Bone screws have advantages in repair of experimental osteochondral fragments.

Abstract:

BACKGROUND:Cartilage defects are created on intraarticular osteochondral fragments at the entrance holes of fixation devices when these fragments are fixed to the original sites. Conventional fixation devices hinder repair of these defects and there is a latent risk of secondary osteoarthritis. We therefore developed a novel fixation device system consisting of bone screws made of cortical bone for osteochondral fragments to improve repair of these surface defects. QUESTIONS/PURPOSES:We asked whether bone screws had advantages over poly-L-lactic acid (PLLA) screws in terms of (1) gross assessment of the surface, (2) volume and histologic quality of the repair tissue, and (3) biomechanical assessment of the tissue stiffness. METHODS:We examined gross morphology, microCT, histology, and stiffness of the repaired tissue with PLLA (n = 32) and bone (n = 32) screws in a rabbit model of osteochondral fracture, compared with normal controls (n = 16). RESULTS:Gross morphology and histology revealed better quality with bone screws than with PLLA screws. Mean repaired volumes in microCT were 70.6% ± 14% with bone screws and 50.3% ± 15% with PLLA screws. Average stiffness values for PLLA screws, bone screws, and normal cartilage were 1.67 ± 0.54 N/mm, 2.63 ± 0.42 N/mm, and 3.15 ± 0.49 N/mm, respectively. CONCLUSIONS:Our results show better repaired tissue was observed for quality and quantity when chondral fractures were treated with bone screws than when treated with PLLA screws. CLINICAL RELEVANCE:Bone screws made of cortical bone may have applications in clinical situations for the fixation of intraarticular osteochondral fragments.

journal_name

Clin Orthop Relat Res

authors

Kono M,Mori R,Uchio Y

doi

10.1007/s11999-011-2175-5

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

2043-50

issue

7

eissn

0009-921X

issn

1528-1132

journal_volume

470

pub_type

杂志文章
  • The argument for the use of Metasul as an articulation surface in total hip replacement.

    abstract::Metasul metal-on-metal articulations have been used for 15 years in approximately 300,000 total hip replacements. We have used Metasul articulations in three clinical studies and have shown clinical success as measured by Harris hip scores and patient self-assessment; we also have had the usual mechanical complication...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000150343.66755.79

    authors: Dorr LD,Long WT,Sirianni L,Campana M,Wan Z

    更新日期:2004-12-01 00:00:00

  • Genetic association study of growth hormone receptor and idiopathic scoliosis.

    abstract::Although the etiology of scoliosis is multifactorial, genetic factors play an important role. Recent linkage studies on familial idiopathic scoliosis revealed multiple putative predisposition loci. A genetic association study is complementary to linkage studies in defining the genetic basis of complex traits of diseas...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/BLO.0b013e3180986dc2

    authors: Qiu XS,Tang NL,Yeung HY,Qiu Y,Cheng JC

    更新日期:2007-09-01 00:00:00

  • Controversies in the treatment of fingertip amputations. Conservative versus surgical reconstruction.

    abstract::Fingertip amputations are the most common type of amputation injury in the upper extremity. These injuries are either seen in the emergency room or in an office setting. These lesions are very frequent and require precise wound care for optimal results. The longer finger and the thumb, being the most distal and indepe...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-199808000-00008

    authors: Martin C,González del Pino J

    更新日期:1998-08-01 00:00:00

  • Three-dimensional shape of the dysplastic femur: implications for THR.

    abstract::This study evaluates the three-dimensional anatomy of the femur with congenital dysplasia of the hip (CDH) in comparison with healthy controls. Computed tomographic scans were obtained from 207 women (154 with dysplasia; 54 healthy controls) with an average age of 51.6 years (range, 18-82 years). Most of the dysplasti...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:30.3097/01.blo.0000096819.67494.32

    authors: Noble PC,Kamaric E,Sugano N,Matsubara M,Harada Y,Ohzono K,Paravic V

    更新日期:2003-12-01 00:00:00

  • Posttransplantation lymphoproliferative disorder in the knee.

    abstract::Lymphoproliferative disorders with primary presentation in a joint are extremely rare. Posttransplantation lymphoproliferative disorders are commonly extranodal at presentation but rarely involve joint structures. The authors describe a fatal case of posttransplantation lymphoproliferative disorder presenting in the k...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Pineda R,Wyard L,Tietjen R,Sieber S

    更新日期:1998-05-01 00:00:00

  • Abnormal skeletal growth in Kniest dysplasia caused by type II collagen mutations.

    abstract::Two unrelated patients with Kniest dysplasia had the same substitution of a CG dinucleotide in exon 12 of the COL2A1 gene that resulted in alternative splicing and interruption of the triple helix of a1(II) chains of Type II collagen. In early childhood, they shared the typical clinical and radiographic features of Kn...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Cole WG

    更新日期:1997-08-01 00:00:00

  • Septic arthritis in a Charcot joint.

    abstract::Two patients with Charcot joints developed septic arthritis. The infection in the first patient was treated successfully by repeated needle aspirations and parenteral oxacillin administration. In the second patient closed drainage and parenteral penicillin were not successful in eradicating the infection, and surgical...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Rubinow A,Spark EC,Canoso JJ

    更新日期:1980-03-01 00:00:00

  • Decreases in bone blood flow and bone material properties in aging Fischer-344 rats.

    abstract::The purpose of this study was to quantify precisely aging-induced changes in skeletal perfusion and bone mechanical properties in a small rodent model. Blood flow was measured in conscious juvenile (2 months old), adult (6 months old), and aged (24 months old) male Fischer-344 rats using radiolabeled microspheres. The...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200203000-00036

    authors: Bloomfield SA,Hogan HA,Delp MD

    更新日期:2002-03-01 00:00:00

  • Long term followup of thorough debridement and cancellous bone grafting of the femoral head for avascular necrosis.

    abstract::From 1977 to 1982, 13 patients were diagnosed with avascular necrosis of the femoral head. The diagnoses were made with a combination of clinical exams, radiographs, tomograms, and Tc99 bone scans. One hip was classified as Ficat Stage I, 9 as Stage II, and 5 as Stage III. There were 11 male and 2 female patients with...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Rosenwasser MP,Garino JP,Kiernan HA,Michelsen CB

    更新日期:1994-09-01 00:00:00

  • Factors affecting flexion after total knee arthroplasty.

    abstract:UNLABELLED:Results of total knee arthroplasty have demonstrated excellent pain relief and increased patient function, particularly in activities such as walking. This procedure has not always met the needs of certain ethnic and religious groups as well as younger patients who require greater magnitudes of knee flexion....

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/BLO.0b013e31812f785d

    authors: Dennis DA,Komistek RD,Scuderi GR,Zingde S

    更新日期:2007-11-01 00:00:00

  • Biomechanical analysis of foot function during gait and clinical applications.

    abstract::Temporal and distance gait factors, foot-switch contact patterns, ankle/subtalar joint motion, and center of foot pressure distribution have been used to evaluate normal and abnormal foot mechanics. A normal control group and selected patients with well defined pathologic conditions were studied to examine the effecti...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Katoh Y,Chao EY,Laughman RK,Schneider E,Morrey BF

    更新日期:1983-07-01 00:00:00

  • Role of fibrin sealants in surgical procedures on patients with hemostatic disorders.

    abstract::Fibrin sealants have until now been used to a very limited extent in patients with a bleeding diathesis. The authors have accumulated experience from 8 minor and 40 major surgical procedures, plus 10 circumcisions and 118 tooth extractions in 106 patients suffering from hemophilia A, B, or von Willebrand's disease. Mo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-199607000-00013

    authors: Martinowitz U,Schulman S,Horoszowski H,Heim M

    更新日期:1996-07-01 00:00:00

  • Critical roles of orthopaedic surgeon leadership in healthcare systems to improve orthopaedic surgical patient safety.

    abstract:BACKGROUND:The prevention of medical and surgical harm remains an important public health problem despite increased awareness and implementation of safety programs. Successful introduction and maintenance of surgical safety programs require both surgeon leadership and collaborative surgeon-hospital alignment. Documenta...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-012-2719-3

    authors: Kuo CC,Robb WJ 3rd

    更新日期:2013-06-01 00:00:00

  • Experimental instability of the ankle. A radiographic investigation.

    abstract::For determination of the optimal position in examining the ankle joint for anterior drawer sign and talar tilting, 12 legs freshly amputated above the knee were radiographically examined after successive transection of the lateral ankle ligaments in three different sequences. Apparatuses secured the position of the an...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Larsen E

    更新日期:1986-03-01 00:00:00

  • The influence of anesthesia and pain management on cognitive dysfunction after joint arthroplasty: a systematic review.

    abstract:BACKGROUND:Despite the overall success of total joint arthroplasty, patients undergoing this procedure remain susceptible to cognitive decline and/or delirium, collectively termed postoperative cognitive dysfunction. However, no consensus exists as to whether general or regional anesthesia results in a lower likelihood...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1007/s11999-013-3363-2

    authors: Zywiel MG,Prabhu A,Perruccio AV,Gandhi R

    更新日期:2014-05-01 00:00:00

  • Total knee arthroplasty using cruciate-retaining kinematic condylar prosthesis.

    abstract::The purpose of the current study was to evaluate the long-term results of the Kinematic I condylar prosthesis with retention of the posterior cruciate ligament. One hundred sixty-eight total knee arthroplasties in 118 patients (mean age, 65.2 years; range, 21-88 years) were inserted with cement, an all-polyethylene pa...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200107000-00007

    authors: Sextro GS,Berry DJ,Rand JA

    更新日期:2001-07-01 00:00:00

  • What General and Pain-associated Psychological Distress Phenotypes Exist Among Patients with Hip and Knee Osteoarthritis?

    abstract:BACKGROUND:Psychological distress can negatively influence disability, quality of life, and treatment outcomes for individuals with hip and knee osteoarthritis (OA). Clinical practice guidelines recommend a comprehensive disease management approach to OA that includes the identification, evaluation, and management of p...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/CORR.0000000000001520

    authors: Lentz TA,George SZ,Manickas-Hill O,Malay MR,O'Donnell J,Jayakumar P,Jiranek W,Mather RC 3rd

    更新日期:2020-12-01 00:00:00

  • Varus and valgus flexion laxity of total knee alignment methods in loaded cadaveric knees.

    abstract::Both total knee alignment methods, the anatomic and classic, seek to achieve stability in flexion and extension. However, posterior femoral condyle referencing (anatomic alignment) combined with perpendicular tibial resection (classic alignment) results in a 3 degree relative internal rotation of the femoral component...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200201000-00029

    authors: Romero J,Duronio JF,Sohrabi A,Alexander N,MacWilliams BA,Jones LC,Hungerford DS

    更新日期:2002-01-01 00:00:00

  • Vaccine-associated sarcomas in cats: a unique cancer model.

    abstract::Epidemiologic evidence supports a relationship between vaccination of cats for rabies and feline leukemia virus with the development of soft tissue sarcomas at the site of administration. These tumors are locally invasive and histologically aggressive. As with high-grade soft tissue sarcoma in humans, combination trea...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-200101000-00005

    authors: McNiel EA

    更新日期:2001-01-01 00:00:00

  • Bernese periacetabular osteotomy.

    abstract::Seventy-five symptomatic dysplastic hip joints (63 patients) were treated with the Bernese periacetabular osteotomy during a period of 44 months. The mean patients' age was 29 years (range, 13-56 years) and the female:male ratio was 3.4:1. Group III dysplasia according to Severin was seen in 50% and Group IV dysplasia...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Siebenrock KA,Schöll E,Lottenbach M,Ganz R

    更新日期:1999-06-01 00:00:00

  • Osteoid osteoma under the age of five years. The difficulty of diagnosis.

    abstract::Ninety-one cases of histologically confirmed osteoid osteoma were collected during an 11-year period; of them, seven (7.6%) had onset of symptoms while younger than five years of age. Special diagnostic difficulties were found in this specific age group: most cases were misdiagnosed or diagnosed incorrectly. The time ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Kaweblum M,Lehman WB,Bash J,Strongwater A,Grant AD

    更新日期:1993-11-01 00:00:00

  • Reliability of closed double helix electrode for functional electrical stimulation.

    abstract::The reliability of a closed double helix electrode in the lower limbs was studied. This electrode is an implanted intramuscular electrode and is used for a totally implantable functional electrical stimulation system. Eighty electrodes were evaluated retrospectively with a mean period of 15 months. The total implant t...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Kagaya H,Sharma M,Polando G,Marsolais EB

    更新日期:1998-01-01 00:00:00

  • Reliability of shoulder abduction strength measure for the Constant-Murley score.

    abstract::Reports using the Constant-Murley score often lack details regarding how strength measurement was performed, which may have an important impact on the results obtained. A description of the measurement is especially important when patients are unable to adopt the prescribed position of 90 degrees shoulder abduction, l...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-009-1007-3

    authors: Hirschmann MT,Wind B,Amsler F,Gross T

    更新日期:2010-06-01 00:00:00

  • Patellar tumors.

    abstract::Pain in the anterior knee has become synonymous with patella chondromalacia. However, pain also is the first sign of a tumor of the patella. Tumors of the patella are rare, but they often are mistaken for other benign lesions. Benign tumors of the patella are more frequent than malignant tumors (73% versus 27%). The m...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200108000-00007

    authors: Mercuri M,Casadei R

    更新日期:2001-08-01 00:00:00

  • Resection of the forefoot in rheumatoid arthritis.

    abstract::A long-term review of 272 resections of the metatarsal heads and bases of the phalanges in 128 patients with severe rheumatoid feet is presented. The longest follow-up is 11 years and the average follow-up was 4.7 years. Recurrent deformity and callus formation was usually due to a long metatarsal shaft. The operation...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-197505000-00036

    authors: Marmor L

    更新日期:1975-05-01 00:00:00

  • Nonspecific lower-back pain: surgical versus nonsurgical treatment.

    abstract:UNLABELLED:We review evidence-based treatments for patients seeking care for lower-back pain and patients who have been diagnosed with nonspecific lower-back pain. The review is based on selected systematic reviews and national and international guidelines for the treatment of lower-back pain. Additional randomized con...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000198721.75976.d9

    authors: Nordin M,Balagué F,Cedraschi C

    更新日期:2006-02-01 00:00:00

  • Epiphyseometaphyseal cupping of the distal femoral epiphysis following scurvy in infancy.

    abstract::Bilateral epiphyseometaphyseal cupping of the distal femoral epiphysis occurred in a 9-year-old girl with a history of infantile scurvy. This rare condition is characterized by a cup-shaped depression of the metaphyseal end, growth disturbance at the distal femoral epiphysis and knee flexion contracture which develops...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Hallel T,Malkin C,Garti R

    更新日期:1980-11-01 00:00:00

  • The immune response to implant materials in humans.

    abstract::The etiology of aseptic loosening of prosthetic joint replacement components is unclear. Implant materials have been considered biologically inert, but recently studies indicate that inflammatory reactions directed against the implanted materials may contribute to aseptic loosening. Data suggesting a progression from ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-199605000-00008

    authors: Wooley PH,Nasser S,Fitzgerald RH Jr

    更新日期:1996-05-01 00:00:00

  • Medical malpractice reform: the role of alternative dispute resolution.

    abstract:BACKGROUND:Alternative dispute resolution (ADR) refers to techniques used to resolve conflicts without going to the courtroom. As healthcare and malpractice costs continue to rise, there is growing interest in tactics such as early apology, mediation, and arbitration in the medical arena. QUESTIONS/PURPOSES:(1) Why is...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-011-2206-2

    authors: Sohn DH,Bal BS

    更新日期:2012-05-01 00:00:00

  • Spontaneous necrosis in osteosarcoma.

    abstract::The percentage of necrosis in a primary osteosarcoma after the patient has received preoperative chemotherapy is prognostic and is usually used to select subsequent chemotherapy. However, the percentage of necrosis that occurs spontaneously, without preoperative chemotherapy, has not been adequately studied. The exami...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Springfield DS,Schakel ME Jr,Spanier SS

    更新日期:1991-02-01 00:00:00