Vaccine-associated sarcomas in cats: a unique cancer model.

Abstract:

:Epidemiologic evidence supports a relationship between vaccination of cats for rabies and feline leukemia virus with the development of soft tissue sarcomas at the site of administration. These tumors are locally invasive and histologically aggressive. As with high-grade soft tissue sarcoma in humans, combination treatment with radiation therapy and surgery provides for optimum tumor control. Feline vaccine-associated sarcoma has become a difficult issue for the veterinary profession for legal, ethical, and clinical reasons. Although most research efforts have focused on therapeutic intervention, this tumor has great potential to provide an informative model for carcinogenesis and genetic susceptibility applicable to cancer in all species, including humans.

journal_name

Clin Orthop Relat Res

authors

McNiel EA

doi

10.1097/00003086-200101000-00005

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

21-7

issue

382

eissn

0009-921X

issn

1528-1132

pub_type

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