult Chinese patients who were first initiated on HA...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.0037
更新日期:2007-02-01 00:00:00
abstract::There is a lack of updated estimates of HIV-2 infection in Italy. Moreover, lack of standardized HIV-2 viral load (VL) and drug resistance tests challenges clinical practice. Among 2941 HIV-positive patients followed in our center (Brescia, Northern Italy), 220 (7.5%) were African at the beginning of the study period....
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2007.0149
更新日期:2008-06-01 00:00:00
abstract::Among places where people living with HIV experience and anticipate HIV-related stigma, stigma in health care settings may be particularly harmful. Utilizing an exploratory sequential mixed methods approach, we conducted interviews (n = 76) and questionnaires (N = 460) with older adult women living with HIV enrolled i...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2018.0282
更新日期:2019-04-01 00:00:00
abstract::Although the primary mode of hepatitis C virus (HCV) transmission is exposure to blood products or injection drug use (IDU), studies have found varying independent risk factors for HCV infection among persons with no history of IDU or exposure to blood products. For HIV-infected women, sexual transmission may be anoth...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2009.0111
更新日期:2009-11-01 00:00:00